Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Enhancing outcomes after surgery of breast cancer patients with miR-145

According to research results published online ahead of print in the Journal of the American College of Surgeons (JACS), microRNA (miRNA) can be used as a biomarker to identify which individuals are most likely to experience breast cancer recurrence and mortality.

8 Nov 2022

UJ scientists find a faster way to screen soil bacteria as potential biologicals

Researchers found a much faster way to screen soil bacteria as potential biostimulants and bio-pesticides.

2 Nov 2022

All normal human tissues express remnants of widespread retrovirus

Ancient viral remnants in the human genome are active in both healthy and diseased tissues, restricting their applicability as disease indicators, according to a study published on October 18th, 2022, in the open access journal PLOS Biology by Aidan Burn at Tufts University in Boston, USA and colleagues.

20 Oct 2022

Microbes in the human gut impact neurological and emotional health

According to a recent viewpoint piece in Science by a UT Southwestern researcher, there is growing evidence that the microbes found in the human stomach might also affect a person’s neurological and emotional health.

9 Sep 2022

SLFN11’s surveillance part in protein homeostasis

On July 25th, 2022, a new study perspective called “SLFN11’s surveillance role in protein homeostasis” was published in Volume 9 of Oncoscience.

8 Aug 2022

Researchers identify the molecular route that leads to autoimmune disease inflammation

Mitochondria are self-contained organelles that reside inside cells and are tasked with producing the chemical energy required to power vital tasks necessary for life and wellbeing. They have their own mini-chromosome and DNA.

From UC San Diego 14 Jul 2022

Study shows how mitochondrial RNA changes enhance invasive growth of cancer cells

The energy centers of cells and mitochondria have their own genetic material and RNA molecules.

1 Jul 2022

Discovery may reveal new ways to control plant growth

Understanding how plants process light is key to improving crop yields. Light helps plants know when to grow and flower at the right time.

15 Jun 2022

Computational approach could enable large-scale analyses of tumor-specific total mRNA levels from patient samples

Researchers at The University of Texas MD Anderson Cancer Center have developed a new approach to quantify tumor-specific total mRNA levels from patient tumor samples, which contain both cancer and non-cancer cells.

14 Jun 2022

Computational DNA droplet recognizes a specific combination of tumor biomarker microRNAs

The formation of aqueous droplets in macromolecules by liquid-liquid phase separation (or coacervation) is a popular topic in life sciences research. DNA is particularly interesting among the numerous macromolecules that form droplets because it is predictable and programmable, both of which are desirable properties in nanotechnology.

6 Jun 2022

Researchers conduct a comprehensive survey of the aging epigenome across the chromatin hierarchy

Highly structured chromatin encodes the program of life with only one set of genes in the core of every cell. Since various genes are stimulated at different periods of life while staying silent elsewhere, this is feasible. Some genes from a former life stage are hidden deep within the nuclear perimeter, while others manage to break out.

1 Jun 2022

Researchers devise a new treatment approach to cure aggressive brain tumors

Glioblastomas (GBMs) are cancerous tumors of the brain and spinal cord that are incredibly aggressive.

23 May 2022

Cancer biomarkers relying on methylation could forecast tumor type

In cancer management, biomarkers are commonly used to guide treatment decisions and evaluate patient outcomes.

23 May 2022

Study underscores the crucial role of genomic profiling in diagnosing and grading brain tumors

Patients diagnosed with a type of brain tumor survived for longer when they were treated aggressively with surgery, radiation and chemotherapy.

22 Apr 2022

Research reveals how RNA elements control cleavage activity of DICER enzyme in pre-miRNA and shRNAs

A research team led by scientists from the Hong Kong University of Science and Technology has revealed how secondary structure RNA elements control the cleavage activity of the DICER enzyme in both pre-miRNA and short-hairpin RNAs, improving the understanding of the DICER cleavage mechanism and providing a foundation for the design of accurate and efficient short-hairpin RNAs for gene-silencing.

20 Apr 2022

Biomarker News and Research

Enhancing outcomes after surgery of breast cancer patients with miR-145

UJ scientists find a faster way to screen soil bacteria as potential biologicals

All normal human tissues express remnants of widespread retrovirus

Microbes in the human gut impact neurological and emotional health

SLFN11’s surveillance part in protein homeostasis

Researchers identify the molecular route that leads to autoimmune disease inflammation

Study shows how mitochondrial RNA changes enhance invasive growth of cancer cells

Discovery may reveal new ways to control plant growth

Computational approach could enable large-scale analyses of tumor-specific total mRNA levels from patient samples

Computational DNA droplet recognizes a specific combination of tumor biomarker microRNAs

Researchers conduct a comprehensive survey of the aging epigenome across the chromatin hierarchy

Researchers devise a new treatment approach to cure aggressive brain tumors

Cancer biomarkers relying on methylation could forecast tumor type

Study underscores the crucial role of genomic profiling in diagnosing and grading brain tumors

Research reveals how RNA elements control cleavage activity of DICER enzyme in pre-miRNA and shRNAs

Spatial maps offer insights into the battle between melanoma cells and immune cells

Biologists unravel the mystery behind nuclear anomaly in blood cancer cells

Proteins in saliva could serve as a biomarker to identify patients at risk for severe COVID-19

Researchers identify new set of protein biomarkers for cancer using breast milk

Researchers discover abnormal gene mutations that lead to cancer development

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