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Cryo-EM imaging of STING protein reveals a new binding source for immune attacks

In new research, UT Southwestern scientists report that imaging a key immunity protein known as STING at near-atomic resolution reveals a previously undiscovered binding location that appears to be crucial for launching immunological attacks.

11 Apr 2022

Intracellular microbiota promote cell survival during tumor progression

Bacteria promote cancer metastasis by bolstering the strength of host cells against mechanical stress in the bloodstream, promoting cell survival during tumor progression, researchers report April 7th in the journal Cell.

8 Apr 2022

Specialist assay kits and microplates for cancer research

Porvair Sciences will exhibit its latest assay kits and microplates for cancer and life science research at the American Association for Cancer Research (AACR) meeting in New Orleans, USA from the 8th – 13th April 2022.

From Porvair Sciences Limited 7 Apr 2022

Newborn cells in patients with epilepsy, likely to provide a potential treatment

According to a study headed by researchers from USC Stem Cell and the USC Neurorestoration Center, adults may recover at least some of what they have lost by producing new brain cells, and this process is profoundly modified in patients with long-term epilepsy.

7 Apr 2022

Study sheds light on genetic causes of Alzheimer’s disease and other dementias

If we want to enhance our knowledge and treatment of Alzheimer’s disease, we need to identify genetic risk factors.

7 Apr 2022

Breakthrough discovery provides a desirable drug target to tackle metabolic diseases

In a breakthrough discovery, scientists from The University of Texas Health Science Center at San Antonio today reported that inhibiting a liver enzyme in obese mice decreased the rodents' appetite, increased energy expenditure in adipose (fat) tissues and resulted in weight loss.

6 Apr 2022

Gut microbiota may play a role in resistance to blood pressure medicines

Almost half of the U.S. adult population has high blood pressure - or hypertension - and about 20% of these patients have treatment-resistant hypertension.

6 Apr 2022

Researchers discover 15 genetic 'hotspots' that speed up or slow down brain aging

Researchers from a USC-led consortium have discovered 15 "hotspots" in the genome that either speed up brain aging or slow it down -; a finding that could provide new drug targets to resist Alzheimer's disease and other degenerative brain disorders, as well as developmental delays.

6 Apr 2022

A critical subset of supporting cells may lie at the origins of scleroderma

Supporting actors sometimes steal the show. In a new study published today in Cell, researchers headed by Prof. Ido Amit at the Weizmann Institute of Science have shown that supporting cells called fibroblasts, long viewed as uniform background players, are in fact extremely varied and vital.

5 Apr 2022

Checkpoint immunotherapy acts as an interface between killer T cells and dendritic cells

Chronic viral infections and cancers can damage the immune system permanently, diminishing the ability of immune killer T cells to destroy tumor cells or virus-infected cells—a condition known as “immune exhaustion.”

5 Apr 2022

Researchers discover new type of cell that may play a key role in human lung diseases

A new type of cell that resides deep within human lungs and may play a key role in human lung diseases has been discovered by researchers at the Perelman School of Medicine at the University of Pennsylvania.

4 Apr 2022

Plant compound may be a good therapeutic candidate for treating food allergies

Researchers combined advanced computational methods with experimental studies to gain new insight, at the cell level, into how the plant compound formononetin might be used to treat food allergies.

4 Apr 2022

Light-induced cellular apoptosis method can kill diseased cells without causing adverse reactions

Cancer has been the leading cause of death in Japan over the past 40 years. Despite the rise in patients due to the aging population, progresses in diagnosis and treatment are leading to higher survival rates.

1 Apr 2022

Research reveals how a building block protein assembles to form poxvirus scaffold

Researchers at the Okinawa Institute of Science and Technology Graduate University have revealed how poxviruses build their scaffold - a temporary protein coat that forms and disappears as the virus matures.

1 Apr 2022

Lifebit; Making Biomedical Data Accessible

In this interview, we speak to Dr. Maria Chatzou Dunford, CEO of Lifebit, about their technology and how it helps scientists to make better use of their data.

From Lifebit 1 Apr 2022

RNA targeted by small molecule drugs, likely to create new pathways for disease treatment

RNA (ribonucleic acid) is involved in many aspects of human health, and a new study published in the journal Nature provides compelling evidence that RNA could be a promising pharmacological target.

1 Apr 2022

Researchers show how proteins form DNA-repair mechanism in living bacteria

Two recent research have shown a completely new perspective of how bacterial cells repair broken parts of their DNA (lesions).

From New York University (NYU) 1 Apr 2022

ATM kinase inhibitor combines with target therapies to wipe out cancer cells

While cancer therapies that target specific genes or disease pathways might prolong life span, they can also result in highly resistant tumors when tiny reservoirs of cancer cells survive therapy, develop, and spread.

1 Apr 2022

Study helps to make sense of cell-to-cell variation in response to external stimuli

Why do genetically similar cells react to the same extrinsic stimuli, such as antibiotics, in such diverse ways?

1 Apr 2022

Exceptional research recordings display RNA switching “on” and “off”

RNA switches (also known as riboswitches) control which genes are turned “on” and “off”, much like a light switch. Although this appears to be a straightforward process, biologists have been astonished by the inner workings of these switches for decades.

1 Apr 2022

Drugs News and Research

Cryo-EM imaging of STING protein reveals a new binding source for immune attacks

Intracellular microbiota promote cell survival during tumor progression

Specialist assay kits and microplates for cancer research

Newborn cells in patients with epilepsy, likely to provide a potential treatment

Study sheds light on genetic causes of Alzheimer’s disease and other dementias

Breakthrough discovery provides a desirable drug target to tackle metabolic diseases

Gut microbiota may play a role in resistance to blood pressure medicines

Researchers discover 15 genetic 'hotspots' that speed up or slow down brain aging

A critical subset of supporting cells may lie at the origins of scleroderma

Checkpoint immunotherapy acts as an interface between killer T cells and dendritic cells

Researchers discover new type of cell that may play a key role in human lung diseases

Plant compound may be a good therapeutic candidate for treating food allergies

Light-induced cellular apoptosis method can kill diseased cells without causing adverse reactions

Research reveals how a building block protein assembles to form poxvirus scaffold

Lifebit; Making Biomedical Data Accessible

RNA targeted by small molecule drugs, likely to create new pathways for disease treatment

Researchers show how proteins form DNA-repair mechanism in living bacteria

ATM kinase inhibitor combines with target therapies to wipe out cancer cells

Study helps to make sense of cell-to-cell variation in response to external stimuli

Exceptional research recordings display RNA switching “on” and “off”

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