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Targeting Long-read RNA Sequencing with Low-Cost Technology

Researchers at the Children’s Hospital of Philadelphia (CHOP) have created a flexible and affordable approach for targeted sequencing of full-length RNA molecules, which might hasten the development of novel diagnostics and therapies.

16 Aug 2023

Comprehensive “Super-Pangenome” for Watermelon Displays Potential

In terms of overall production and economic value, watermelon is an important agricultural commodity on a worldwide scale.

14 Aug 2023

Deciphering Buckwheat’s Genome to Improve Crop Yields

The high-precision chromosomal-level genome sequence of buckwheat has been decoded by a research group led by Kyoto University’s Graduate School of Agriculture, which is an important step toward unraveling the evolution of the buckwheat genome and the origins of the cultivated crop.

14 Aug 2023

Understanding Watermelon Genetics Could Lead to Development of More Resilient, Delicious Varieties

Watermelon is a globally significant agricultural product, both in terms of the total amount produced and the total economic value generated.

14 Aug 2023

A Surprisingly Quiet Discovery About Low-Noise Genes

While engaging in cell division research, Silke Hauf and members of her lab made a surprisingly quiet discovery.

11 Aug 2023

New Mechanism Regulating Tumor Growth in the Skeleton Identified

Tumor cells are known to be fickle sleeper agents, often lying dormant in distant tissues for years before reactivating and forming metastasis. Numerous factors have been studied to understand why the activation occurs, from cells and molecules to other components in the so-called tissue microenvironment.

11 Aug 2023

Researchers Lead Innovative Studies on Mammalian Aging and Life Span

Scientists at UCLA David Geffen School of Medicine and UCLA Health led an international research team that published two articles detailing changes in DNA – changes that researchers found are shared by humans and other mammals throughout history and are associated with life span and numerous other traits.

11 Aug 2023

Linking Alzheimer's Genetic Marker and Higher Female Fertility

The Apolipoprotein-ε4 (APOE-ε4) allele has been linked to an increased risk for several types of diseases in aging populations, particularly Alzheimer’s and cardiovascular disease.

10 Aug 2023

Hair Whorl Direction Influenced by Multiple Genes

The first gene mapping study on human scalp hair whorls not only demonstrates that hair whorl direction has a genetic basis but also that it is influenced by multiple genes.

10 Aug 2023

The “Unknome” Dataset Contains Protein Sequences That Are Still Unknown

Researchers from the UK anticipate that a new, freely accessible database they have developed will get smaller rather than bigger over time. This is due to the fact that it is a compilation of the many understudied proteins that are encoded by genes in the human genome, whose existence is recognized but whose activities are mostly unknown.

9 Aug 2023

New Discovery Leads to Underlying Factors to Gene Size Variations

The present understanding of genomic stability and variability is mostly based on a few model species, leaving the scope and generality of these discoveries uncertain.

9 Aug 2023

Researchers Find New Way to Defeat Gray Mold Without Toxic Chemicals

It's a mold that causes billions in crop losses every year, infecting berries, tomatoes and most other fruits and vegetables.

9 Aug 2023

Detection of Mutations in Children with Brain Tumors

Uppsala University researchers have devised a novel approach for detecting mutations in pediatric brain cancers.

8 Aug 2023

Bacteria Have Complex Circadian Clocks, Study Finds

Bacteria make up more than 10% of all living things but until recently we had little realization that, as in humans, soil bacteria have internal clocks that synchronize their activities with the 24-hour cycles of day and night on Earth.

7 Aug 2023

Researchers Elucidate STING Protein's New Role in Immune Defense

A signaling protein known as STING is a critical player in the human immune system, detecting signs of danger within cells and then activating a variety of defense mechanisms.

7 Aug 2023

Malaria Parasite’s Meiosis Could Hold the Key to New Treatments

Researchers from the Universities of Leicester and Nottingham have been awarded nearly £600,000 to investigate how sexual development and gene shuffling inside the malaria parasite can help regulate malaria transmission.

7 Aug 2023

RNA Modification in Driving Pancreatic Cancer Growth

RNA molecules can undergo chemical changes like m6A, which can have a significant influence on gene expression and affect several aspects of cancer development and progression

7 Aug 2023

New Insights Into How T Cells Become Exhausted in Cancer

Immune system T cells that should be able to kill cancer cells become dysfunctional or "exhausted" within hours of encountering a tumor, according to a study reported Aug. 3 in Nature Immunology.

7 Aug 2023

Beneficial Microbe Could be Effective Against Fungal Pathogens Wreaking Havoc on Golf Courses

There's a reason sports leagues from the pros on down use turfgrass. It is a hearty grass that can be mowed to exceedingly short heights and tolerates trampling foot traffic with ease.

4 Aug 2023

Determining a Network of Cellular Programs Controlling Human Cancers

A Ludwig Cancer Research study has identified a pair of genes whose expression by a type of immune cell within tumors is predictive of outcomes for cancer patients and is linked to a vast network of gene expression programs, engaged by multiple cell types in the tumor microenvironment, that control human cancers.

4 Aug 2023