Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

U of T Researchers Develop Groundbreaking Platform for Protein-Based Disease Treatment

Researchers at the University of Toronto and Sinai Health have created a new platform to identify proteins that can be co-opted to control the stability of other proteins -; a new but largely unrealized approach to the treatment of disease.

25 Mar 2024

UT Southwestern Unveils New Method for Fighting Complex Infections

Treating complex bacterial infections with customized therapies tailored to the infection and the patient is closer to reality, thanks to researchers at UT Southwestern Medical Center.

22 Mar 2024

Metrion Biosciences Strengthens Team with Three Key Appointments

Metrion Biosciences Limited (“Metrion”), the specialist ion channel contract research organisation (CRO) and drug discovery company, has promoted Clare Rutty to CFO and welcomes two new hires in Sue Peffer as Head of Marketing and Leanne Clarke as HR Officer.

12 Mar 2024

Breakthrough Studies Shed Light on Origins of Homochirality in Biology

Molecules often have a structural asymmetry called chirality, which means they can appear in alternative, mirror-image versions, akin to the left and right versions of human hands.

29 Feb 2024

New "Tissue-in-a-CUBE" Offers Alternative to Animal Testing in Drug Development

A research team at the RIKEN Center for Biosystems Dynamics Research (BDR) in Japan has succeeded in establishing a model of the blood-brain barrier using modularized tissue derived from human cells.

29 Feb 2024

AI's Impact on Protein Function Prediction Revealed

Researchers may be able to learn more about the inner workings of cells with the aid of a novel artificial intelligence (AI) technology that makes logical deductions regarding the function of unidentified proteins.

15 Feb 2024

Dr. Bartek Rajwa of Purdue University Named Editor-in-Chief of “Cytometry Part A” Journal by the International Society for Advancement of Cytometry

The International Society for Advancement of Cytometry (ISAC) is pleased to announce the appointment of Dr. Bartek Rajwa as the new Editor-in-Chief of “Cytometry Part A – the Journal of Quantitative Cell Science.”

10 Feb 2024

Aspen Biosciences Launches Pipeline, The Program Management Software Platform Specifically for Drug Discovery. The Groundbreaking ‘Pipeline’ Platform is Now Available for Therapeutics Development Teams

Aspen Biosciences, a leading provider of custom software, and integrations for drug discovery companies, is excited to announce the launch of Pipeline, the drug discovery program management software platform.

8 Feb 2024

ELRIG UK Announces Steve Bates and Dr Anderson Ryan as Keynote Speakers at Research and Innovation 2024

The European Laboratory Research & Innovation Group (ELRIG) UK today announced the keynote speakers for its upcoming Research and Innovation conference taking place at the University of Manchester from 20–21 March.

From ELRIG (UK) Ltd. 8 Feb 2024

From Lab Trials to Clinical Studies - Integrin αV's Role in Cancer Prognosis

Researchers at City of Hope, one of the biggest cancer research and treatment centers in the US, have identified a novel biological process that is critical to the pathogenic potential of cancer cells.

6 Feb 2024

SCIEX Expands High-Throughput Screening Solutions With Echo® MS+ System

SCIEX, a global leader in life science analytical technologies, launches the Echo® MS+ system at SLAS 2024.

From SCIEX 6 Feb 2024

Diagnostic Biochips: Brain Research Tools for the Future

In this interview, we delve into the innovative world of Diagnostic Biochips with its founder, Brian Jamieson. He shares insights into the company's inception, its contributions to advancing brain research, and the future of neural interfacing technology.

1 Feb 2024

Promising Drug Offers Hope for Overcoming Resistance to Protein Degraders

Protein degraders, a novel approach in drug discovery, show promise to tackle diseases previously thought to be untreatable.

31 Jan 2024

Formulatrix® and Olink® Announce Collaboration to Deliver Automated Proteomics Research Solutions to Enable Protein Detection with Exceptional Precision and Speed

Formulatrix, a leader in innovative automated liquid handling technologies, announced a multi-year collaboration and supply agreement to advance the automation of Olink’s PEA (Proximity Extension Assay) technology, including the Target 96, Target 48, Flex, and Explore workflows.

From FORMULATRIX 31 Jan 2024

Lunaphore and Acd Revolutionize Spatial Biology Research With the Launch of the First Fully Automated, Same-Section, Hyperplex Multiomics Application

Bio-Techne Corporation (NASDAQ: TECH) today announced that its spatial biology brands, Lunaphore and Advanced Cell Diagnostics (ACD), will launch the first fully automated spatial multiomics workflow with same-section hyperplex detection of RNA and protein biomarkers.

From Bio-Techne 25 Jan 2024

Revolutionizing Drug Discovery with Novel Sulfur Compound Synthesis

Over the past decade, there has been significant progress in the development of novel sulfur-containing compounds utilized across diverse industries, including pharmaceuticals and agricultural products.

23 Jan 2024

Stem Cell-Derived Brain Organoids on Ax-3 Mission Seek to Improve Modeling for Neurodegenerative Diseases

More than 5 million people worldwide are living with neurodegenerative disorders like Parkinson’s disease and primary progressive multiple sclerosis (PPMS).

19 Jan 2024

Commercializing Innovation in a Life Sciences Ecosystem

In this interview, Glennis Mehra, the Director of BioLabs at NYU Langone, shares her journey through the life sciences industry and delves into the role of BioLabs as an incubator for early-stage life science companies.

17 Jan 2024

Algal Blooms May Pose More Health Risks Than Previously Thought

Florida's 156-mile-long Indian River Lagoon (IRL) borders five different counties and has five inlets that connect the lagoon with the Atlantic Ocean.

16 Jan 2024

Breakthrough 3D Vascular Sheet Mimics Atherosclerosis for High-Throughput Drug Screening

A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease, University of Alabama at Birmingham researchers report in the journal Biomaterials.