Anti Inflammatory News and Research

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Warped immune cell signaling during bile acid exposure may lead to Crohn’s disease

People with Crohn's disease are typically treated with powerful anti-inflammatory medications that act throughout their body, not just in their digestive tract, creating the potential for unintended, and often serious, side effects.

8 Apr 2021

Study reveals mechanism by which ibuprofen prevents RAC1B alternative splicing in colorectal cells

Oncotarget published "Ibuprofen disrupts a WNK1/GSK3β/SRPK1 protein complex required for expression of tumor-related splicing variant RAC1B in colorectal cells" which reported that although the molecular mechanism behind the antitumor properties of NSAIDs has been largely attributed to inhibition of cyclooxygenases , several studies have shown that the chemopreventive properties of ibuprofen also involve multiple COX-independent effects.

23 Mar 2021

Novel agonistic effect of polyphenol compound could treat amyloidosis, other metabolic disorders

Reportedly, Curcumin has several physiological activities, which include anti-inflammatory, anti-oxidation, anti-amyloid, and anti-cancer properties.

1 Mar 2021

Study may lead to alternative treatment for potentially addictive opioid pain killers

When two naturally occurring lipids are altered using a process called epoxidation, they are transformed into powerful agents that target numerous cannabinoid receptors in neurons, disrupting pathways that promote inflammation and pain.

11 Feb 2021

Study discovers new anti-inflammatory role for well-known blood clot protein

Flinders University researchers have discovered a new anti-inflammatory role for well-known blood clot protein fibrinogen, which could support targeted new treatments for kidney, heart and other common diseases.

2 Feb 2021

Researchers identify a new compound for creating a new class of diabetes drugs

A new study headed by the Ohio State University Wexner Medical Center and the College of Medicine has found a new compound that could form the base for creating a new class of diabetes drugs.

28 Jan 2021

TBI: Increased levels of immune cells promote inflammation that may worsen brain damage

Immediately after a traumatic brain injury and as long as one year later, there are increased levels of immune cells called ILCs in the brain promoting inflammation, which can worsen brain damage, scientists report.

27 Jan 2021

Non-steroidal anti-inflammatory drugs reduce antibody and inflammatory responses to COVID-19

According to a new study, non-steroidal anti-inflammatory drugs (NSAIDs) decreased both inflammatory and antibody responses to SARS-CoV-2 infection in mice.

26 Jan 2021

New model can help identify potential drug targets for ulcerative colitis

Scientists from the Lerner Research Institute at Cleveland Clinic have designed an innovative, patient-derived model of ulcerative colitis that will help scale up studies into new therapies for chronic inflammatory bowel disease.

12 Jan 2021

New fermented coffee and tea contain gut-friendly live probiotics

Good news for those who need a cuppa to start the day. Researchers from the National University of Singapore (NUS) have created new probiotic coffee and tea drinks that are packed with gut-friendly live probiotics.

From National University of Singapore (NUS) 12 Jan 2021

Main bioactive compound of ginger root counteracts autoimmune diseases in mice

Naturopathic medicine, or herbal medicine, is all the rage, especially among young people. But how much of this is supported by science?

7 Jan 2021

Gene expression database sheds light on pneumococcal infection

Researchers at the University of Maryland School of Medicine published one of the most comprehensive analyses of how genes get expressed during infection (known as a transcriptome).

16 Dec 2020

Disturbances in the gut microbiome may explain major depressive disorder

Researchers have successfully detected three bacteriophages, 50 fecal metabolites, 47 bacterial species that were considerably more or less abundant in patients with major depressive disorder (MDD) when compared to healthy controls. The study involved 311 individuals.

4 Dec 2020

Plant-inspired alkaloids could prevent and treat bacteria infections in rice, kiwi, and citrus

Plants get bacterial infections, just as humans do. When food crops and trees are infected, their yield and quality can suffer. Although some compounds have been developed to protect plants, few of them work on a wide variety of crops, and bacteria are developing resistance.

3 Dec 2020

Anti Inflammatory News and Research

Warped immune cell signaling during bile acid exposure may lead to Crohn’s disease

Study reveals mechanism by which ibuprofen prevents RAC1B alternative splicing in colorectal cells

Novel agonistic effect of polyphenol compound could treat amyloidosis, other metabolic disorders

Study may lead to alternative treatment for potentially addictive opioid pain killers

Study discovers new anti-inflammatory role for well-known blood clot protein

Researchers identify a new compound for creating a new class of diabetes drugs

TBI: Increased levels of immune cells promote inflammation that may worsen brain damage

Non-steroidal anti-inflammatory drugs reduce antibody and inflammatory responses to COVID-19

New model can help identify potential drug targets for ulcerative colitis

New fermented coffee and tea contain gut-friendly live probiotics

Main bioactive compound of ginger root counteracts autoimmune diseases in mice

Gene expression database sheds light on pneumococcal infection

Disturbances in the gut microbiome may explain major depressive disorder

Plant-inspired alkaloids could prevent and treat bacteria infections in rice, kiwi, and citrus

Chemical compounds in foods can inhibit a key SARS-Cov-2 enzyme

Study: Painkillers interfere with auxin flow essential for developmental processes in plants

Researchers identify chemical compounds that could block key enzyme in SARS-CoV-2

UofL researcher finds less toxic way to deliver medicines

Study finds that cannabidiol induces the expression of heme oxygenase 1 in skin cells

Study confirms correlation between gut microbiota and Alzheimer's disease

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