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Revealing the functional significance of DDX41 in great detail

The DDX41 gene encodes the nuclear enzyme DEAD-box-type RNA helicase. Hematopoietic malignancies are caused by DDX41 mutations. However, the mechanism behind the development of this malignancy remains unknown.

21 Nov 2022

Applying “programmable molecular scissors” to combat COVID-19 infection

As an approach that could be used to create a new class of antiviral drugs, synthetic biology was used by Cambridge scientists to artificially create enzymes programmed to attack the genetic code of SARS-CoV-2 and eliminate the virus.

17 Nov 2022

Researchers create genetic 'devices' to perform computations like artificial neural circuits

Bringing together concepts from electrical engineering and bioengineering tools, Technion and MIT scientists collaborated to produce cells engineered to compute sophisticated functions – "biocomputers" of sorts.

15 Nov 2022

NIH funds research on mRNA vaccines to stop cancer development

The National Cancer Institute at the National Institutes of Health has awarded a multidisciplinary team of Weill Cornell Medicine researchers a five-year $5.7 million grant to support a center dedicated to creating messenger RNA (mRNA) vaccines to prevent the development of cancer in at-risk groups.

15 Nov 2022

Genetically modifying plant protein to yield more vegetable oil

At the Nanyang Technological University, Singapore (NTU Singapore), researchers have been successful in genetically modifying a plant protein that is accountable for oil accumulation in edible nuts and plant seeds.

From Nanyang Technological University Singapore (NTU Singapore) 11 Nov 2022

Recognizing how the HIV-1 evades immune system

According to a recent study led by Andrés Finzi, a professor at the Université de Montréal and researcher at the CHUM Research Centre, the type of virus used as a model to study the effectiveness of non-neutralizing antibodies against the virus that causes AIDS, has a crucial role to play.

10 Nov 2022

DNA barcoding tracks the progression of tumor cells through time

According to a recent study from the Garvan Institute of Medical Research, some cancer cells can use parallel mechanisms to elude immune system defenses and withstand immunotherapy treatment.

8 Nov 2022

Testing for residual solvents and terpenes in cannabis

AZoLifeSciences sat down with Tom Kwoka, Senior Application Scientist - GC/MS at PerkinElmer, and Alex Maitain, GC/MS Cannabis Analysis at PerkinElmer, to discuss the benefits of analyzing residual solvents and terpenes from cannabis and hemp products by Headspace GC/MS analysis.

From PerkinElmer 8 Nov 2022

Research sheds light into how a person's daily rhythm and activity levels relate to intelligence

Night owls may be looking forward to falling back into autumn standard time but a new study from the University of Ottawa has found Daylight Saving Time may also suit morning types just fine.

7 Nov 2022

High-throughput quantitative phase microscopy yields promising results

Numerous cellular life processes include the organelles of cells. Their malfunction and the growth and spread of cancer are strongly connected.

4 Nov 2022

Different cancers carry distinctive genetic signatures

After analyzing data from a public repository, CD4-T, CD8-T cells, and Treg cells, a team of researchers led by bioinformatics Mabel Vidal from the University of Concepcion and working with researchers from MELISA Institute and other academic institutions discovered a distinctive genetic signature among subsets of infiltrating T cells of various types of cancer.

4 Nov 2022

Role of p53-mediated metabolism in preventing genomic instability

The gene that codes for the protein p53 is most likely the most significant factor in defending human cells against DNA-damaging agents that cause cancer. The protein permits cells to repair DNA damage and so prevents the formation of malignancies, earning it the nickname “guardian of the genome.”

4 Nov 2022

UJ scientists find a faster way to screen soil bacteria as potential biologicals

Researchers found a much faster way to screen soil bacteria as potential biostimulants and bio-pesticides.

2 Nov 2022

Genetic timestamping tracks the fate of plasma cells over time

Vaccines function by effectively producing immune cells that live for a long time, frequently for decades. These immune cells form a protective barrier that prevents or reduces re-infection, as well as a memory that enables one to identify an old invader, such as a virus, and eliminate it before it causes disease.

1 Nov 2022

New tool advances potential means to deliver gene therapy

Researchers from Johns Hopkins Medicine claim to have successfully “slid” genetic instructions into a cell and produced essential proteins that were lacking from those cells using a cell’s normal process for creating proteins.

1 Nov 2022

Resistance against Epstein-Barr virus from experimental monoclonal antibodies

When tested in a lab setting using human cells, a panel of experimental monoclonal antibodies (mAbs) that target various Epstein-Barr virus (EBV) sites prevented infection.

1 Nov 2022

Identifying the structure of the SEA complex

The mTOR protein is important for cell growth, proliferation, and survival. Its activity fluctuates according to nutrient availability and growth factors like hormones.

1 Nov 2022

Novel method tags proteins from specific cancer cells

Biomarkers are extremely useful tools that enable doctors to research biology and disease by, for instance, diagnosing a disease from a blood or tissue sample, predicting whether a treatment will be beneficial in a person, or determining how much of a drug is entering diseased cells.

28 Oct 2022

Sphere Fluidics opens new laboratory facilities at Granta Park in Cambridgeshire, UK

Sphere Fluidics, a company developing single cell analysis systems underpinned by its patented picodroplet technology, announced today that it has opened a new state-of-the-art facility in Granta Park, Cambridgeshire, UK, to support the Company’s growth.

From Sphere Fluidics Limited 25 Oct 2022

Bacteria do engage in photosynthesis, research suggests

Knowing whether or not marine microbes engage in photosynthesis -; the use of sunlight to turn carbon dioxide and water into energy -; could help scientists to learn if ocean bacteria play a role in the global carbon cycle.

25 Oct 2022