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Researchers develop novel technology to detect cancer biomarkers

A new way of identifying cancer biomarkers has been developed by researchers at Lund University in Sweden. The new technology allows very sensitive, quick and cost-effective identification of cancer biomarkers. The research is published in Nature Communication Biology.

16 Jul 2020

Imaging mass spectrometry identifies tumor markers for head and neck squamous cell carcinoma

Volume 11, Issue 28 of Oncotarget features "Lipid and protein tumor markers for head and neck squamous cell carcinoma identified by imaging mass spectrometry" by Schmidt et. al. which reported that the authors used MALDI imaging mass spectrometry and immunohistochemistry to seek tumor-specific expression of proteins and lipids in HNSCC samples.

15 Jul 2020

UVA scientists identify oncogene responsible for glioblastoma

Scientists have identified an oncogene (a cancer-causing gene) responsible for glioblastoma, the deadliest brain tumor.

15 Jul 2020

Golgi membrane protein drives growth and invasion of breast cancer

The cover for issue 28 of Oncotarget features Figure 5, "TMEM165 expression levels alters N-linked glycosylation," by Murali, et al., and reported that the TMEM165 protein was not detected in non-malignant matched breast tissues and was detected in invasive ductal breast carcinoma tissues by mass spectrometry.

15 Jul 2020

Dual inhibitor therapy may be safer for patients with chronic lymphocytic leukemia

Chronic lymphocytic leukemia (CLL) is the most common leukemia in adults. One in four new leukemia cases are CLL.

15 Jul 2020

New radiopharmaceutical offers precise diagnosis and treatment of prostate cancer in preclinical studies

Researchers have developed a new pair of agents that show exceptional effectiveness for precision diagnosis and treatment of prostate cancer in preclinical studies.

14 Jul 2020

Novel approach to analyze organ development through gene analysis in single cells

When cells develop, variations in the interaction of genes of an individual determine their fate. Such variations in genetic interactions can make the individual’s cells powerful against infection from viruses or enable the immune cells to kill the tumor cells.

14 Jul 2020

PET radiotracer is safe and effective for imaging malignant brain tumors

A first-in-human study presented at the Society of Nuclear Medicine and Molecular Imaging 2020 Annual Meeting has demonstrated the safety, favorable pharmacokinetic and dosimetry profile of 64Cu-EBRGD, a new, relatively long-lived PET tracer, in patients with glioblastomas.

14 Jul 2020

Nano-radiomics uses imaging data to assess changes in the tumor microenvironment

Research has shown that the tumor microenvironment (TME) can help cancers grow and evade the immune response.The TME has even been shown to inhibit cellular immunotherapy, a novel form of treatment in which the cells of a patient's immune system are re-engineered in the lab to attack cancer cells.

14 Jul 2020

Researchers develop new immunotherapy that prevents reoccurrence of breast cancer

New immunotherapy developed by researchers at Northwestern University dramatically extends the survival time of mice with triple-negative breast cancer, one of the most aggressive and difficult-to-treat forms of breast cancer.

14 Jul 2020

Total-body dynamic PET scans can produce high-quality images of metastatic cancer

Results from the first study using uEXPLORER to conduct total-body dynamic positron emission tomography (PET) scans in cancer patients show that it can be used to generate high-quality images of metastatic cancer.

14 Jul 2020

Targeted radionuclide therapy creates a favorable tumor microenvironment in prostate cancer

Targeted radionuclide therapy has been found to create a favorable tumor microenvironment in prostate cancer that improves the effectiveness of immunotherapies.

14 Jul 2020

New technology generates immune response by delivering antigens to APCs in the spleen

Red blood cells do more than shuttle oxygen from our lungs to our organs: they also help the body fight off infections by capturing pathogens on their surfaces, neutralizing them, and presenting them to immune cells in the spleen and liver.

14 Jul 2020

Fatty acid can kill cancer cells, study shows

Researchers have demonstrated that a fatty acid called dihomogamma-linolenic acid, or DGLA, can kill human cancer cells.

13 Jul 2020

Genomics study in Black Americans could lead to precision prostate cancer therapies

Black men in the United States are known to suffer disproportionately from prostate cancer, but few studies have investigated whether genetic differences in prostate tumors could have anything to do with these health disparities.

13 Jul 2020

New drug enables the immune system to attack ovarian cancer, TGen study shows

A drug known as SP-2577 could help enable the body's own immune system to attack ovarian cancer, according to a study led by the Translational Genomics Research Institute, an affiliate of City of Hope.

13 Jul 2020

Scientists report detailed proteomic analysis of human lung adenocarcinoma

A team of Chinese scientists from the State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica under the Chinese Academy of Sciences, the State Key Laboratory of Proteomics, National Center for Protein Sciences (Beijing), National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, and Shanghai Jiao Tong University, recently reported a comprehensive proteomic analysis based on 103 Chinese patients with lung adenocarcinoma (LUAD), a leading cause of death among all types of cancer worldwide.

10 Jul 2020

Study shows sex hormones alter the behavior of non-sex organs

In one of the first studies addressing the role of sex hormones' impact on stem cells in the gut, scientists outline new insights showing how a steroidal sex hormone, that is structurally and functionally similar to human steroid hormones, drastically alters the way intestinal stem cells behave, ultimately affecting the overarching structure and function of this critical organ.

10 Jul 2020

Expansion stress promotes immunosuppression and enhances growth of breast cancer cells

Expansion stress can have an alarming impact on breast cancer cells by creating conditions that could lead to dangerous acceleration of the disease, an interdisciplinary team of University of Alabama at Birmingham researchers has found.

10 Jul 2020

Study shows engineered natural killer immune cells can directly kill tumor cells

According to a study, researchers have successfully designed natural killer immune cells that destroy head and neck tumor cells in mice.

8 Jul 2020

Tumor News and Research

Researchers develop novel technology to detect cancer biomarkers

Imaging mass spectrometry identifies tumor markers for head and neck squamous cell carcinoma

UVA scientists identify oncogene responsible for glioblastoma

Golgi membrane protein drives growth and invasion of breast cancer

Dual inhibitor therapy may be safer for patients with chronic lymphocytic leukemia

New radiopharmaceutical offers precise diagnosis and treatment of prostate cancer in preclinical studies

Novel approach to analyze organ development through gene analysis in single cells

PET radiotracer is safe and effective for imaging malignant brain tumors

Nano-radiomics uses imaging data to assess changes in the tumor microenvironment

Researchers develop new immunotherapy that prevents reoccurrence of breast cancer

Total-body dynamic PET scans can produce high-quality images of metastatic cancer

Targeted radionuclide therapy creates a favorable tumor microenvironment in prostate cancer

New technology generates immune response by delivering antigens to APCs in the spleen

Fatty acid can kill cancer cells, study shows

Genomics study in Black Americans could lead to precision prostate cancer therapies

New drug enables the immune system to attack ovarian cancer, TGen study shows

Scientists report detailed proteomic analysis of human lung adenocarcinoma

Study shows sex hormones alter the behavior of non-sex organs

Expansion stress promotes immunosuppression and enhances growth of breast cancer cells

Study shows engineered natural killer immune cells can directly kill tumor cells

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