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Molecular Mechanisms That Maintain the Tissue Specificity of PKMzeta

The protein PKMzeta has been strongly associated with long-term memory formation.

19 Apr 2023

UConn Health scientists explain why Shigella bacteria can infect humans but not mice

Shigella bacteria can infect humans but not mice. In the March 29 issue of Nature, a team from UConn Health explains why. Their findings may explain the multifariousness of a key weapon of our immune system.

31 Mar 2023

Common Epstein-Barr virus may be a trigger for multiple sclerosis

In 1868, French physician Jean-Martin Charcot, known as the founder of modern neurology, defined a disease entity in which multiple plaques formed in the brain and spinal cord, with varying physical symptoms, called Sclérose en plaques, or in English as multiple sclerosis (MS).

24 Mar 2023

Wearable microscopes produce real-time images of mouse spinal cord activity

The spinal cord acts as a messenger, carrying signals between the brain and body to regulate everything from breathing to movement.

23 Mar 2023

Curcumin could enhance ovarian cancer treatments

A pharmacology researcher at New York Institute of Technology College of Osteopathic Medicine (NYITCOM) has co-authored a new study that makes a strong case for why a golden spice commonly found in curry could enhance ovarian cancer treatments.

23 Mar 2023

How can the adoption of AI technology accelerate drug discovery?

In this interview, we speak to SLAS 2023 keynote speaker Joshua Smith from IBM Research about the importance of AI in accelerating drug discovery.

From Society for Laboratory Automation and Screening (SLAS) 22 Mar 2023

Illumina launches its first product enabling long- and short-read sequencing on one instrument

Illumina Inc., a global leader in DNA sequencing and array-based technologies, today announced that its first product based on its novel Illumina Complete Long Read technology is now available to order.

22 Mar 2023

Uncovering the role of the third intracellular loop in the GPCR’s signaling mechanism

Over a one-third of FDA-approved drugs tend to function by targeting a G protein-coupled receptor, or so-called GPCR. The human body consists of over 800 kinds of GPCRs that offer cells with data concerning the external surrounding to calibrate responses.

20 Mar 2023

Researchers uncover the role of third intracellular loop in GPCR's signaling mechanism

More than a third of FDA-approved drugs work by targeting a G protein-coupled receptor, or GPCR. The human body has more than 800 types of GPCRs that provide cells with information about the external environment to calibrate responses.

20 Mar 2023

Study identifies previously unknown cell types that drive the onset of osteoarthritis

A Michigan Medicine study has identified a new potential target for treating osteoarthritis – a debilitating joint disease that affects over 31 million Americans and is a leading cause of disability worldwide.

10 Mar 2023

Study sheds light on unique processes that bestow naked mole-rats’ with eternal fertility

Unlike humans and other mammals, which become less fertile with age, naked mole-rats can reproduce throughout their remarkably long lifespans.

22 Feb 2023

Importance of drying temperature in the technological properties of OSPF

Orange, starchy sweet potatoes are great mashed, cut into fries or just roasted whole. But you likely haven't considered grinding them into a flour and baking them into your next batch of cookies -; or at least, not yet!

14 Feb 2023

UVA researchers discover a key trigger for common liver disease

University of Virginia School of Medicine researchers have discovered a key trigger for non-alcoholic fatty liver disease, a mysterious condition that causes fat to build up in the liver for no clear reason.

10 Feb 2023

New platform to study the feeding behavior of mosquitoes

If watching animals feast on human blood for 30-plus hours isn't your idea of fun, don't worry. The robot can do it.

10 Feb 2023

Synthetic biosensor could lead to better understanding of cell biology

A synthetic biosensor that mimics properties found in cell membranes and provides an electronic readout of activity could lead to a better understanding of cell biology, development of new drugs, and the creation of sensory organs on a chip capable of detecting chemicals, similar to how noses and tongues work.

8 Feb 2023

Long-term deep meditation may have a beneficial effect on gut microbiota, study suggests

Regular deep meditation, practised for several years, may help to regulate the gut microbiome and potentially lower the risks of physical and mental ill health, finds a small comparative study published in the open access journal General Psychiatry.

30 Jan 2023

New genetic condition that raises vulnerability to opportunistic infections

An international consortium co-led by Vanderbilt University Medical Center immunogeneticist Rubén Martínez-Barricarte, PhD, has discovered a new genetic disorder that causes immunodeficiency and profound susceptibility to opportunistic infections including life-threatening fungal pneumonia.

24 Jan 2023

New molecular profile of endometriosis to help improve therapeutic options

At Cedars-Sinai, a special and elaborate molecular profile of endometriosis has been engineered by investigators to help enhance therapeutic options for the millions of women suffering from the disease.

11 Jan 2023

Regeneration of the immune system in MS patients

Transplanting blood stem cells is a new but incredibly successful treatment for multiple sclerosis. Now, a study directed by the University of Zurich has looked closely at how the autoimmune disease is controlled by the treatment and how the immune system recovers afterward.

14 Nov 2022

Testing for residual solvents and terpenes in cannabis

AZoLifeSciences sat down with Tom Kwoka, Senior Application Scientist - GC/MS at PerkinElmer, and Alex Maitain, GC/MS Cannabis Analysis at PerkinElmer, to discuss the benefits of analyzing residual solvents and terpenes from cannabis and hemp products by Headspace GC/MS analysis.

From PerkinElmer 8 Nov 2022