Laboratory News and Research

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Experts develop CRISPR-Cas9-mediated inheritance control in male mice

The world’s first CRISPR-Cas9 genetic editing-based strategy to regulate inheritance in mammals was declared nearly three years ago.

From UC San Diego 13 Jan 2022

Study finds gene family that regulates tissue-specific DNA methylation patterns

According to researchers at Salk, the CLASSY gene family controls which portions of the genome are turned off in a tissue-specific manner.

13 Jan 2022

Increasing the expression of a gene slows Alzheimer’s progression in mice

According to a recent research, enhancing the expression of one gene in cells that help the brain’s neurons, shields neurons in mouse models of Alzheimer’s disease.

13 Jan 2022

CSHL researchers spotlight the role of a previously little-known protein in leukemia

Acute myeloid leukemia (AML) is an aggressive cancer of white blood cells with few effective targeted therapies available to treat it.

12 Jan 2022

Scientists discover new Senp5S protein with crucial role in brain development

Understanding how the brain develops is crucial to formulating treatments and management protocols for a variety of developmental disorders, as well as degenerative neurological diseases. Right from the embryonic stage, brain development is facilitated by the differentiation of neurons (brain cells).

12 Jan 2022

Researchers reveal molecular and cellular mechanisms that lead to tertiary lymphoid structures formation

Tertiary lymphoid structures are formations that occur outside of the lymphatic system. They contain immune cells and are similar in structure and function to lymph nodes and other lymphoid structures.

12 Jan 2022

High resolution single tube reader

Ziath announce the Uno single tube reader – a powerful device packed with exciting features to make your sample management work with 2D barcoded tubes easier and faster.

From Ziath Ltd 12 Jan 2022

Research explains how E4 peptide exerts antifibrotic effect and what makes it so effective

A research team at the Medical University of South Carolina led by Carol Feghali-Bostwick, Ph.D., reports in the Journal of Clinical Investigation Insight that the E4 peptide reverses fibrosis, or scarring, in human and mouse tissues by activating an antifibrotic pathway that is common to all organ systems.

11 Jan 2022

Neurons derived from human stem cells can predict the cardinal features of psychiatric illness

In a breakthrough that holds significant promise for early diagnosis and better treatment of psychiatric illness, researchers have for the first time used neurons derived from human stem cells to predict the cardinal features of a psychiatric illness, such as psychosis and cognitive deficits in patients with schizophrenia.

11 Jan 2022

Study says plant microbiome influences health, survival, and fitness

The so-called plant microbiome—the microorganisms in a plant and its immediate environment—impacts plant health, survival, and fitness.

11 Jan 2022

Versatile method produces massive numbers of authentic human heart muscle cells

Scientists at the Leiden University Medical Centre (LUMC) successfully cultured human heart muscle cells on a large scale.

11 Jan 2022

Omicron variant hampers the effectiveness of vaccines and monoclonal antibodies, study shows

The Omicron variant was detected for the first time in South Africa in November 2021 and has since spread to many countries.

From Institut Pasteur 10 Jan 2022

CAR T cells produced in vivo using modified mRNA treat cardiac injury

A new study by researchers from the University of Pennsylvania shows that experimental immunotherapy can temporarily reprogram the immune cells of patients.

10 Jan 2022

Integrating Microplate Evaporators with Liquid Handling Robots

The Ultravap® Mistral family of microplate evaporators from Porvair Sciences are used in labs worldwide to remove the traditional laboratory ‘bottleneck’ of solvent evaporation from 12- to 384-well microplates and vials up to 15cm tall.

From Porvair Sciences Limited 7 Jan 2022

Novel delivery system for genome editing in vascular endothelial cells developed

The laboratory of Youyang Zhao developed a novel nanoparticle to deliver genome editing technology, such as CRISPR/Cas9, to endothelial cells, which line blood vessel walls.

7 Jan 2022

Study analyzes the role of individual soil microbes to predict climate change

Soil is a very complex ecosystem that is crucial to a healthy climate. It is one of the largest carbon repositories and home to billions of microorganisms.

7 Jan 2022

NRL scientists apply new methods to analyze cell behavior

Naval Research Laboratory researchers in the Chemistry Division apply their knowledge of biology in conjunction with materials to improve understanding of how cells and tissues organize and apply new methods to affect cell communication.

From United States Naval Research Laboratory 6 Jan 2022

New model system reveals how tiny bacteria from the environment have adapted to live inside humans

The microbes that live inside our mouths, collectively known as the oral microbiome, impact our overall health in many ways that are not yet fully understood.

4 Jan 2022

Researchers discover a crucial and exploitable vulnerability in diffuse large B cell lymphomas

Aggressive and relatively common lymphomas called diffuse large B cell lymphomas (DLBCLs) have a critical metabolic vulnerability that can be exploited to trick these cancers into starving themselves, according to a study from researchers at Weill Cornell Medicine and Cornell's Ithaca campus.

4 Jan 2022

New high-quality assay can be used in at-home tests for rapid COVID-19 screening

Researchers at the University of Illinois Chicago have designed a high-quality assay that can be used in at-home tests for rapid COVID-19 screening.

4 Jan 2022

Laboratory News and Research

Experts develop CRISPR-Cas9-mediated inheritance control in male mice

Study finds gene family that regulates tissue-specific DNA methylation patterns

Increasing the expression of a gene slows Alzheimer’s progression in mice

CSHL researchers spotlight the role of a previously little-known protein in leukemia

Scientists discover new Senp5S protein with crucial role in brain development

Researchers reveal molecular and cellular mechanisms that lead to tertiary lymphoid structures formation

High resolution single tube reader

Research explains how E4 peptide exerts antifibrotic effect and what makes it so effective

Neurons derived from human stem cells can predict the cardinal features of psychiatric illness

Study says plant microbiome influences health, survival, and fitness

Versatile method produces massive numbers of authentic human heart muscle cells

Omicron variant hampers the effectiveness of vaccines and monoclonal antibodies, study shows

CAR T cells produced in vivo using modified mRNA treat cardiac injury

Integrating Microplate Evaporators with Liquid Handling Robots

Novel delivery system for genome editing in vascular endothelial cells developed

Study analyzes the role of individual soil microbes to predict climate change

NRL scientists apply new methods to analyze cell behavior

New model system reveals how tiny bacteria from the environment have adapted to live inside humans

Researchers discover a crucial and exploitable vulnerability in diffuse large B cell lymphomas

New high-quality assay can be used in at-home tests for rapid COVID-19 screening

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