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Researchers use super-resolution microscopy to study close protein associations

With the advent of super-resolution microscopy, scientists can study close protein associations better than ever before.

10 Jul 2020

Single-nucleus RNA sequencing helps compare transcriptional responses to acute cocaine

The lab of Jeremy Day, Ph.D., at the University of Alabama at Birmingham, has used single-nucleus RNA sequencing approaches to compare transcriptional responses to acute cocaine in 16 unique cell populations from a portion of the brain called the nucleus accumbens, or NAc.

From University of Alabama 10 Jul 2020

Study explains why human mitochondrial genomes mutate frequently

One could say that mitochondria, the energy-producing organelles inside every human cell, dance to their own beat.

10 Jul 2020

TMEM106B gene reveals the causes of neurodegenerative diseases

Across the globe, approximately 50 million people are living with dementia. The two most common forms are Alzheimer's disease and frontotemporal lobar degeneration (FTLD), which develop when neurons in specific parts of the brain stop functioning - triggering memory loss and other behavioral or personality changes.

10 Jul 2020

Metabolomics can help understand the impact of calorie-restricted diets on aging

Changes in a few small molecules involved in a cell's metabolism seem to indicate whether a restricted "life extension" diet will actually extend, shorten, or have no effect on lifespan, a study of fruit flies has found.

10 Jul 2020

Study: Deep-sea microbes could have large amounts of available energy

Microbial cells are found in abundance in marine sediments beneath the ocean and make up a significant amount of the total microbial biomass on the planet.

10 Jul 2020

Bioinformaticians reveal previously unknown features of genes involved in brain functioning

In a recent study of genes involved in brain functioning, their previously unknown features have been uncovered by bioinformaticians from the Moscow Institute of Physics and Technology and the Institute of Mathematical Problems of Biology, RAS. The findings are reported in PLOS One.

10 Jul 2020

High concentrations of blood sodium can influence the biological clock of mice

A new study from McGill University shows that increases in the concentrations of blood sodium can have an influence on the biological clock of mice, opening new research avenues for potentially treating the negative effects associated with long-distance travel or shift work.

10 Jul 2020

Expansion stress promotes immunosuppression and enhances growth of breast cancer cells

Expansion stress can have an alarming impact on breast cancer cells by creating conditions that could lead to dangerous acceleration of the disease, an interdisciplinary team of University of Alabama at Birmingham researchers has found.

10 Jul 2020

Salmonella biofilm protein can cause autoimmunity and arthritis in animals

Scientists from the Vaccine and Infectious Disease Organization-International Vaccine Centre at the University of Saskatchewan and Temple University have demonstrated that a Salmonella biofilm protein can cause autoimmune responses and arthritis in animals.

10 Jul 2020

CU scientists identify key role of brain's immune cells during development

Researchers at the University of Colorado School of Medicine have identified how specific brain cells interacting during development could be related to neurological and neuropsychiatric diseases, including some that occur later in life.

10 Jul 2020

Preventing immune cell reprogramming could be a new way to stop breast cancer metastasis

Natural killer cells, a type of immune cell, are known to limit metastasis by inducing the death of cancer cells. But metastases still form in patients, so there must be ways for cancer cells to escape.

10 Jul 2020

ASC-enriched fat grafts for breast augmentation could produce superior results

Results of a clinical trial released today in STEM CELLS Translational Medicine indicates that breast augmentation in patients treated with fat grafts enriched with autologous adipose-derived stem cells (ASCs) had significantly superior results compared to those treated with non-enriched grafts.

9 Jul 2020

Supergenes may have a massive role in evolutionary adaption

Massive blocks of genes--inherited together 'plug and play' style--may play a larger role in evolutionary adaption than previously thought, according to new research in Nature.

9 Jul 2020

Research uncovers how 'reubiquitination' promotes elimination of misfolded membrane proteins

Chinese researchers recently discovered a protein quality control mechanism called "reubiquitination".

9 Jul 2020

New type of molecular editor can make precise changes in mitochondrial DNA

The genome in mitochondria -- the cell's energy-producing organelles -- is involved in disease and key biological functions, and the ability to precisely alter this DNA would allow scientists to learn more about the effects of these genes and mutations.

9 Jul 2020

Report highlights role of genomics in perpetuating racism and inequality

Genomics is crowding out ways of reducing inequality, has thwarted medicine from advancing justice, and is creating new forms of social classification and surveillance.

9 Jul 2020

Researchers discover how good gut bacteria can help reduce heart disease risk

Scientists have discovered that one of the good bacteria found in the human gut has a benefit that has remained unrecognized until now: the potential to reduce the risk for heart disease.

9 Jul 2020

New spatial mapping method pinpoints new potential therapeutic targets for lupus

A team of researchers from Children's Hospital of Philadelphia used a new method of pinpointing potential disease-causing changes in the genome to identify two new potential therapeutic targets for lupus, while also paving the way for more accurately identifying disease-causing variations in other autoimmune disorders.

9 Jul 2020

Super-resolution microscopy methods reveal the smallest cell structures

Theoretically, high-resolution microscopy should make it possible to capture cell structures that have a resolution of a few nanometers.

8 Jul 2020

Research News and Research

Researchers use super-resolution microscopy to study close protein associations

Single-nucleus RNA sequencing helps compare transcriptional responses to acute cocaine

Study explains why human mitochondrial genomes mutate frequently

TMEM106B gene reveals the causes of neurodegenerative diseases

Metabolomics can help understand the impact of calorie-restricted diets on aging

Study: Deep-sea microbes could have large amounts of available energy

Bioinformaticians reveal previously unknown features of genes involved in brain functioning

High concentrations of blood sodium can influence the biological clock of mice

Expansion stress promotes immunosuppression and enhances growth of breast cancer cells

Salmonella biofilm protein can cause autoimmunity and arthritis in animals

CU scientists identify key role of brain's immune cells during development

Preventing immune cell reprogramming could be a new way to stop breast cancer metastasis

ASC-enriched fat grafts for breast augmentation could produce superior results

Supergenes may have a massive role in evolutionary adaption

Research uncovers how 'reubiquitination' promotes elimination of misfolded membrane proteins

New type of molecular editor can make precise changes in mitochondrial DNA

Report highlights role of genomics in perpetuating racism and inequality

Researchers discover how good gut bacteria can help reduce heart disease risk

New spatial mapping method pinpoints new potential therapeutic targets for lupus

Super-resolution microscopy methods reveal the smallest cell structures

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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