Genomic News and Research

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Study reveals the relationship between genome folding and cellular functions

According to a study, the 3D structure of the human genome is fundamental to provide a quick and strong inflammatory response.

9 Jun 2020

Researchers identify a promising biomarker to screen stem cell quality

Published recently in the Stem Cells journal, a new study addresses a major issue that has been challenging the human mesenchymal stem cells (hMSCs) therapy.

9 Jun 2020

DNA damage and repair jointly shape mutational signatures

A collaborative project between the Center for Genome Integrity, within the Institute for Basic Science, and the Dundee School of Life Sciences, the EMBL's European Bioinformatics Institute, and the Wellcome Sanger Institute have screened almost 163,000 DNA mutations in 2,700 C. elegans roundworms to shed light on DNA damage.

9 Jun 2020

Study sheds light on "repurposed" enzymatic reactions

Researchers have identified key ingredients for producing high-value chemical compounds in an environmentally friendly fashion: repurposed enzymes, curiosity, and a little bit of light.

9 Jun 2020

Study reveals new insight on vaccines and antimicrobials

Bacteria are known to be versatile living organisms capable of colonizing a wide variety of tissues, hosts, or environments inside a host.

9 Jun 2020

Genome rewiring could help explain evolution of multi-cellular organisms

InsideOutBio expert Dr Alan Herbert has explained a pioneering research in a paper recently published online by the Royal Society Open Science journal.

9 Jun 2020

Genomic research can help combat COVID-19

Next-generation sequencing of the COVID-19 virus is providing powerful metagenomic data, which, combined with clinical data, will inform the search for effective treatments, as reported in the peer-reviewed journal Pediatric Allergy, Immunology, and Pulmonology.

5 Jun 2020

Human protein plays crucial role in transcription and genome integrity

Researchers from the University of Seville and Cabimer discover that the UAP56/DDX39B protein remove DNA-RNA hybrids from the genome.

5 Jun 2020

Fate-seq technique shows structural differences between COVID-19 and SARS viruses

Scientists have discovered certain segments of the genetic codes of the SARS and COVID-19 viruses that may support the lifecycle of the viruses.

4 Jun 2020

Review reveals exceptions to the purported rules of sex chromosome evolution theory

For nearly a century, biologists have modeled the evolution of sex chromosomes--the genetic instructions that primarily determine whether an individual will develop into a male or female (or a certain mating type)--resulting in an impressive theoretical framework.

4 Jun 2020

Recombineering technique may overcome barriers in bacterial engineering

Genetic engineering of bacteria has transformed contemporary medicine, from bacterial-based insulin to a deeper insight into infectious diseases.

From Harvard Medical School 1 Jun 2020

gnomAD Consortium releases first set of discoveries on human genetic variation

For the last eight years, the Genome Aggregation Database Consortium (and its predecessor, the Exome Aggregation Consortium, or ExAC), has been working with geneticists around the world to compile and study more than 125,000 exomes and 15,000 whole genomes from populations around the world.

29 May 2020

ADHD-associated genetic variants have reduced progressively in human lineage

According to a study published in the Scientific Reports journal, the frequency of genetic variants linked to attention-deficit/hyperactivity disorder (ADHD) has reduced progressively in the evolutionary human lineage from the Palaeolithic to the present day.

29 May 2020

Damped circadian oscillations observed in the absence of KaiA protein in cyanobacterium

Circadian rhythms are driven by a highly autonomous, self-sustaining circadian clock in our cells, telling us when to sleep or wake up in a 24-hour cycle.

27 May 2020

New sequencing method helps map the spatial arrangement of DNA

A sequencing technique helps to map the spatial arrangement of DNA in the cell nucleus, revealing which regions of the genome are at greater risk of mutation.

27 May 2020

Environmental Contaminants Alter Gut Microbiome

The microbes that inhabit our bodies are influenced by what we eat, drink, and breathe and most of us are exposed to environmental contaminants.

22 May 2020

Cross-neutralization of SARS and COVID-19 coronaviruses by an antibody

An antibody first identified in a blood sample from a patient who recovered from Severe Acute Respiratory Syndrome in 2003 inhibits related coronaviruses, including the cause of COVID-19.

19 May 2020

Study shows coronavirus does not induce cross-protective immune antibodies

According to researchers, patients infected with severe acute respiratory syndrome coronavirus (SARS-CoV) or SARS-CoV-2 generate antibodies that adhere to the other coronavirus; however, the cross-reactive antibodies are not actually cross-protective, as far as cell-culture experiments are concerned.

19 May 2020

Researchers develop a reliable technique for assessing the role of lncRNAs

The discovery of a huge number of long non-protein coding RNAs, aka lncRNAs, in the mammalian genome was a major surprise of the recent large-scale genomics projects.

18 May 2020

Researchers Find New Breast Cancer Gene In Young People

Over the years, our knowledge of diseases has improved, and several hereditary gene variants have been found that may predispose to the development of cancer.

18 May 2020