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Study shows how mutational signatures are shaped by DNA repair pathways

A research team has examined more than 2700 genomes from C. elegans worms to gain a better understanding on the causes responsible for mutations.

4 May 2020

Nanostimulators Boost Stem Cells For Muscle Repair

In medicine, a treatment for patients whose muscles are damaged from lack of oxygen would be to invigorate them with an injection of their own stem cells.

4 May 2020

New Discovery Explains How The Prostate Gland Regenerates Itself

The standard treatment for men with advanced prostate cancer is androgen-deprivation therapy. This article looks at how the prostate gland regenerates.

1 May 2020

Modifications to gut microbiome could slow cancer growth in smokers

Changes to the gut microbiome interacted with the immune system to slow the growth of cancer in mice exposed to cigarette smoke, according to research that was selected for presentation at Digestive Disease Week 2020.

30 Apr 2020

'Backpacks' Boost Immune Cells' Ability To Kill Cancer

Macrophages are immune cells that patrol the body looking for potential threats like viruses, bacteria, and cancer cells, and engulf and destroy them.

30 Apr 2020

Immune System Changes Occur Early In Development Of Multiple Myeloma

Before multiple myeloma becomes a malignant disease, the collection of immune system cells and signal carriers amid the tumor cells undergo dramatic shifts.

29 Apr 2020

Research on rare molecule aims to improve treatments for cancer, HIV

Stanford University chemist Paul Wender and his colleagues are working to improve treatments for cancer, HIV and Alzheimer's - and they are betting that a drab, weedy marine invertebrate is the means to achieving that end.

28 Apr 2020

Def gene essential for maintaining liver homeostasis and regeneration capacity

Hepatocytes are responsible for diverse metabolic activities in a liver. Proper ribosome biogenesis is essential to sustain the function of hepatocytes.

28 Apr 2020

Pancreatic tumors hijack basic cell mechanism for immune evasion

Pancreatic cancer cells use a normal waste removal process to hide tags on their surfaces that would otherwise let the immune system destroy them, a new study finds. Published online April 22 in Nature, the study results help to answer a longstanding question: why are pancreatic cancers so resistant to immunotherapies, which use the body's own immune defenses to fight cancer?

24 Apr 2020

Combination therapy encourages innate immune cells to eat GBM tumors

A combination of immunotherapy agents that encourages some immune cells to eat cancer cells and alert others to attack tumors put mice with a deadly type of brain cancer called glioblastoma into long-term remission, a new study led by UT Southwestern scientists suggests.

24 Apr 2020

A New Therapeutic Target Turns The Immune System Against Lymphoma

Non-Hodgkin lymphoma (NHL) is a group of cancers that originate in the lymph nodes and affect white blood cells of the immune system called B cells.

24 Apr 2020

Study sheds light on the regulation of microRNAs

In all the organisms, including humans, proteins are encoded by genes and these proteins, in turn, control the body’s diverse specific cellular functions.

24 Apr 2020

Scientists find gene signature linked to worst prognosis in rare uterine cancer

Women who don't survive a rare and aggressive uterine cancer called uterine serous carcinoma, have high expression of a group of 73 genes, a score scientists say can help identify these women and improve their outcome.

22 Apr 2020

Study shows how tumor cells respond to nutrient deficiency

Some solid tumors have a very high growth rate, which often leads to a lack of vascularization due to the impossibility to develop, at the same time, the blood vessels that accompany and nourish it.

22 Apr 2020

New study could lead to effective immunotherapy treatments for cancer patients

According to a study recently published in the eLife journal, researchers have devised a new method to chart the molecules present on tumor cells that indicate their presence to the immune system.

22 Apr 2020

Discovery marks a critical step toward developing new anti-cancer drugs

A team of scientists led by the University of Michigan Rogel Cancer Center and Case Comprehensive Cancer Center has identified the binding site where drug compounds could activate a key braking mechanism against the runaway growth of many types of cancer.

21 Apr 2020

Researchers use genome-wide CRISPR technology to identify leukemia's weakness

A team of researchers at University of California San Diego School of Medicine and Moores Cancer Center used CRISPR technology to identify key regulators of aggressive chronic myeloid leukemia, a type of cancer that remains difficult to treat and is marked by frequent relapse.

From UC San Diego 21 Apr 2020

Cancer Drug Resistance Study Raises Immune Red Flags

Sooner or later, most cancer patients develop resistance to chemotherapy drugs designed to kill their cancer, forcing oncologists to seek alternatives.

20 Apr 2020

Personalized biohybrid microrobots for therapeutic cargo delivery

Tiny biohybrid robots on the micrometer scale can swim through the body and deliver drugs to tumors or provide other cargo-carrying functions.

8 Apr 2020

Study sheds light on the mechanism of cell division

There is no clear consensus on when exactly cells decide to divide. For four decades, the answer provided in the textbook was that this decision takes place in the initial phase of the existence of a cell—that is, soon after a mother cell divides into daughter cells.

7 Apr 2020