Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

Cancer invasion and migration can be suppressed by manipulating stiffness of cell membrane

A research collaboration has found that cancer invasion and migration in mice can be inhibited by controlling the stiffness of the cell membrane.

10 Nov 2021

Cancer cells change their shape and migration modes more often, says research

Recent research from the Oregon State University shows how malignant cells change their shape and migration techniques to attack various tissues.

29 Oct 2021

Study provides novel insights into how cells move through the body

Recent research published in eLife revealed that cells can control their capability to migrate throughout the body with the help of a protein named fascin.

29 Oct 2021

Genetic biomarker test could help personalize therapy for men with high-risk prostate cancer

A new meta-analysis finds that a genetic biomarker test accurately predicts how men with high-risk prostate cancer will respond to treatment with radiation and hormone therapy.

26 Oct 2021

Virginia Tech scientists receive $1 million grant to predict the mechanics of living cells

With advances in deep learning, machines are now able to "predict" a variety of aspects about life, including the way people interact on online platforms or the way they behave in physical environments.

15 Oct 2021

Molecular atlas of small cell lung cancer reveals signatures of metastasis and immunosuppression

Imagine you're about to go on a cross-country trip, stopping at spots along the way to admire local attractions.

15 Oct 2021

Study explores molecular mechanism behind cell homing

Research reveals how stem cells slow down their rolling inside the circulatory system by developing long tethers that bind to the inner surfaces of blood vessels.

8 Oct 2021

Researchers uncover previously unknown interactions between proteins that drive cancers

In three studies from the Cancer Cell Map Initiative, researchers uncovered previously unknown interactions between proteins that drive cancer and combined this new data to generate a map of protein pathways informing cancer outcomes.

1 Oct 2021

Scientists create a three-dimensional pancreatic cancer tumor model

Researchers generated a 3D pancreatic cancer tumor model in the lab, merging a bioengineered matrix and patient-derived cells.

28 Sep 2021

Tumor suppressor protein binding to RNA also binds DNA, says study

Scientists from the Medical University of South Carolina earlier displayed how hnRNP E1 attaches to metastatic-linked RNAs to prevent their translation.

27 Sep 2021

Novel T cells reside in lymph nodes and offer protection against melanoma

Immunotherapy is an advancing field but there is limited knowledge on the immunity to metastatic tumors in locations like lymph nodes.

20 Sep 2021

New treatment developed from plant virus could keep metastatic cancers at bay

Using a virus that grows in black-eyed pea plants, nanoengineers at the University of California San Diego developed a new treatment that could keep metastatic cancers at bay from the lungs.

From UC San Diego 15 Sep 2021

Eosinophils combat cancer metastases in the lungs, says research

Recent research at Tel Aviv University identified that eosinophils—a kind of white blood cells—are recruited for the fight against cancer metastases in the lungs.

15 Sep 2021

Study finds the link between circular RNA and alternative splicing in gastric cancer

At the Chinese Academy of Sciences, scientists have now come up with a mechanism used by circular RNA to inhibit the metastasis of gastric cancer cells.

23 Aug 2021

Study discovers actionable DNA errors remain stable over time

A single analysis of the entire tumor DNA is mostly sufficient to identify all DNA errors that might be relevant for treating metastatic cancer.

11 Aug 2021

Research provides a detailed 'proteogenomic' view of lung squamous cell carcinoma

Lung cancer remains the leading cause of cancer-associated death in the United States and worldwide. Patients with a subtype called lung adenocarcinoma (LUAD) have benefited from the development of new targeted medicines, but the search for effective new therapies for another subtype called lung squamous cell carcinoma (LSCC) has largely come up short.

6 Aug 2021

Study unravels vital mechanism coordinating cell division and adhesion in humans

A new study by scientists has unraveled a crucial mechanism that coordinates the processes of cell division and adhesion in humans.

29 Jul 2021

Pushing organ-on-a-chip microdevices to new levels to improve ovarian cancer treatment

In the evolving field of cancer biology and treatment, innovations in organ-on-a-chip microdevices allow researchers to discover more about the disease outside the human body.

26 Jul 2021

Study unravels the biomechanical, biophysical response of cancer cells to drugs

A new study reports the use of single-cell, force spectroscopy methods to probe biophysical and biomechanical kinetics of cancer cells.

21 Jul 2021

Atomic force spectroscopy probes cellular biomechanics in response to drugs in hypoxia

Oncotarget published "Dynamic cellular biomechanics in responses to chemotherapeutic drug in hypoxia probed by atomic force spectroscopy" which reported that by exploiting single-cell, force spectroscopy methods, the authors probed biophysical and biomechanical kinetics of brain, breast, prostate, and pancreatic cancer cells with standard chemotherapeutic drugs in normoxia and hypoxia over 12-24 hours.

20 Jul 2021