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Cocaine addiction: Impact of genetic mutations elucidated

Cocaine addiction is a chronic disorder with a high rate of relapse for which no effective treatment is currently available.

28 Sep 2020

Stem cells can repair parkinson's-damaged circuits in mouse brains

The mature brain is infamously bad at repairing itself following damage like that caused by trauma or strokes, or from degenerative diseases like Parkinson's.

28 Sep 2020

Researchers sequence the genome of original penicillin strain

For the first time, scientists have sequenced the genome of Alexander Fleming’s penicillin mould and compared it to the later models.

25 Sep 2020

Scientists create the first atlas of human heart cells

Ka-thump. Ka-thump. Ka-thump. Though we barely notice it most of the time, the steady beating of a human heart is an amazingly complex performance.

25 Sep 2020

Researchers discover how antibiotic resistance genes spread via plasmids

For the first time, researchers have discovered how antibiotic resistance genes are spreading, at a continental scale, via bacterial plasmids in the hospital superbug, Klebsiella pneumoniae.

25 Sep 2020

Researchers analyze individual cells to build an atlas of the human heart

Scientists have created a cellular and molecular map of the healthy human heart, to understand how this vital organ functions, and to shed light on what goes wrong in cardiovascular disease.

25 Sep 2020

New data shows immunotherapy is beneficial for patients with gastric, esophageal cancers

New data presented at ESMO 2020 have shown that immunotherapy is beneficial for patients with gastric and esophageal cancers who currently have poor survival. (1-3)

24 Sep 2020

Research finds air pollution particles in the placentas of women

Pollution particles, including metals, have been found in the placentas of fifteen women in London, according to research led by Queen Mary University of London.

24 Sep 2020

Combination treatment improves outcomes in advanced kidney cancer patients

An immunotherapy agent combined with a tyrosine kinase inhibitor drug significantly improved progression-free survival and reduced the risk of death compared to a single agent treatment in advanced kidney cancer patients, according to first results of a phase 3 clinical trial. The pivotal study could lead to a new treatment option for patients with metastatic kidney cancer.

24 Sep 2020

ADHD study reveals genetic differences between African Americans and people of European ancestry

Researchers from Children's Hospital of Philadelphia (CHOP) have shown there may be key genetic differences in the causes of attention-deficit hyperactivity disorder (ADHD) between African Americans and people of European ancestry, which may play an important part in how patients of different ethnic backgrounds respond to treatments for this condition. The findings were published online by the journal Scientific Reports.

23 Sep 2020

Study identifies genetic factors linked to higher risk of capecitabine-induced hand-foot syndrome

Capecitabine is a chemotherapy drug used for breast and colorectal Cancer cancer. It can extend survival rate by nearly 10%.

22 Sep 2020

New technology to unlock the secrets of plant genomes in high resolution

The genomes of all higher life forms are stored in the cell nucleus on chromosomes. Chromosomes are composed of strands of the DNA molecule.

22 Sep 2020

Elderly patients face higher risk of severity and death from COVID-19

SARS-CoV-2 can infect people of any age. However, elderly people face a greater risk of severity and death when compared to younger patients.

22 Sep 2020

New methods to increase anti-cancer activity of T cells

Scientists have gained a deeper insight into the complexity of the surrounding in which T cells flourish.

18 Sep 2020

Researchers develop highly scalable and accurate antibody test for COVID-19

An antibody test for the virus that causes COVID-19, developed by researchers at The University of Texas at Austin in collaboration with Houston Methodist and other institutions, is more accurate and can handle a much larger number of donor samples at lower overall cost than standard antibody tests currently in use.

14 Sep 2020

Researchers identify the cause for Parkinson's disease and potential treatments

In a seven-year research effort, an international team of scientists has clarified the cause for certain genetic forms of Parkinson's disease, and has identified potential pharmacological treatments.

14 Sep 2020

Inherited variation in GATA3 gene associated with relapse in children with leukemia

Scientists at St. Jude Children's Research Hospital are investigating the inherited genetics of childhood leukemia and how particular gene variations can affect treatment outcomes. The research showed that an inherited variation in the GATA3 gene strongly influences early response to chemotherapy and is linked to relapse in children with acute lymphoblastic leukemia (ALL).

14 Sep 2020