Psychiatry News and Research

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Psychiatry is the treatment, study and prevention of mental disorders.

New research offers the most insight on the genetic basis of schizophrenia

According to the World Health Organization, schizophrenia is a serious psychiatric condition that begins in late adolescence or early adulthood and affects one in every 300 persons globally.

3 May 2022

Astrocyte abnormalities may play a pivotal role in causing ASD symptoms

Abnormalities in a type of brain cell called astrocytes may play a pivotal role in causing some behavioral symptoms of autism spectrum disorders, according to a preclinical study by Weill Cornell Medicine investigators.

22 Apr 2022

New research shows significant variations in B-cells in women with PPD

Jerry Guintivano, PhD, of the University of North Carolina School of Medicine, led an exclusive transcriptome-wide association research that showed substantial changes in B-cells in women with postpartum depression, with pathway observations indicating modified B-cell activation and insulin resistance.

19 Apr 2022

Research associates depressive diseases and deformability of blood cells

For the first time, a study conducted by the TU Dresden and the University of Zurich in collaboration with the Max Planck Institute for the Science of Light finds a relationship between depressive disorders and mechanical features of all main blood cell types.

19 Apr 2022

New scalable method to advance maturation of human pluripotent stem cell-derived cardiomyocytes

A Mount Sinai-led team has developed a reproducible and scalable method to advance maturation of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs)-;cells that support heart muscle contraction, generated in the lab from human stem cell lines-;which researchers say will improve approaches for disease modeling, regenerative therapies, and drug testing.

8 Apr 2022

Researchers identify a large number of specific genes associated with schizophrenia

What is the role of genetics in schizophrenia? To address this question, an international group of researchers led by Charité – Universitätsmedizin Berlin and Cardiff University developed and conducted the largest-ever genetic study on schizophrenia.

8 Apr 2022

Gene mutation influences autism development, study finds

A research team discovered that interruption of a circadian clock gene may be implicated in the formation of autism spectrum disorder.

25 Mar 2022

Transcriptomic analysis of Alzheimer's patients reveals early organelle dysfunction in astrocytes

An international group of researchers led by the UAB analyzed the genes that are expressed in neurons and astrocytes based on data from 800 individuals and compared what happens in Alzheimer's patients and in people without diagnosed dementia.

21 Mar 2022

Study discovers common genetic factors between depression and Alzheimer’s disease

Recent research discovered common genetic factors between depression and AD.

18 Feb 2022

Scientists use genetically informed brain atlases to identify hundreds of genomic loci

An international team of scientists has used atlases of the human brain informed by genetics to identify hundreds of genomic loci. Loci is plural for locus, and in genetics indicates the physical location of a gene or variant on a chromosome.

From UC San Diego 8 Feb 2022

Researchers provide first evidence of the gene-environment interaction in the social dysfunctions typical of autistic disorders

Autism spectrum disorders are characterized by a wide range of behavioral issues.

2 Feb 2022

Scientists discover hotspots in the 'dark genome' associated with schizophrenia and bipolar disorder

Scientists investigating the DNA outside our genes - the 'dark genome' - have discovered recently evolved regions that code for proteins associated with schizophrenia and bipolar disorder.

24 Dec 2021

Multiple changes in brain cells during embryonic development may contribute to schizophrenia

Multiple changes in brain cells during the first month of embryonic development may contribute to schizophrenia later in life, according to a new study by Weill Cornell Medicine investigators.

17 Dec 2021

Detecting high-impact rare genetic variants in individuals with severe schizophrenia

New research published in the Proceedings of the National Academy of Sciences shows that examining genetic mutations in individuals with severe schizophrenia can improve the ability to detect disease-associated rare genetic variants.

15 Dec 2021

Study provides new insight into the genetics of severe schizophrenia

Columbia University researchers have determined that individuals who suffer from the most severe form of schizophrenia have a significantly higher number of rare mutations than more typical forms of the illness.

14 Dec 2021

Study elucidates the role of genomics in obsessive-compulsive disorder

According to recent research carried out by the researchers from the Icahn School of Medicine at Mount Sinai, both rare and commonly seen differences in the DNA letters threaded along an individual’s chromosomes can elucidate about a third of the risk for being diagnosed with obsessive-compulsive disorder (OCD).

19 Nov 2021

Genetic liability to mental health conditions may affect a person's choice of residence

Living in cities has been highlighted as an environmental risk factor for schizophrenia and, to a lesser extent, other mental health conditions. However, few studies have explored genetic effects on the choice of residence.

28 Oct 2021

Microglial cells join together to break down toxic proteins more quickly

To break down toxic proteins more quickly, immune cells in the brain can join together to form networks when needed. This is shown by a joint study of the University of Bonn, the German Center for Neurodegenerative Diseases, and the Institut François Jacob in France.

23 Sep 2021

Polygenic risk scores are no better in predicting disease, says study

Scientists went through the records of more than 8,000 schizophrenia patients and identified a tool used for assessing an individual’s genetic risk for a disease.

8 Sep 2021

UMSOM study suggests a genetic basis behind instantaneous human compatibility

Have you ever met someone you instantly liked, or at other times, someone who you knew immediately that you did not want to be friends with, although you did not know why?

2 Sep 2021