Apoptosis News and Research

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Apoptosis is programmed cell death, the body's normal method of disposing of damaged, unwanted, or unneeded cells.

Light-induced cellular apoptosis method can kill diseased cells without causing adverse reactions

Cancer has been the leading cause of death in Japan over the past 40 years. Despite the rise in patients due to the aging population, progresses in diagnosis and treatment are leading to higher survival rates.

1 Apr 2022

Study shows that mechanical stress help cancer cells metastasize

A recent study shows that compressing cancer cells through tight spaces makes them more violent and helps them avoid cell death.

9 Mar 2022

Protein appears key to the function and survival of brain cells most impacted by glaucoma

A ubiquitous protein called sigma 1 receptor, which is known to protect cells from stress, appears key to the function and survival of the neurons most impacted by glaucoma, scientists report.

2 Mar 2022

Scientists elucidate mechanism that causes treatment resistance in aggressive pancreatic cancer

Drug resistance is a major obstacle in the treatment of cancers. In an aggressive type of pancreatic cancer, for instance, drug resistance is associated with the suppression of programmed cell death, which results in the uncontrolled growth of cancer cells.

25 Feb 2022

Study findings open new avenues for research into host-directed therapies for TB

A*STAR’s GIS and ID Labs have discovered KCNJ15, a gene linked to the human immune system’s ability to combat TB and maybe other infectious diseases.

18 Feb 2022

Experts trigger apoptosis in leukemia cells by disrupting their energy maintenance mechanism

A group of researchers from UNIGE in Switzerland and Inserm in France has discovered a previously unknown process that could lead to the creation of novel medicines.

18 Feb 2022

Study reveals how the body controls inflammation during removal of damaged cells

A research team from Cologne and Osnabrück has investigated in detail how messenger substances signal inflammation during the removal of damaged cells in the body.

7 Feb 2022

Label-free device enables in-situ tracking of cell development and maturation

The biological intracellular microenvironment is diverse, consisting of several cell compartments and intracellular components.

20 Jan 2022

New finding could lead to the development of cell death regulators for cancer therapies

Scientists led by Professor Ana J. Garcia-Saez at the CECAD Cluster of Excellence for Aging Research at the University of Cologne have shown that apoptosis, the programmed cell death, involves a direct physical interplay between the two proteins BAX and DRP1.

17 Jan 2022

Simple, marine-dwelling creature shines light on cancer resistance

A simple, marine-dwelling creature known as Trichoplax adhaerens has some remarkable properties. The organism can tolerate unusually high doses of radiation that would kill most other forms of life. T. adhaerens has another intriguing characteristic: the ability to resist cancer.

24 Dec 2021

Study identifies novel function for existing protein

Researchers recently identified a new role of the protein tBID, which was to date linked to the regulatory role in cancer and cell death. But tBID also directly mediates apoptosis (controlled cell death).

23 Dec 2021

Study uncovers mechanism that triggers cancer cell death

Scientists recently pinpointed the mechanism by which inhibitors of the ERK5 protein kinase diminish cancer cell proliferation and trigger their death.

23 Dec 2021

Review: Transmission, origin, pathogenesis, animal model and diagnosis of Zika virus

Announcing a new article publication for Zoonoses journal. Dallas Vue and Qiyi Tang from Howard University College of Medicine, Washington, DC, USA review transmission, origin, pathogenesis, animal model and diagnosis of Zika Virus.

10 Dec 2021

Apoptosis of mesenchymal stromal cells benefits therapeutic function

Scientists recently identified the therapeutic benefits to patients receiving mesenchymal stromal cell (MSC) therapy.

15 Nov 2021

Researchers propose novel model for mitochondrial nucleoid self-assembly

Mitochondria, the powerhouse of mammalian cells, also perform vital roles in cell signaling, cell metabolism, and apoptosis.

8 Nov 2021

Research uncovers key component of cellular malfunction that contributes to tumor growth

Scientists have homed in on a crucial step within the sequence of chemical reactions that govern regulation of cell division, proliferation and death, and whose malfunction contributes to the growth of tumors.

3 Nov 2021

Key networks controlling pluripotency and apoptosis during development revealed

During the early stages of human embryonic development, a small collection of cells called human embryonic stem cells co-ordinates growth and differentiation finally giving rise to highly specialized human tissues.

1 Nov 2021

Mitochondrial inner membrane fusion protein acts as a molecular chaperone

Cells contain numerous functional “micro-organs” known as organelles. Mitochondria, the “power plant” of the cell, are the energy-producing organelles.

25 Oct 2021

Study imparts mechanistic understanding on early stages of human cancer

Scientists demonstrated that normal human fibroblast cells can be converted to specific cancer cells through factors that are identified in actual human patients.

9 Sep 2021

Study details the role of PANoptosome in activating innate immune response

Immunologists discovered how immune sensors in infected cells organize and initiate an immune response to infections with living bacteria and viruses.

3 Sep 2021