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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

UC Riverside scientists aim to turn edible plants into mRNA vaccine factories

The future of vaccines may look more like eating a salad than getting a shot in the arm. UC Riverside scientists are studying whether they can turn edible plants like lettuce into mRNA vaccine factories.

17 Sep 2021

Researchers capture the assembly of ribosomes within human cells

Ribosomes are the multi-component molecular machines that create complex proteins by binding building blocks together as per instructions encoded in the messenger RNAs of the cell.

16 Sep 2021

Researchers infer chemical steps involved in methylthiolation of tRNAs

Recent research revealed the chemical steps in a vital cellular modification mechanism that inserts a chemical tag to certain RNAs. Interference of this process in humans can result in cancers, diabetes, and neuronal diseases.

From Penn State University 16 Sep 2021

Researchers develop novel cell reprogramming strategy to slow down glioblastomas

Gliomas are the most common primary brain tumors in adults. Among them, high-grade glioblastomas (GBMs) are particularly known to be notoriously aggressive and invasive, which makes it challenging to treat them.

16 Sep 2021

UTHSC researcher receives grant to extend work on The Cancer Genome Atlas project

Neil Hayes, MD, MPH, director of the Center for Cancer Research at the University of Tennessee Health Science Center, is one of two principal investigators for a $1.8 million grant that extends the work of The Cancer Genome Atlas (TCGA), a groundbreaking multisite project to understand cancer at its molecular level through genome sequencing and extensive data analysis.

16 Sep 2021

Aptamers for Targeting SARS-CoV-2 Proteins

AMSBIO has further expanded its product range to help in the fight against COVID-19 with the introduction of a new range of aptamers targeting SARS-CoV-2 proteins to aid development of new kits and assays.

From AMS Biotechnology 15 Sep 2021

Newly discovered RNA-guided endonucleases can be harnessed for genome editing in cells

Researchers seeking to understand the origins of CRISPR-Cas9 systems have uncovered a class of transposon-encoded RNA-guided nucleases, which they dubbed "OMEGA," that could be harnessed for genome editing in human cells.

14 Sep 2021

Study uncovers mechanism where two transcription factors stabilize each other’s binding to DNA

Researchers have discovered an exclusive mechanism through which two transcription factors stabilize each other’s binding to DNA in fission yeast.

14 Sep 2021

Study could help choose the ideal DNA extraction method for microbiome research

Let's face it, we are a results-driven society. Too focused on the outcome, people don't often think about the "how." For instance, did you think about "how" you got to work this morning or did you just get there? In microbiome studies the results are the graphs and the data but the "how," like commuting, is often just part of a routine.

13 Sep 2021

Viruses buried in marsupials' DNA may help protect against future infections

Fossils of ancient viruses are preserved in the genomes of all animals, including humans, and have long been regarded as junk DNA. But are they truly junk, or do they actually serve a useful purpose?

From The University of New South Wales (UNSW) 9 Sep 2021

Study unearths previously unknown role of CTCF, the transcription regulator

Researchers discovered evidence that CTCF governs chromatin accessibility, the mechanism of opening tightly spooled DNA facilitating gene expression.

9 Sep 2021

Study explores the efficiency of CasMINI, an engineered CRISPR-Cas system

A compact CRISPR-Cas system, known as CasMINI, can be employed for gene-therapy and cell-engineering applications as it is easier to deliver into cells.

7 Sep 2021

Study suggests a simple mechanism could underlie the self-replication of protocells

Recent research suggests that a simple process could underlie the growth and self-replication of protocells—putative ancestors of modern living cells.

7 Sep 2021

Researchers engineer CAR T cells to enhance their function

Chimeric antigen receptor (CAR) T cell therapy employs engineered T cells to treat certain kinds of cancers.

7 Sep 2021

Researchers discover the role of a retrotransposon in horizontal memory transfer in roundworms

When an organism encounters a threat in its environment, it is to the species' advantage to warn others of the peril.

6 Sep 2021

Miniature CRISPR-Cas system expands applicability and implications further

For the first time, Stanford researchers have miniaturized CRISPR for mammalian gene editing, which magnifies the scope of CRISPR technology.

3 Sep 2021

Experts decode the genetic mechanism governing the speed of mRNA translation

The genetic material of all eukaryotic organisms is stored in the cell nucleus in the form of DNA. The DNA is first transcribed into messenger RNA in the cell cytoplasm and later translated into protein using ribosomes for it to be used, where ribosomes are small machines capable of decoding messenger RNA to synthesize the relevant proteins.

1 Sep 2021

Researchers identify new forms of mosquito immune cells

Recent research detailing mosquito immune cells provides insights into the insect immune system and how mosquitoes transmit parasites that result in malaria.

31 Aug 2021

Stanford researchers use machine learning approach to solve structural biology challenges

Determining the 3D shapes of biological molecules is one of the hardest problems in modern biology and medical discovery. Companies and research institutions often spend millions of dollars to determine a molecular structure – and even such massive efforts are frequently unsuccessful.

27 Aug 2021

Researchers develop a method to engineer new functionalities into cells

Researchers at the Institute of Molecular Biology and Johannes Gutenberg University Mainz have developed a method to engineer new functionalities into cells. The results were published today in the journal Cell in the article "Dual film-like organelles enable spatial separation of orthogonal eukaryotic translation".

26 Aug 2021

RNA News and Research

UC Riverside scientists aim to turn edible plants into mRNA vaccine factories

Researchers capture the assembly of ribosomes within human cells

Researchers infer chemical steps involved in methylthiolation of tRNAs

Researchers develop novel cell reprogramming strategy to slow down glioblastomas

UTHSC researcher receives grant to extend work on The Cancer Genome Atlas project

Aptamers for Targeting SARS-CoV-2 Proteins

Newly discovered RNA-guided endonucleases can be harnessed for genome editing in cells

Study uncovers mechanism where two transcription factors stabilize each other’s binding to DNA

Study could help choose the ideal DNA extraction method for microbiome research

Viruses buried in marsupials' DNA may help protect against future infections

Study unearths previously unknown role of CTCF, the transcription regulator

Study explores the efficiency of CasMINI, an engineered CRISPR-Cas system

Study suggests a simple mechanism could underlie the self-replication of protocells

Researchers engineer CAR T cells to enhance their function

Researchers discover the role of a retrotransposon in horizontal memory transfer in roundworms

Miniature CRISPR-Cas system expands applicability and implications further

Experts decode the genetic mechanism governing the speed of mRNA translation

Researchers identify new forms of mosquito immune cells

Stanford researchers use machine learning approach to solve structural biology challenges

Researchers develop a method to engineer new functionalities into cells

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