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Study Expands Potential of Retrons for DNA Editing

Within bacterial cells, specialized immune systems known as retrons fend off viral attacks. But that's not all they can do.

18 Sep 2024

Membrane Tension and Calcium Signaling Regulate Phospholipid Scrambling

Researchers at the Institute for Integrated Cell-Material Sciences (WPI-iCeMS) at Kyoto University have discovered new information regarding how cells control the distribution of lipids in their cell membrane.

16 Sep 2024

Potassium Isotope Ratios: A Potential Biomarker for Early Alzheimer's Disease Diagnosis

Potassium isotope ratios in serum show promise as biomarkers for Alzheimer's disease, revealing significant differences between patients and healthy controls.

16 Sep 2024

CRISPR and Antibodies Offer New Hope for Improving CAR-T Cell Therapy Outcomes

Mayo Clinic researchers mined the molecular foundations of cancer and uncovered a new reason chimeric antigen receptor (CAR-T cell therapy) fails in some patients.

13 Sep 2024

A Powerful New Tool for Biomedical Research

Scientists at Weill Cornell Medicine in Qatar (WCM-Q) have built a comprehensive molecular map of the human body and its complicated physiological processes by analyzing thousands of molecules found in 391 volunteers' blood, urine, and saliva samples.

12 Sep 2024

A New Approach to Understanding Enhancer-TF Interactions

Every cell in the human body has the same DNA, yet liver cells differ from brain cells, and skin cells from muscle cells.

9 Sep 2024

SGLT-2 Inhibitors May Lower Dementia Risk in Type 2 Diabetes Patients, Study Finds

A study reveals SGLT-2 inhibitors significantly reduce dementia risk in type 2 diabetes patients, with effects strengthening over longer treatment durations.

9 Sep 2024

LSTM Research Identifies 91 RNA Viruses in Parasitic Worms

New research shows that parasitic nematodes, responsible for infecting more than a billion people globally, carry viruses that may solve the puzzle of why some cause serious diseases.

5 Sep 2024

Atypical B Cells Play a Central Role in COVID-19 Vaccine Response

Vaccines function by strengthening defenses against viruses that invade human bodies. Vaccination against COVID-19 teaches the human immune system's specialized B cells how to identify the virus.

5 Sep 2024

Inflammation-Induced Epigenetic Changes Limit Intestinal Stem Cell Regeneration

Researchers from the University of Michigan, Baylor College of Medicine, and other affiliated institutions have found that intestinal stem cells (ISCs) are permanently altered by inflammation in the gut, which limits the cells' capacity to repair the gut even after the inflammation has subsided.

4 Sep 2024

Beta Cells Alone Can Maintain Glycemic Balance Without Other Pancreatic Cells

Our glycemic balance is based on the ability of the pancreatic beta cells to detect glucose and secrete insulin to maintain our blood sugar levels.

4 Sep 2024

Genetic Variants Linked to Rare Bicuspid Aortic Valve Disease Identified

Genetic variants linked to a rare form of bicuspid aortic valve disease that affects young adults and can lead to dangerous and potentially life-threatening aortic complications have been identified by researchers at UTHealth Houston.

3 Sep 2024

Melbourne Researchers Achieve Breakthrough in Creating Human-Like Blood Stem Cells

Melbourne researchers have made a world first breakthrough into creating blood stem cells that closely resemble those in the human body.

3 Sep 2024

Single-Cell Sequencing Reveals Mechanism of Coronary Artery Formation

The process by which new arteries develop in the heart has been clarified by a group under the direction of Dr. Elena Cano at the Integrative Vascular Biology Lab of Professor Holger Gerhardt at the Max Delbrück Center in Berlin.

2 Sep 2024

Study Identifies Genes for Healthier Rice with Low Glycemic Index and High Protein

A team of researchers at the International Rice Research Institute (IRRI) has identified genes and markers responsible for low glycemic index (GI) and high protein content in rice, using genetics and artificial intelligence classification methods.

2 Sep 2024

New Insights into Mosquito Mating Could Enhance Malaria Control Strategies

A high-pitched buzzing sound in your ear is an unmistakable sign that a female mosquito is out on the hunt -; for they, not males, drink blood. Hearing that tone might make you turn to try to swat the pest. But for a male mosquito, that tone means it's time to mate.

2 Sep 2024

Marmosets Use Vocal Calls to Name Each Other, Study Reveals

In a groundbreaking discovery, researchers from Hebrew University have found that marmoset monkeys use specific vocal calls, called "phee-calls," to identify and communicate with each other. This ability to vocally label others has only been seen in humans, dolphins, and elephants until now.

30 Aug 2024

Evolution of Blood Sugar Regulation in Neotropical Bats

Humans must regulate blood sugar concentrations to stay healthy and to fuel our cells. Too little or too much can cause serious health complications, and high blood sugar is a hallmark of the metabolic condition, diabetes. New research from the Stowers Institute for Medical Research may enable potential solutions to metabolic disease by turning to evolution and to bats.

29 Aug 2024

Clock Genes Drive Evolutionary Split in Two Moth Species

Investigating moth speciation, this research highlights the impact of clock genes on behavior, providing a rare glimpse into evolutionary processes.

28 Aug 2024

New Human Intestinal Immuno-Organoids Reveal Insights into Immune Cell Dynamics and Cancer Immunotherapy

Research on intestinal immuno-organoids reveals their potential in modeling immune interactions and studying intestinal diseases linked to cancer therapies.

26 Aug 2024