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Novel Approach to Predict and Optimize CAR-T Cell Therapy

A significant turning point in the battle against cancer has been the recent development of CAR-T technology.

30 Oct 2024

Study Links Archaic Gene Variant to Health Risks in First Nations Oceanians

An ancient gene mutation among First Nations inhabitants of Oceania may make them more susceptible to infectious diseases like influenza, according to a new study by scientists at the University of Colorado Anschutz Medical Campus.

30 Oct 2024

Study Reveals How Cells Rearrange Cytoskeletal Structures During Division

A living cell is a bustling metropolis, with countless molecules and proteins navigating crowded spaces in every direction.

30 Oct 2024

Encrypted Peptides Offer Hope Against Antibiotic-Resistant Infections

Researchers have discovered a new class of antimicrobial compounds called encrypted peptides, which could boost the immune system's toolkit to combat infection and counteract the growing problem of antibiotic-resistant bacteria.

29 Oct 2024

Unveiling the Molecular Mechanisms of CRISPR-Cas10's Cellular Shutdown

CRISPR-Cas9 can elegantly and precisely cut away any desired region of DNA and has long been compared to a type of genetic scissors.

29 Oct 2024

Innovative Genomic Technology Uncovers Mechanisms of Marjolin's Ulcer

Researchers utilized specialized genomic technology at the University of Calgary to enhance our understanding of Marjolin's ulcer (MU), a rare, highly aggressive skin cancer that affects chronic wounds that can often arise from established scars like those caused by severe burns.

29 Oct 2024

Study Links Extracellular Vesicles to Blood Vessel Damage in Cancer

A landmark study led by WEHI and La Trobe University has found a potential new diagnostic marker that could be used to better detect the level of tissue damage in our bodies.

29 Oct 2024

F-Actin Accumulation Impairs Brain Function in Aging Fruit Flies

Humans aren't the only ones who grow forgetful as they age -; fruit flies do, too. But because fruit flies have a lifespan of only about two months, they can be a useful model for understanding the cognitive decline that comes with aging.

29 Oct 2024

C. elegans Model Revolutionizes Search for Amyloid Inhibitors

An international team led by researchers at the University of Toronto has developed an efficient and robust system, using the C. elegans nematode, to screen for compounds that can stop the growth of amyloid proteins.

29 Oct 2024

New Insights Into the Role of p53 in Intestinal Inflammation

A group of scientists from Charité – Universitätsmedizin and the Berlin Institute for Medical Systems Biology of the Max Delbrück Center have provided fresh insight into the pathophysiology of ulcerative colitis an inflammatory bowel disease that affects an estimated five million people globally and is associated with a higher risk of colon cancer.

28 Oct 2024

Key Regulator of Heart Repair

UCLA researchers identified the protein GPNMB as a key regulator in the heart’s healing process following a heart attack.

28 Oct 2024

Novel Mechanism for GRB2-SOS1-Mediated Liquid-Liquid Phase Separation

Researchers at Tokyo Metropolitan University have discovered new details about how the proteins GRB2 and SOS1 in cells transmit signals from membrane receptors to nuclei.

28 Oct 2024

Study Reveals Impact of Genetic Mutations on Protein Localization

The team developed a high-throughput imaging platform to assess the influence of nearly 3,500 mutations on protein location. They found that roughly one in six disease-causing mutations led to proteins ending up in the wrong location in the cell.

28 Oct 2024

Groundbreaking Study Reveals New Insights into Fruit Fly Reproduction

You have likely not spent much time thinking about the uterus of the fruit fly, Drosophila melanogaster.

28 Oct 2024

Stem-Like CD4 T Cells Could Transform Cancer Treatment Strategies

Researchers at Winship Cancer Institute of Emory University have identified a novel type of immune cell, called the stem-like CD4 T cell, that plays a pivotal role in anti-tumor immunity.

28 Oct 2024

Monoclonal Antibody Market Set to Triple by 2033, Revolutionizing Disease Treatment

Recent advancements in monoclonal antibody engineering are reshaping disease treatment, focusing on safety, effectiveness, and addressing current medical needs.

28 Oct 2024

Cryo-EM Technology Paves the Way for Major Biological Discovery

Ben Orlando's research talk at MSU's Department of Biochemistry and Molecular Biology in 2019 laid the groundwork for a team effort that had been developing for decades.

25 Oct 2024

New Insights into How TRIM25 Fights RNA Viruses

Human bodies are attacked every single second of every day. The invading agents include bacteria, viruses, parasites, and toxins both living and non-living things that could impair how well bodies work.

25 Oct 2024

Zebrahub Offers Unprecedented Insight into Embryonic Development

When early cartographers undertook perilous expeditions to map unknown corners of the world with sextants, compasses, and hand-drawn diagrams, it's unlikely they imagined that someday anyone with an internet connection would have access to a seamless view of the entire planet from the comfort of their own home.

25 Oct 2024

Mobile Genetic Elements Alter Antagonistic Strategies of Gut Bacteria

Bacteria evolve rapidly in the human gut by sharing genetic elements with each other. Bacteriodales is a prolific order of gut bacteria that trade hundreds of genetic elements.

25 Oct 2024