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Integrating Ultrasound with Genetics to Precisely Modify Neurons in the Brain

Researchers have developed methods to study and manipulate areas of the brain, though many of those methods are restricted by the limited depth that light can reach within the brain. A multidisciplinary team at Washington University in St. Louis plans to overcome that limitation by integrating ultrasound with genetics to precisely modify neurons in the brain.

28 Jul 2023

Analyzing DNA Damage-Induced NF-κB Targeted by Novel Small Molecule Inhibitors

Chemotherapy and radiotherapy aim to destroy cancer cells by inducing DNA double-strand breaks – damage that, once inflicted, usually causes the cells to die. But damage to a cell's genetic material also activates a signaling pathway called IKK/NF-κB that helps prevent cell death, thus limiting the success of these treatments in patients.

28 Jul 2023

New Proof-of-Concept Model for Delivering Gene Editing Tools to Treat Blood Disorders

In a step forward in the development of genetic medicines, researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have developed a proof-of-concept model for delivering gene editing tools to treat blood disorders, allowing for the modification of diseased blood cells directly within the body.

28 Jul 2023

New Method Facilitates Early Detection and Localization of Tumors

To help with early tumor diagnosis and tumor localization, researchers have devised a technology that concurrently detects many cancer-specific DNA circulating hallmarks.

26 Jul 2023

Scientists Discover Secret of Virgin Birth, and Switch on the Ability in Female Flies

Scientists have pinpointed a genetic cause for virgin birth for the first time, and once switched on the ability is passed down through generations of females.

26 Jul 2023

Caecilians Pass Microbes to Their Young Through Skin-Feeding

Caecilians are an elusive type of amphibian that primarily live underground and look like a cross between a worm and a snake. One of the few things that is known about caecilians is their unique method for feeding their young.

25 Jul 2023

Atomic-Level Analysis of Synthetic DNA to Reveal New Treatment Options

West Virginia University researchers can now see synthetic DNA at the atomic level, allowing them to learn how to tweak its structure to improve its scissor-like function.

25 Jul 2023

New Process by Which Enzymes Help Prevent Heart Damage in Chemotherapy Patients Identified

Researchers at the University of Illinois Chicago have identified a process by which enzymes can help prevent heart damage in chemotherapy patients.

21 Jul 2023

Researchers Pinpoint the Genes that Shape the Skeletons

Using artificial intelligence to analyze tens of thousands of X-ray images and genetic sequences, researchers from The University of Texas at Austin and New York Genome Center have been able to pinpoint the genes that shape our skeletons, from the width of our shoulders to the length of our legs.

21 Jul 2023

Study Identifies a Gene That Largely Controls Weeping Growth in Apple

Plant geneticists have identified a mutation in a gene that causes the "weeping" architecture – branches growing downwards – in apple trees, a finding that could improve orchard fruit production.

21 Jul 2023

Analyzing Microbe-Induced Drought Tolerance by ABA-Mediated Root Architecture

Priming crop plants with a microbe sourced from the roots of desert plants could be a powerful tool to boost crop plant's resilience to drought.

21 Jul 2023

Researchers Make Breakthrough in Fight Against Familial Hypercholesterolemia

The Mona Lisa, painted by the Italian artist Leonardo da Vinci, is one of the most recognizable paintings in the world.

21 Jul 2023

Engineering Plants for Resilience to Climate Change

Climate change is affecting the types of plant varieties we can cultivate, as well as how and where we can do so. A new collection of articles in the open access journal PLOS Biology explores the twin challenges of engineering plants for resilience to climate change and enhancing their carbon-capture potential.

20 Jul 2023

T-Cell Analysis for Type 1 Diabetes Preventive Therapy

Scripps Researchers have found that looking at a certain type of immune cell in the blood can help pinpoint those who are most vulnerable to acquiring type 1 diabetes, a fatal autoimmune disease

20 Jul 2023

New Vaccine Shows Promise in Combating MenB

Investigators from the Universities of Surrey and Oxford have declared that a vaccine candidate that can shield children from Meningococcal group B (MenB), which can cause meningitis, has advanced to clinical development.

19 Jul 2023

New Study Highlights Genetic Variations for a Precision Medicine Approach

There are genetic variations among children with a rare neurodevelopmental disease, according to a new study headed by the Seaver Autism Center for Study and Treatment at Mount Sinai. This discovery could set the path for a precision medicine approach to treating these children.

18 Jul 2023

Genomic Insights Into the Diversification of Clownfish

Clownfish, renowned for their vibrant colors and unusual symbiotic relationship with sea anemones, have long captivated the imagination of scientists and nature enthusiasts alike.

18 Jul 2023

Scientists Discover Specific Genes Involved in Rare, Life-Threatening Heart Disease

By identifying genes in patients and testing their effects in fruit flies, researchers from Sanford Burnham Prebys have found new genes that contribute to hypoplastic left heart syndrome (HLHS), a rare, life-threatening heart disease that occurs in infants.

18 Jul 2023

5-ALA Opens New Avenues for Treating Mitochondrial Disorders

At the Tokyo Metropolitan University, researchers have shown that 5-aminolevulinic acid (5-ALA) aids bypass deficiencies in Complex I (CI), the first in a series of protein complexes that transport electrons and assist in powering the mitochondria.

17 Jul 2023