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Novel gene therapy offers hope to children with genetic, neurodegenerative diseases

Newly devised gene therapy can help children born with AADC, a rare genetic disorder that causes developmental and physical disabilities.

13 Jul 2021

Liver fibrosis might be treatable with selective immunotoxins

Chronic alcohol abuse and hepatitis can injure the liver and lead to fibrosis, the buildup of collagen and scar tissue. As a potential approach to treating liver fibrosis, University of California San Diego School of Medicine researchers and their collaborators are looking for ways to stop liver cells from producing collagen.

13 Jul 2021

Children with rare genetic disorder experience dramatic improvements in a gene therapy trial

Children with a devastating genetic disorder characterized by severe motor disability and developmental delay have experienced sometimes dramatic improvements in a gene therapy trial launched at UCSF Benioff Children's Hospitals.

13 Jul 2021

Study reveals how fine-tuning the immune system can improve vaccines, reduce disease severity

Immunologists have discovered a molecular route that regulates how crucial immune cells evolve into the immune system’s functioning components.

9 Jul 2021

Lipidomics study reveals schizophrenic patients’ resistance to antipsychotic drugs

Scientists discovered 22 lipids in the blood plasma of schizophrenia patients that were linked to slower symptom improvement over time.

8 Jul 2021

Researchers analyze and describe immune cells in the human bile duct

The immune cells that reside in the human bile duct have been studied and described in depth by researchers at Karolinska Institutet.

25 Jun 2021

Kirigami-inspired stent could deliver drugs to tubular organs

Inspired by kirigami, the Japanese art of folding and cutting paper to create three-dimensional structures, MIT engineers and their collaborators have designed a new type of stent that could be used to deliver drugs to the gastrointestinal tract, respiratory tract, or other tubular organs in the body.

From Massachusetts Institute of Technology (MIT) 15 Jun 2021

New research focuses on possible treatment options for childhood brain cancer

Medulloblastoma is a rare but devastating childhood brain cancer. This cancer can spread through the spinal fluid and be deposited elsewhere in the brain or spine.

11 Jun 2021

SARS-CoV-2 virus does not spread on hospital surfaces

By observing what was going on across the world in early 2020, researchers from the University of California San Diego School of Medicine knew that their region will soon be flooded with patients infected with COVID-19—the disease caused by the coronavirus, SARS-CoV-2.

From UC San Diego 11 Jun 2021

Consuming large amounts of daily caffeine may increase the risk of glaucoma

Consuming large amounts of daily caffeine may increase the risk of glaucoma more than three-fold for those with a genetic predisposition to higher eye pressure according to an international, multi-center study.

8 Jun 2021

New insights on how synovial sarcoma develops and spreads

A new study published today in Cancer Discovery, a journal of the American Association for Cancer Research, reports findings that may change the understanding of how synovial sarcoma develops and spreads.

7 Jun 2021

Immunotherapy following kidney cancer surgery prolonged disease-free survival rates

Treatment with an immunotherapy drug following kidney cancer surgery, prolonged disease-free survival rates in patients at high risk for recurrence, according to an interim report of a phase 3 clinical trial of adjuvant immunotherapy in this patient population.

4 Jun 2021

Immune therapy after surgery reduces recurrence risk in patients with high-risk melanoma

Patients with high-risk melanoma who had a course of pembrolizumab after their surgery had a longer time before their disease recurred than patients who got either ipilimumab or high-dose interferon after surgery. These findings of a large SWOG Cancer Research Network clinical trial, S1404, will be presented at the ASCO annual meeting June 6, 2021.

4 Jun 2021

Some Type 2 diabetes patients could benefit from bone marrow stem cell transplants, study shows

Type 2 diabetes patients who are not overweight and who have had the disorder for less than a decade can benefit from stromal stem cells transplanted from their own bone marrow, according to a study published today in STEM CELLS Translational Medicine.

4 Jun 2021

News study may lead to future therapeutic strategies against obesity, diabetes

The gut and the brain communicate with each other in order to adapt satiety and blood sugar levels during food consumption. The vagus nerve is an important communicator between these two organs.

3 Jun 2021

Scientists develop new method that enables single-cell RNA sequencing in large number of cells

RNA sequencing is a powerful technology for studying cells and diseases. In particular, single-cell RNA sequencing helps uncover the heterogeneity and diversity of our body.

2 Jun 2021

New study shows why some children get secondary leukemia after neuroblastoma treatment

Researchers from the Wellcome Sanger Institute and the University of Cambridge discovered that in children with neuroblastoma—a tumor of immature nerve cells—platinum chemotherapy created mutations in the genome that might lead to leukemia in some children later on.

31 May 2021

More informed choices of contraceptives can prevent breast cancer

Hormonal contraceptives, e.g. the pill, the patch, and the vaginal ring, contain synthetic hormones that prevent pregnancy by either stopping ovulation, changing the cervical mucus to stop sperm from passing through the cervix and finding an egg, or changing the womb's lining to prevent a fertilized egg from being implanted in it.

31 May 2021

Neuromorphic chip recognizes complex biosignals, can help monitor epilepsy

Current neural network algorithms produce impressive results that help solve an incredible number of problems.

27 May 2021

Latest articles provide novel insights into the mechanisms driving pridopidine neuroprotective effects

Prilenia Therapeutics B.V., a clinical stage biotech company focused on developing novel treatments for neurodegenerative and neurodevelopmental disorders, today announces the publication of three peer-reviewed journal articles, highlighting key aspects of the mechanism of action of its lead asset, pridopidine, and the importance of S1R activation as a mechanism to attenuate biological features of neurodegenerative diseases.

25 May 2021

Hospital News and Research

Novel gene therapy offers hope to children with genetic, neurodegenerative diseases

Liver fibrosis might be treatable with selective immunotoxins

Children with rare genetic disorder experience dramatic improvements in a gene therapy trial

Study reveals how fine-tuning the immune system can improve vaccines, reduce disease severity

Lipidomics study reveals schizophrenic patients’ resistance to antipsychotic drugs

Researchers analyze and describe immune cells in the human bile duct

Kirigami-inspired stent could deliver drugs to tubular organs

New research focuses on possible treatment options for childhood brain cancer

SARS-CoV-2 virus does not spread on hospital surfaces

Consuming large amounts of daily caffeine may increase the risk of glaucoma

New insights on how synovial sarcoma develops and spreads

Immunotherapy following kidney cancer surgery prolonged disease-free survival rates

Immune therapy after surgery reduces recurrence risk in patients with high-risk melanoma

Some Type 2 diabetes patients could benefit from bone marrow stem cell transplants, study shows

News study may lead to future therapeutic strategies against obesity, diabetes

Scientists develop new method that enables single-cell RNA sequencing in large number of cells

New study shows why some children get secondary leukemia after neuroblastoma treatment

More informed choices of contraceptives can prevent breast cancer

Neuromorphic chip recognizes complex biosignals, can help monitor epilepsy

Latest articles provide novel insights into the mechanisms driving pridopidine neuroprotective effects

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