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Cells within the center of a tumor have the highest chance of spreading around the body

Researchers from the Francis Crick Institute, Royal Marsden, UCL and Cruces University Hospital have found that cells from different parts of kidney tumors behave differently, and surprisingly, cells within the center of a tumor are the most aggressive and have the highest chance of spreading around the body.

18 May 2021

Epigenetic changes drive the fate of a B cell

B cells are the immune cells responsible for creating antibodies, and most B cells produce antibodies in response to a pathogen or a vaccine, providing immunity.

14 May 2021

Food dyes may cause disease when the immune system is dysregulated

Artificial food colorants can cause disease when the immune system has become dysregulated, Icahn School of Medicine at Mount Sinai researchers report.

14 May 2021

Ulsan genome project reaches milestone of sequencing 10,000 whole genomes

UNIST and Ulsan City officially announced that their ambitious 10,000 Genome Project has finally reached the milestone of sequencing 10,000 whole genomes. On this day, they also held a declaration ceremony to commemorate the successful completion of the Ulsan 10,000 Genome Project, which was initiated in 2016 as part of the Genome Korea in Ulsan Project launched in 2015.

11 May 2021

New method can enable early detection and treatment of cerebral aneurysms

Cerebral aneurysms are malformations caused by abnormalities on the walls of blood vessels in the brain. When these blood vessels rupture, about 30% of the sufferers die on the spot, giving these the rightful label of 'ticking bombs in the head'.

11 May 2021

Mutations in GEMIN5 protein can cause rare genetic disorders in children

Researchers have discovered a genetic cause of an unusual neurological disorder characterized by developmental delay, known as ataxia.

From University of Pittsburgh 10 May 2021

Lack of functional GAS2 gene causes severe hearing impairment in mice

A gene called GAS2 plays a key role in normal hearing, and its absence causes severe hearing loss, according to a study led by researchers in the Perelman School of Medicine at the University of Pennsylvania.

10 May 2021

Highly efficient method to identify the genetic “switches” that control gene expression

Scientists have created a high-throughput method to help explain and regulate gene expression for the treatment of diseases like beta-thalassemia and sickle cell disease.

7 May 2021

Study defines genetic positions associated with the progression of Parkinson’s disease

The progression of Parkinson’s disease (PD) is an important factor in patients’ well-being and clinical trials.

7 May 2021

Study shows potential of human mesenchymal stem cells in treating NTM lung infection

A study released today in STEM CELLS Translational Medicine offers hope for those suffering from a chronic, difficult to treat condition called non-tuberculous mycobacteria (NTM) lung infection.

5 May 2021

New therapeutic target for patients with acute myeloid leukemia

According to a new study, targeting a pathway that is critical for the survival of some cases of acute myeloid leukemia could open up a new therapeutic route for patients.

3 May 2021

Distinctive "spike" proteins of SARS-CoV-2 also play a key role in the disease

Scientists have known for a while that SARS-CoV-2's distinctive "spike" proteins help the virus infect its host by latching on to healthy cells.

3 May 2021

New gene editing tool helps analyze the mysterious quirk of bacteria

While the CRISPR-Cas9 gene editing system has become the poster child for innovation in synthetic biology, it has some major limitations.

3 May 2021

Researchers identify specific proteins that play a key role in the development of dendritic cells

The human immune system comprises functionally specialized cellular defense mechanisms that protect the body against disease.

3 May 2021

New integrative genetic screening technology offers insights into role of DNA accessibility in cancer

In a new resource for the scientific community, published today in Nature Biotechnology, researchers in the lab of Neville Sanjana, PhD, at the New York Genome Center (NYGC) and New York University (NYU) developed CRISPR-sciATAC, a novel integrative genetic screening platform that jointly captures CRISPR gene perturbations and single-cell chromatin accessibility genome-wide.

30 Apr 2021

Geisinger receives $3.6 million from NCI to study the role of genetic variation in cancer

The National Cancer Institute, part of the National Institutes of Health, has awarded a 5-year, $3.6 million contract to Geisinger to study the role of genetic variation in cancer.

30 Apr 2021

Researchers hope to make estrogen therapy a more accessible treatment for breast cancer patients

Researchers at Dartmouth's and Dartmouth-Hitchcock's Norris Cotton Cancer Center (NCCC) hope to make estrogen therapy a more accessible treatment option for breast cancer patients who could benefit from it.

26 Apr 2021

Small molecular changes can have dramatic impact on the CAR T cell function

When researchers from Penn Medicine found that many patients with B-cell acute lymphoblastic leukemia (ALL) treated with the investigational chimeric antigen receptor (CAR) T cell therapy targeting the CD22 antigen didn't respond, they went back to the drawing board to determine why.

23 Apr 2021

SARS-CoV-2 infection produces antibodies that can destroy infected cells

Research teams investigated the antibodies generated in people with symptomatic or asymptomatic SARS-CoV-2 infection.

From Institut Pasteur 23 Apr 2021

Researchers uncover a key genetic culprit in the development of acute lymphoblastic leukemia

Using a widely known field of mathematics designed mainly to study how digital and other forms of information are measured, stored and shared, scientists at Johns Hopkins Medicine and Johns Hopkins Kimmel Cancer Center say they have uncovered a likely key genetic culprit in the development of acute lymphoblastic leukemia (ALL).

21 Apr 2021

Hospital News and Research

Cells within the center of a tumor have the highest chance of spreading around the body

Epigenetic changes drive the fate of a B cell

Food dyes may cause disease when the immune system is dysregulated

Ulsan genome project reaches milestone of sequencing 10,000 whole genomes

New method can enable early detection and treatment of cerebral aneurysms

Mutations in GEMIN5 protein can cause rare genetic disorders in children

Lack of functional GAS2 gene causes severe hearing impairment in mice

Highly efficient method to identify the genetic “switches” that control gene expression

Study defines genetic positions associated with the progression of Parkinson’s disease

Study shows potential of human mesenchymal stem cells in treating NTM lung infection

New therapeutic target for patients with acute myeloid leukemia

Distinctive "spike" proteins of SARS-CoV-2 also play a key role in the disease

New gene editing tool helps analyze the mysterious quirk of bacteria

Researchers identify specific proteins that play a key role in the development of dendritic cells

New integrative genetic screening technology offers insights into role of DNA accessibility in cancer

Geisinger receives $3.6 million from NCI to study the role of genetic variation in cancer

Researchers hope to make estrogen therapy a more accessible treatment for breast cancer patients

Small molecular changes can have dramatic impact on the CAR T cell function

SARS-CoV-2 infection produces antibodies that can destroy infected cells

Researchers uncover a key genetic culprit in the development of acute lymphoblastic leukemia

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