therapeutics News and Research

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Novel therapeutics targeting primary cilia may reverse neurodevelopmental disorders

Primary cilia are structures that act like antennas for cells to identify signals and occur less in mice affected by Fragile X syndrome since birth.

31 Jul 2020

Experimental mRNA-based vaccine protects animals against SARS-CoV-2

An experimental messenger RNA (mRNA)-based vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) elicits protective immune responses in mice and non-human primates, researchers report on July 23rd in the journal Cell.

27 Jul 2020

New approach is more effective in treating certain blood cancers

Some of the most promising advances in cancer treatment have centered on immunotherapies that rev up a patient's immune system to attack cancer.

24 Jul 2020

Study shows efficacy of L-Grb2 in preclinical models of ovarian and uterine cancer

The cover for issue 29 of Oncotarget features Figure 5, "In vivo effects of treatment with L-Grb2 in combination with anti-angiogenic therapy in an ovarian tumor model," by Lara, et al. which reported that adaptor proteins such as growth factor receptor-bound protein-2 play important roles in cancer cell signaling.

23 Jul 2020

New startup launched to overcome the challenge of delivering next-generation therapeutics

Harvard University's Office of Technology Development (OTD) and the Harvard T.H. Chan School of Public Health today announced the launch of Vesigen Therapeutics, a startup company that aims to overcome the challenge of delivering next-generation therapeutics, such as gene-editing complexes, RNA molecules, and other large proteins, to intracellular targets in specific tissues of interest.

23 Jul 2020

Simple DNA repeats can be the basis for genetic computers

Dr. Herbert asks what if our genome was far smarter than everyone previously believed? What if in the many DNA repeat elements lay the foundation for building a novel type of biocomputer?

22 Jul 2020

Scientist receives DoD grant to develop freeze-dried synthetic platelets

A Case Western Reserve University scientist, who has for more than a decade pioneered research into synthetic platelet substitutes, has been awarded a $3.8 million grant by the U.S. Department of Defense (DOD) to develop freeze-dried artificial platelets that can treat bleeding in wounded soldiers in the battlefield before they can be taken to a hospital.

22 Jul 2020

Gene biomarker can distinguish between atopic dermatitis and psoriasis with 100% accuracy

Mount Sinai researchers have pinpointed a single gene biomarker, nitride oxide synthase 2 (NOS2) that can distinguish atopic dermatitis (AD) and psoriasis with 100 percent accuracy using adhesive tape strips, a non-invasive alternative to skin biopsy.

22 Jul 2020

Novel nano drug candidate kills triple negative breast cancer cells

Researchers at the University of Arkansas have developed a new nano drug candidate that kills triple negative breast cancer cells.

21 Jul 2020

Study sheds light on protein involved in Huntington’s disease

Researchers have performed a new study that exposes complex details regarding the biology of the huntingtin protein (HTT), which causes Huntington’s disease.

20 Jul 2020

Researchers find a way to prevent SARS-CoV-2 virus from binding to cells

On July 1, the Texas A&M Engineering Experiment Station's (TEES) National Center for Therapeutics Manufacturing (NCTM) received funding from the National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL) to help find a way to prevent the SARS-CoV-2 virus from binding to cells, protecting people from future infections.

20 Jul 2020

Modified mRNAs improve efficiency of protein synthesis

Since mRNAs play a key role in protein synthesis in vivo, the use of mRNAs as medicines and for in vitro protein synthesis has been desired.

17 Jul 2020

Substances that target oxytocin receptors can help treat various diseases

Oxytocin is the so-called “cuddle hormone” or “love hormone” that plays a role in strengthening the relationship between the mother and child and controlling social bonding.

17 Jul 2020

Credit-card sized tool provides better understanding on breast cancer metastasis

A group of researchers from the University of Toronto have developed a credit-card sized tool for growing cancer cells outside the human body, which they believe will enhance their understanding of breast cancer metastasis.

From University of Toronto 16 Jul 2020

Researchers develop novel and promising approach for treatment of lung cancer

A new and promising approach for treatment of lung cancer has been developed by researchers at Lund University. The treatment combines a novel surgical approach with smart nanoparticles to specifically target lung tumors. The new study has been published in the July issue of Advanced Therapeutics.

16 Jul 2020

Dual inhibitor therapy may be safer for patients with chronic lymphocytic leukemia

Chronic lymphocytic leukemia (CLL) is the most common leukemia in adults. One in four new leukemia cases are CLL.

15 Jul 2020

UTMB researchers uncover new mechanism for designing dengue therapeutics

A multidisciplinary team from The University of Texas Medical Branch at Galveston has uncovered a new mechanism for designing antiviral drugs for dengue virus. The study is currently available in Proceedings of the National Academy of Sciences.

14 Jul 2020

New radiotracer provides a quantitative measure of disease progression after stroke

A new radiotracer, 18F-SynVesT-2, can directly assess synaptic density changes in the brain, providing an objective and quantitative measure of disease progression after stroke.

14 Jul 2020

NIH establishes clinical trial network to test vaccines and monoclonal antibodies for COVID-19

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), has established a new clinical trial network that aims to enroll thousands of volunteers in large-scale clinical trials testing a variety of investigational vaccines and monoclonal antibodies intended to protect people from COVID-19.

14 Jul 2020

Researchers develop new immunotherapy that prevents reoccurrence of breast cancer

New immunotherapy developed by researchers at Northwestern University dramatically extends the survival time of mice with triple-negative breast cancer, one of the most aggressive and difficult-to-treat forms of breast cancer.

14 Jul 2020

therapeutics News and Research

Novel therapeutics targeting primary cilia may reverse neurodevelopmental disorders

Experimental mRNA-based vaccine protects animals against SARS-CoV-2

New approach is more effective in treating certain blood cancers

Study shows efficacy of L-Grb2 in preclinical models of ovarian and uterine cancer

New startup launched to overcome the challenge of delivering next-generation therapeutics

Simple DNA repeats can be the basis for genetic computers

Scientist receives DoD grant to develop freeze-dried synthetic platelets

Gene biomarker can distinguish between atopic dermatitis and psoriasis with 100% accuracy

Novel nano drug candidate kills triple negative breast cancer cells

Study sheds light on protein involved in Huntington’s disease

Researchers find a way to prevent SARS-CoV-2 virus from binding to cells

Modified mRNAs improve efficiency of protein synthesis

Substances that target oxytocin receptors can help treat various diseases

Credit-card sized tool provides better understanding on breast cancer metastasis

Researchers develop novel and promising approach for treatment of lung cancer

Dual inhibitor therapy may be safer for patients with chronic lymphocytic leukemia

UTMB researchers uncover new mechanism for designing dengue therapeutics

New radiotracer provides a quantitative measure of disease progression after stroke

NIH establishes clinical trial network to test vaccines and monoclonal antibodies for COVID-19

Researchers develop new immunotherapy that prevents reoccurrence of breast cancer

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