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New protein design could help in drug discovery for Parkinson’s disease

The neurotransmitter dopamine plays a vital role in everything, starting from motor control to higher cognitive functions, arousal, motivation, sexual gratification, and reinforcement.

12 Jun 2020

Researchers develop intracellular biopsy to isolate targeted miRNAs from living cells

MicroRNAs, are attracting interest relating to human diseases because variations in the expression of miRNAs are often associated with abnormal functions.

11 Jun 2020

Interaction between neurons and glial cells boosts appetite

Tanycytes are essentially glial cells, which interact with neurons in the brain to inform this organ about the type of food consumed by individuals.

From The University of Warwick 9 Jun 2020

Automated 3D brain imaging data analysis helps unravel complex neural circuits

Automated 3-D brain imaging data analysis technology offers more reliable and standardized analysis of the spatial organization of complex neural circuits.

9 Jun 2020

Single-cell-resolution technologies help map brain regions in humans and primates

Using the single-cell-resolution transcriptomics technologies, researchers have performed a large-scale analysis of gene expression in 33 different brain regions of chimpanzees, bonobos, macaques, and humans, and successfully generated a map of the various brain regions with their particular cell structures.

5 Jun 2020

Study uncovers why developing nerve cells take a wrong turn

A group of scientists from CECAD, the Cluster of Excellence 'Cellular Stress Responses in Aging-Associated Diseases,' have found a mechanism by which neurodevelopmental diseases concerning neurons can be explained: The loss of a certain enzyme, UBE2K, impeded the differentiation of stem cells by silencing the expression of genes important for neuronal differentiation and, therefore, the development and generation of neurons.

4 Jun 2020

Stem cell model sheds new light on neurodegeneration process

A new study published today in Neuron led by The New York Stem Cell Foundation Research Institute's Valentina Fossati, Ph.D., creates astrocytes - an integral support cell in the brain - from stem cells and shows that in disease-like environments, these normally helpful cells can turn into neuron-killers.

2 Jun 2020

Gut-brain connection may help treat neurological diseases

Researchers are not clear whether mucus is the first line of defense against bad bacteria in the human gut.

2 Jun 2020

Toxic tau may spread in the brain via connected neurons

Toxic versions of the protein tau are believed to cause the death of neurons of the brain in Alzheimer's disease.

1 Jun 2020

Research identifies how neuronal transmission is disrupted in ALS

Patients with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, lose muscle control as nerve cells or neurons in the brain and spinal cord degenerate and can no longer send signals to muscles.

29 May 2020

Study highlights crucial role of immune-system molecule in Huntington's disease

More than a decade before people with Huntington's disease show symptoms, they can exhibit abnormally high levels of an immune-system molecule called interleukin-6 (IL-6), which has led many researchers to suspect IL-6 of promoting the eventual neurological devastation associated with the genetic condition.

28 May 2020

Making opioids safer and more effective

Dr. John Streicher speaks to AZoLifeSciences about his research on improving opioid drugs to make them safer and more effective.

From University of Arizona 28 May 2020

Fruit fly study helps explain why it is so hard to wake up on a winter morning

Winter may be behind us, but do you remember the challenge of waking up on those cold, dark days? Temperature affects the behavior of nearly all living creatures, but there is still much to learn about the link between sensory neurons and neurons controlling the sleep-wake cycle.

26 May 2020

Gene associated with thinness may play a role in resisting weight gain

Some people can remain slim easily, irrespective of their diet, while others might be dieting and working out at the gym to maintain their shape.

25 May 2020

Innovative two-photon microscopy enables in vivo subcellular imaging of the retina

Retina is the only part of the central nervous system that can be visualized noninvasively with optical imaging approaches.

21 May 2020

Aging neurons build up DNA damage, study finds

MIT neuroscientists have discovered that an enzyme called HDAC1 is critical for repairing age-related DNA damage to genes involved in memory and other cognitive functions.

18 May 2020

Researchers discover group of genes with altered expression in autism

Autism has long been associated only with behavioral and environmental factors, but the role of genetics in its development is now increasingly evident. Some 100 genes have been found to play a role in autism spectrum disorder, and another thousand are being studied to the same end.

15 May 2020