Dementia News and Research

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Dementia is not a specific disease. It is a descriptive term for a collection of symptoms that can be caused by a number of disorders that affect the brain. People with dementia have significantly impaired intellectual functioning that interferes with normal activities and relationships. They also lose their ability to solve problems and maintain emotional control, and they may experience personality changes and behavioral problems, such as agitation, delusions, and hallucinations.

Scientists discover two ways to preserve diseased upper motor neurons in ALS

Northwestern Medicine scientists have discovered two ways to preserve diseased upper motor neurons that would normally be destroyed in ALS, based on a study in mice. Upper motor neurons initiate movement, and they degenerate in ALS.

24 Feb 2023

Mount Sinai researchers illuminate the role of DNA methylation in Alzheimer's disease

Mount Sinai researchers have published a study in Alzheimer's & Dementia: The Journal of the Alzheimer's Association that sheds new light on the role of DNA methylation in Alzheimer's disease (AD).

23 Feb 2023

Beef, pork, chicken, and other meats contain new antioxidants, analysis reveals

Imidazole dipeptides (IDPs), which are abundant in meat and fish, are substances produced in the bodies of various animals, including humans, and have been reported to be effective in relieving fatigue and preventing dementia.

17 Feb 2023

"Poisoned" form of a protein could set off events that encourage cancer growth

Scientists at Scripps Research, with collaborators in Japan, have discovered how a "poisoned" form of a protein could set off a cascade of events that encourage the growth of some cancers.

17 Feb 2023

DZNE scientists discover major role of centrosome in neuronal migration

Researchers from the DZNE have solved an important puzzle in neurobiology: the wiring and the movement of nerve cells are interwoven, but separately controlled.

16 Feb 2023

WashU researcher receives NIH grant to study a poorly understood protein linked to ALS

The relentless neurological disease amyotrophic lateral sclerosis (ALS) eventually shuts down the entire body, but the devastation starts at a molecular level.

14 Feb 2023

Marine plankton samples can help understand the link between ocean pollution and chronic illnesses

Using samples from an almost century-old, ongoing survey of marine plankton, researchers at University of California San Diego School of Medicine suggest that rising levels of manmade chemicals found in parts of the world's oceans might be used to monitor the impact of human activity on ecosystem health, and may one day be used to study the connections between ocean pollution and land-based rates of childhood and adult chronic illnesses.

9 Jan 2023

Ultrafast, highly sensitive detection of proteins using simple laser irradiation

Protein detection based on antigen–antibody reaction is vital in early diagnosis of a wide range of diseases. How to effectively detect proteins, however, has frequently bedeviled researchers.

4 Jan 2023

Analyzing progenitor fate and dynamics long after embryonic development

According to Johns Hopkins Medicine researchers, they have devised a computer model called quantitative fate mapping that looks back in time to track the origin of cells in a fully grown organism.

14 Dec 2022

RNA-targeting strategy to repair the genetic cause of ALS and dementia

Researchers at UF Scripps Biomedical Research have created a potential treatment for a major factor in the development of ALS and dementia that functions by removing disease-causing RNA segments.

24 Nov 2022

Revitalized immune cells improve waste removal from the brain

Damaged protein clusters in the brain are a hallmark of many neurodegenerative diseases, including Parkinson’s, Alzheimer’s, and others. Although they have made significant efforts, scientists have only partially succeeded in finding treatments for these conditions by removing these toxic clusters.

11 Nov 2022

Brain-resident and recruited macrophages exhibit diverging responses

Prof. Kiavash Movahedi (VUB, VIB) headed a group that outlined how the immune system responds to infections entering the brain. The results offer new information on host-pathogen interactions as well as the long-term effects of brain infections.

14 Oct 2022

Gut microbiome’s influence on how lifestyle affects dementia risk

A recent Baycrest study points to the possibility that the gut microbiome influences how nutrition and exercise impact brain health and dementia risk. Physicians and researchers could be able to improve dementia prevention efforts with the use of this knowledge.

13 Oct 2022

“Junk” DNA could provide access to innovative treatments for neurological conditions

The breakthrough study from the University of Sheffield’s Neuroscience Institute and Healthy Lifespan Institute offers critical new insights into the so-called junk DNA, or DNA that was previously believed to be unimportant to the coding of the genome, and how it affects neurological disorders like Motor Neuron Disease (MND) and Alzheimer’s.

29 Sep 2022

Special blood vessels may protect whales from brain damage while swimming

Special blood vessels in whale brains may protect them from pulses, caused by swimming, in their blood that would damage the brain, new UBC research has suggested.

23 Sep 2022

Novel molecular mechanism of focal adhesion kinase inhibition in HD

Principal researchers at the Brain Science Institute (BSI) of the Korea Institute of Science and Technology were said to have discovered substantially decreased activity of focal adhesion kinase (FAK) proteins that play a significant role in neurite motility and proper synapse formation in HD patients’ brain tissues.

19 Sep 2022

Dementia News and Research

Scientists discover two ways to preserve diseased upper motor neurons in ALS

Mount Sinai researchers illuminate the role of DNA methylation in Alzheimer's disease

Beef, pork, chicken, and other meats contain new antioxidants, analysis reveals

"Poisoned" form of a protein could set off events that encourage cancer growth

DZNE scientists discover major role of centrosome in neuronal migration

WashU researcher receives NIH grant to study a poorly understood protein linked to ALS

Marine plankton samples can help understand the link between ocean pollution and chronic illnesses

Ultrafast, highly sensitive detection of proteins using simple laser irradiation

Analyzing progenitor fate and dynamics long after embryonic development

RNA-targeting strategy to repair the genetic cause of ALS and dementia

Revitalized immune cells improve waste removal from the brain

Brain-resident and recruited macrophages exhibit diverging responses

Gut microbiome’s influence on how lifestyle affects dementia risk

“Junk” DNA could provide access to innovative treatments for neurological conditions

Special blood vessels may protect whales from brain damage while swimming

Novel molecular mechanism of focal adhesion kinase inhibition in HD

Optogenetic control of mitochondria–lysosome contacts induce mitochondrial fission with spatiotemporal accuracy

Researchers reveal novel mechanism that links interferon activation and α-synuclein function in neurons

New bacterial tool improves drug production in bacterial cells

Researchers get funding to develop a vaccine against ALS disease

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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