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AI Uncovers Rare Mutations with Major Impact on Heart Health

Researchers at the Icahn School of Medicine at Mount Sinai have discovered unusual coding variants in 17 genes that provide insight into the molecular causes of coronary artery disease (CAD), the world's leading cause of morbidity and mortality.

12 Jun 2024

Shaping the Brain: Experience-Dependent Plasticity in Development, Learning and Memory

Explore the groundbreaking work of Mark Bear, a leading figure in neuroscience, as he shares insights on synaptic plasticity, learning, and the future of neurological research.

12 Jun 2024

SPT Labtech Brings the Power of Miniaturization to More Genomics Researchers with mosquito® Gen3

SPT Labtech, a global leader in the design, development and manufacture of automated instrumentation and consumables for life science applications, has expanded its nanoliter liquid handling portfolio with the launch of mosquito Gen3.

From SPT Labtech 12 Jun 2024

Super-Cooled Brain Cell Molecules Shed Light on Epilepsy Drug Action

By super cooling a molecule on the surface of brain cells down to about minus 180 degrees Celsius -; nearly twice as cold as the coldest places in Antarctica -; scientists at Johns Hopkins Medicine say they have determined how a widely-used epilepsy drug works to dampen the excitability of brain cells and help to control, although not cure, seizures.

11 Jun 2024

Whole Genome Sequencing Provides Answers Where Exome Sequencing Falls Short

Genetic mutations in human DNA can prevent proteins that perform important functions in the body from being formed correctly.

11 Jun 2024

Discovery Speeds Up Cyclic Peptide Production for Antibiotic Development

A discovery made by scientists at King's College London could speed up efforts to produce new antibiotics in the fight against antimicrobial resistance.

11 Jun 2024

Water-Soluble Bacterial Enzyme Could Enable Rapid Screening of Potential Antibiotics

A bacterial enzyme called histidine kinase is a promising target for new classes of antibiotics. However, it has been difficult to develop drugs that target this enzyme, because it is a "hydrophobic" protein that loses its structure once removed from its normal location in the cell membrane.

11 Jun 2024

Lung Organoids Shed Light on Pseudomonas aeruginosa's Invasive Tactics

How do pathogens invade the lungs? Using human lung microtissues, a team at the Biozentrum of the University of Basel has uncovered the strategy used by a dangerous pathogen.

11 Jun 2024

CSHL Researchers Reveal New Protein Networks in RNA Splicing Regulation

Bodybuilders and cellular mechanisms agree generating protein is a heavy lift. To complete the task, cells rely on complexes called spliceosomes.

11 Jun 2024

Epitope Binning-Seq: Revolutionizing Antibody Drug Discovery

Monoclonal antibodies are powerful tools in medicine due to their remarkable ability to target specific sites on antigens (foreign invaders) called epitopes.

11 Jun 2024

Engineered Enzyme Boosts Gene Editing Efficiency for Potential Cystic Fibrosis Treatment

Researchers at the Broad Institute of MIT and Harvard have enhanced a gene-editing technology, enabling it to efficiently insert or substitute entire genes in the genome of human cells.

11 Jun 2024

Innovative Gene Editing Elevates Photosynthetic Efficiency in Food Crops

A team from the Innovative Genomics Institute at the University of California, Berkeley (UCB) has produced an increase in gene expression in a food crop by changing its upstream regulatory DNA.

10 Jun 2024

Study Highlights Key Protein-Lipid Interactions in Mitochondrial Energy Production

By studying mutations in yeast and human cells, Johns Hopkins Medicine scientists say they have found that biochemical bonds between fats and proteins in the mitochondrion, the cell's powerhouse, play a crucial role in how our cells produce energy.

10 Jun 2024

Dundee Scientists Reveal Inner Workings of PINK1 Molecular Switch in Parkinson's Disease

Scientists at the University of Dundee have uncovered the inner relay of a molecular switch that protects the brain against the development of Parkinson's disease.

10 Jun 2024

Study Finds Essential Role of Orco Protein in Ant Olfactory Neuron Survival and Social Interaction

While smell plays a considerable role in the social interactions of humans-;for instance, signaling fear or generating closeness-;for ants, it is vitally important.

10 Jun 2024

Study Unveils Broader Immune Response in EBV-MS Connection

Epstein-Barr virus (EBV) may have a greater effect on the development of multiple sclerosis (MS) than previously believed due to a higher level of cross-reactivity, which occurs when the immune system binds to the incorrect target.

10 Jun 2024

New research identifies and mitigates bias in CRISPR-Cas9 gene editing

A phenomics approach to study proximity bias and the unrelated chromosomal truncations.

10 Jun 2024

Unveiling the Chemical Secrets of Coral Reefs and Insights into Marine Health

What species exist on this coral reef, and how healthy are they?

7 Jun 2024

Unraveling the Mysteries of Killifish Embryonic Development

The annual killifish lives in regions with extreme drought. A research group at the University of Basel now reports in "Science" that the early embryogenesis of killifish diverges from that of other species.

7 Jun 2024

Study Reveals Diversity of DNA Transposons and Expands Genome Engineering Toolbox

In a study published in Cell, a research team led by Zhang Yong'e and WANG Haoyi from the Institute of Zoology of the Chinese Academy of Sciences has characterized the diversity of DNA transposons and expanded the genome engineering toolbox.

7 Jun 2024

Research News and Research

AI Uncovers Rare Mutations with Major Impact on Heart Health

Shaping the Brain: Experience-Dependent Plasticity in Development, Learning and Memory

SPT Labtech Brings the Power of Miniaturization to More Genomics Researchers with mosquito® Gen3

Super-Cooled Brain Cell Molecules Shed Light on Epilepsy Drug Action

Whole Genome Sequencing Provides Answers Where Exome Sequencing Falls Short

Discovery Speeds Up Cyclic Peptide Production for Antibiotic Development

Water-Soluble Bacterial Enzyme Could Enable Rapid Screening of Potential Antibiotics

Lung Organoids Shed Light on Pseudomonas aeruginosa's Invasive Tactics

CSHL Researchers Reveal New Protein Networks in RNA Splicing Regulation

Epitope Binning-Seq: Revolutionizing Antibody Drug Discovery

Engineered Enzyme Boosts Gene Editing Efficiency for Potential Cystic Fibrosis Treatment

Innovative Gene Editing Elevates Photosynthetic Efficiency in Food Crops

Study Highlights Key Protein-Lipid Interactions in Mitochondrial Energy Production

Dundee Scientists Reveal Inner Workings of PINK1 Molecular Switch in Parkinson's Disease

Study Finds Essential Role of Orco Protein in Ant Olfactory Neuron Survival and Social Interaction

Study Unveils Broader Immune Response in EBV-MS Connection

New research identifies and mitigates bias in CRISPR-Cas9 gene editing

Unveiling the Chemical Secrets of Coral Reefs and Insights into Marine Health

Unraveling the Mysteries of Killifish Embryonic Development

Study Reveals Diversity of DNA Transposons and Expands Genome Engineering Toolbox

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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