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Single-nucleus RNA sequencing helps compare transcriptional responses to acute cocaine

The lab of Jeremy Day, Ph.D., at the University of Alabama at Birmingham, has used single-nucleus RNA sequencing approaches to compare transcriptional responses to acute cocaine in 16 unique cell populations from a portion of the brain called the nucleus accumbens, or NAc.

From University of Alabama 10 Jul 2020

Metabolomics can help understand the impact of calorie-restricted diets on aging

Changes in a few small molecules involved in a cell's metabolism seem to indicate whether a restricted "life extension" diet will actually extend, shorten, or have no effect on lifespan, a study of fruit flies has found.

10 Jul 2020

Structural analysis of SARS-CoV-2 spike protein offers clues about the virus' evolution

Researchers at the Francis Crick Institute have characterized the structure of the SARS-CoV-2 spike protein as well as its most similar relative in a bat coronavirus. The structures provide clues about how the spike evolved and could help inform vaccine design.

10 Jul 2020

Study shows engineered natural killer immune cells can directly kill tumor cells

According to a study, researchers have successfully designed natural killer immune cells that destroy head and neck tumor cells in mice.

8 Jul 2020

BU researchers develop new way to better understand human cell communication

Researchers from Boston University School of Medicine have developed and implemented a new way to better understand how human cells communicate with each other, how this communication is disrupted in human diseases and how this can be corrected pharmacologically.

7 Jul 2020

Organoids reveal inflammatory processes that play a role in infectious diseases

Research is employing mini-organs to model the digestive tract in the laboratory setting. These supposed organoids shed light on the inflammatory processes.

6 Jul 2020

Researchers track how key brain receptor works

For the first time, researchers in the lab of CSHL Professor Hiro Furukawa have been able to track each atom in the NMDA receptor, an important brain protein, as it transmits or inhibits neural signals.

1 Jul 2020

Engineered T-cells attack solid-tumor cancer cells from humans and mice

A method known as CAR-T therapy has been used successfully in patients with blood cancers such as lymphoma and leukemia.

1 Jul 2020

Lab-grown 'mini-brains' can be infected by SARS-CoV-2 virus

A multidisciplinary team from two Johns Hopkins University institutions, including neurotoxicologists and virologists from the Bloomberg School of Public Health and infectious disease specialists from the school of medicine, has found that organoids (tiny tissue cultures made from human cells that simulate whole organs) known as "mini-brains" can be infected by the SARS-CoV-2 virus that causes COVID-19.

1 Jul 2020

COVID-19 virus can infect heart cells in a lab dish, study shows

A new study shows that SARS-CoV-2, the virus that causes COVID-19 (coronavirus), can infect heart cells in a lab dish, indicating it may be possible for heart cells in COVID-19 patients to be directly infected by the virus.

1 Jul 2020

Sanford Burnham Prebys announces research agreement with Lilly to characterize COVID-19 antibodies

Sanford Burnham Prebys Medical Discovery Institute today announced a research agreement with Eli Lilly and Company (Lilly) to characterize Lilly's next-generation anti-SARS-CoV-2 antibodies.

30 Jun 2020

Princeton researcher solves long-standing mysteries of membrane protein structure

Ion channels and membrane transporters are in the business of moving ions and small molecules across cellular membranes. They are essential for metabolic and cellular homeostasis, and for a host of biological signaling pathways.

30 Jun 2020

Researchers discover receptor that regulates aging effects in mice

Increasing abdominal girth and shrinking muscles are two common side effects of aging. Researchers at the University of Bonn have discovered a receptor in mice that regulates both effects.

26 Jun 2020

New approach spurs production of antibiotic or antiparasitic compounds in bacteria

Researchers have developed a method to spur the production of new antibiotic or antiparasitic compounds hiding in the genomes of actinobacteria, which are the source of drugs such as actinomycin and streptomycin and are known to harbor other untapped chemical riches.

26 Jun 2020

Receptor News and Research

Single-nucleus RNA sequencing helps compare transcriptional responses to acute cocaine

Metabolomics can help understand the impact of calorie-restricted diets on aging

Structural analysis of SARS-CoV-2 spike protein offers clues about the virus' evolution

Study shows engineered natural killer immune cells can directly kill tumor cells

BU researchers develop new way to better understand human cell communication

Organoids reveal inflammatory processes that play a role in infectious diseases

Researchers track how key brain receptor works

Engineered T-cells attack solid-tumor cancer cells from humans and mice

Lab-grown 'mini-brains' can be infected by SARS-CoV-2 virus

COVID-19 virus can infect heart cells in a lab dish, study shows

Sanford Burnham Prebys announces research agreement with Lilly to characterize COVID-19 antibodies

Princeton researcher solves long-standing mysteries of membrane protein structure

Researchers discover receptor that regulates aging effects in mice

New approach spurs production of antibiotic or antiparasitic compounds in bacteria

Angpt2 hormone can help treat obesity-induced metabolic disorders

Molecular dynamic simulations may contribute to structure-based drug design

Study identifies complex functional, physical interactions between p53 gene and the INSR pathway

Blocking A 'Jamming Signal' Can Unleash Immune System To Fight Tumors

Chemist Develops Potential Drug To Treat Type 2 Diabetes Without Harsh Side Effects

CAR T Cell Therapy: Potential For Considerable Savings

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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