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Genetically engineered immune cells deliver anticancer signal to organs to prevent metastasis

Scientists have genetically engineered immune cells, called myeloid cells, to precisely deliver an anticancer signal to organs where cancer may spread.

From National Cancer Institute (NCI) 25 Mar 2021

Monitoring pollen levels using environmental DNA

In this interview, AZoLifeSciences speaks to Dr. Ben Wheeler about his latest research and how we monitor pollen levels using environmental DNA.

From University of Exeter 25 Mar 2021

Gender difference accounts for major psychiatric disorders

According to an analysis of sex variations in the genetics of bipolar disorder, schizophrenia, and major depressive disorders.

24 Mar 2021

New function of BMI1 gene can protect against Alzheimer’s disease

The Maisonneuve-Rosemont Hospital Research Centre has taken another step toward interpreting Alzheimer’s disease.

24 Mar 2021

Stem cell therapy could help restore debilitating muscle loss that happens with age

As the name implies, induced pluripotent stem cells can become any type of cell in our body, and scientists have evidence that when they prompt them to become muscle progenitor cells they can help restore the sometimes debilitating muscle loss that happens with age.

24 Mar 2021

Nutritional supplement may reduce the risk of strokes caused by a rare genetic disorder

Researchers from Children's Hospital of Philadelphia (CHOP) have discovered that a widely used nutritional supplement may significantly reduce the risk of fatal strokes caused by a rare genetic disorder.

24 Mar 2021

Hormone drugs may help disarm coronavirus spike protein and stop disease progression

Hormone drugs that reduce androgen levels may help disarm the coronavirus spike protein used to infect cells and stop the progression of severe COVID-19 disease, suggests a new preclinical study from researchers in the Abramson Cancer Center at the University of Pennsylvania and published online in Cell Press's iScience.

23 Mar 2021

“Hidden genetic defects” can cause a variety of illnesses in children

For the first time, scientists have gained a better understanding of the “hidden genetic defects” of the general population in Europe.

22 Mar 2021

New genetic engineering strategy largely reduces tau protein levels in Alzheimer’s animal model

A genetic engineering approach has helped scientists to drastically decrease the levels of tau protein.

22 Mar 2021

Study identifies new biomarkers for the prognosis of gastric adenocarcinoma

A study headed by UCM reports that polymorphisms in gene TGFB1 and low plasma levels of protein TGFB1 serve as biomarkers for the gastric adenocarcinoma prognosis.

19 Mar 2021

Study shows beneficial effects of gene therapy can be observed even after several decades

A new study shows that the advantageous effects of gene therapy can be observed several decades after the body clears the transplanted blood stem cells.

From University College London 18 Mar 2021

New highly sensitive RNA detection method advances in situ transcriptomics

Human cells typically transcribe half of their roughly 20,000 genes into RNA molecules at any given time. Just like with proteins, the function of those RNA species not only relies on their abundance but also their precise localization within the 3D space of each cell.

18 Mar 2021

Scientists provide a complete phenotypic landscape of SCN2A-related disorders

Researchers from Children's Hospital of Philadelphia (CHOP) affiliated with the CHOP Epilepsy Neurogenetics Initiative (ENGIN) have compiled a complete genetic and clinical analysis of more than 400 individuals with SCN2A-related disorder, which has been linked to a variety of neurodevelopmental disorders, including epilepsy and autism.

18 Mar 2021

Genetic flaw shows promise for treating eye disease

A genetic flaw may hold the key to delay or prevent the onset of a serious eye disorder that can result in blindness and vision loss.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 17 Mar 2021

Study reveals substantial difference in selection and timing of genetic tests for non-small-cell lung cancer

During biomarker testing, certain disease-associated molecules are examined to estimate the progression of a disease and its response to treatments.

17 Mar 2021

Environmental DNA could help better understand grasses that cause allergies

Pollen from grass is a significant outdoor allergen that causes widespread and expensive respiratory conditions, such as hay fever (rhinitis) and allergic asthma.

15 Mar 2021

RNA-editing events can reveal the genetic basis of many human diseases

Scientists from CHOP have detected RNA-editing events that affect the expression of genes and the phenotypic manifestation of that specific expression.

10 Mar 2021

Study demonstrates the contagion effect of weight loss program in relatives of participants

People living with a patient undergoing an intensive weight loss treatment also benefit from this therapy.

10 Mar 2021

New technique can mitigate the effects of brain injury in preterm babies

One in 10 babies are born prematurely in the United States, leading to complications that can impact the infants’ locomotor development and affect basic tasks.

9 Mar 2021

Immune cells in cerebrospinal fluid could be biomarkers to predict immunotherapy response

Results from a study led by Joan Seoane, Director of Preclinical and Translational Research co-program at VHIO and ICREA Professor, show that immune cells accessing cerebrospinal fluid faithfully recapitulate the characteristics of cells identified in brain metastasis, and could therefore constitute novel biomarkers of response to immune-based therapies.

9 Mar 2021

Hospital News and Research

Genetically engineered immune cells deliver anticancer signal to organs to prevent metastasis

Monitoring pollen levels using environmental DNA

Gender difference accounts for major psychiatric disorders

New function of BMI1 gene can protect against Alzheimer’s disease

Stem cell therapy could help restore debilitating muscle loss that happens with age

Nutritional supplement may reduce the risk of strokes caused by a rare genetic disorder

Hormone drugs may help disarm coronavirus spike protein and stop disease progression

“Hidden genetic defects” can cause a variety of illnesses in children

New genetic engineering strategy largely reduces tau protein levels in Alzheimer’s animal model

Study identifies new biomarkers for the prognosis of gastric adenocarcinoma

Study shows beneficial effects of gene therapy can be observed even after several decades

New highly sensitive RNA detection method advances in situ transcriptomics

Scientists provide a complete phenotypic landscape of SCN2A-related disorders

Genetic flaw shows promise for treating eye disease

Study reveals substantial difference in selection and timing of genetic tests for non-small-cell lung cancer

Environmental DNA could help better understand grasses that cause allergies

RNA-editing events can reveal the genetic basis of many human diseases

Study demonstrates the contagion effect of weight loss program in relatives of participants

New technique can mitigate the effects of brain injury in preterm babies

Immune cells in cerebrospinal fluid could be biomarkers to predict immunotherapy response

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