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New approach spurs production of antibiotic or antiparasitic compounds in bacteria

Researchers have developed a method to spur the production of new antibiotic or antiparasitic compounds hiding in the genomes of actinobacteria, which are the source of drugs such as actinomycin and streptomycin and are known to harbor other untapped chemical riches.

26 Jun 2020

Simplified artificial cell sheds light on the dynamics of cellular symmetry

Symmetry and asymmetry are fundamental properties of nature. Seen from above, butterflies have left-right symmetry, while male fiddler crabs show dramatic asymmetry.

26 Jun 2020

Angpt2 hormone can help treat obesity-induced metabolic disorders

Obesity is usually categorized into metabolically healthy obesity (MHO) and also into an unhealthy version of obesity.

26 Jun 2020

C. difficile hijacks the wound healing system to cause serious and persistent disease

Monash University researchers have discovered that the devastating bacterial superbug Clostridioides difficile hijacks the human wound healing system in order to cause serious and persistent disease, opening up the development of new therapies to treat the disease.

26 Jun 2020

New imaging techniques reveal individual transcription factor proteins in real time

A new study provides a new understanding of the mechanisms through which DNA-binding proteins look for the genome for their particular binding sites.

26 Jun 2020

Scientists pinpoint mutations that makes bacteria deadlier

As far as humans are concerned, bacteria can be classified as either harmful, pathogenic bacteria and harmless or beneficial non-pathogenic bacteria.

26 Jun 2020

Lesion segregation can drive complex patterns of mutations in tumor genomes

Researchers from the German Cancer Research Center, Cambridge, and Edinburgh have been analyzing the evolution of tumors after chemical damage.

26 Jun 2020

Investing in the fight against climate change in the wake of COVID-19

Françoise d’Estais of the UN discusses the Global Trends in Renewable Energy Investment 2019 and the need to invest in renewables in the COVID-19 recovery.

From United Nations 26 Jun 2020

Feed additive shows promise to mitigate enteric methane emissions in dairy cows

The enteric methane mitigation potential of 3-nitrooxypropanol (3-NOP) has been confirmed in previous studies. 3-NOP is highly soluble and rapidly metabolized in the rumen.

25 Jun 2020

Study identifies complex functional, physical interactions between p53 gene and the INSR pathway

Volume 11, Issue 25 of @Oncotarget reported that the present study was aimed at evaluating the hypothesis that p53 governs the expression and activation of the INSR gene in breast cancer cells.

25 Jun 2020

A metabolic enzyme could be a potential drug target for B cell lymphomas

Scientists at the Sloan Kettering Institute have found that increased activity of a normal metabolic enzyme can lead to cancer.

25 Jun 2020

Researchers discover new druggable pathway linked with tuberous sclerosis

Tuberous sclerosis complex (TSC) is a neurological disorder causing non-cancerous tumors, called cortical tubers, to grow throughout the brain and body, as well as other conditions like epilepsy and autism.

25 Jun 2020

Whole genome sequencing can improve rare disease diagnosis

A research programme pioneering the use of whole genome sequencing in the NHS has diagnosed hundreds of patients and discovered new genetic causes of disease.

25 Jun 2020

Subtypes in alzheimer's disease may be linked to tau protein modifications

A new study reveals a possible biological reason that Alzheimer's Disease (AD) progresses at different rates in different patients.

25 Jun 2020

Turning biomass DNA into degradable materials

DNA has a lot of handy uses. It stores the blueprint of genetic code. It helps usher along the evolution of species.

25 Jun 2020

Efficient laser technique can convert cellulose into biofuel

With the imminent threat of a climate crisis hanging over our heads, it has become crucial to develop efficient alternatives to fossil fuels.

25 Jun 2020

Carbon Cycling In Wet Soils

Under changing, temperate soils are forecast to experience a high degree of variability in moisture conditions due to periods of drought and/or flood.

25 Jun 2020

Study shows how chemicals cause complex cell mutations

Fresh insights into why some harmful substances are so efficient at causing cancer could aid the quest for better treatments.

25 Jun 2020

Blocking A 'Jamming Signal' Can Unleash Immune System To Fight Tumors

Yale researchers have discovered a "jamming signal" that blocks a powerful immune system stimulant called interleukin-18 (IL-18) from reaching tumors.

25 Jun 2020