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Large-Bodied Kangaroo Weren’t Only Specialized in Endurance-Hopping, Shows Study

Extinct kangaroos used alternative methods to their famous hop according to comprehensive analysis from University of Bristol and the University of Uppsala scientists.

14 Jun 2023

Key Atomic Structures of the Actin Filament Revealed Through Cryo-EM

Actin filaments -; protein structures critical to living movement from single cells to animals -; have long been known to have polarity associated with their physical characteristics, with growing "barbed" and shrinking "pointed" ends.

9 Jun 2023

Scientists Discover a New Step in the Differentiation of Precursor Cells Into Mature Basophils

Big changes often happen in small steps, and it's not always easy to see how we get from point A to point B.

8 Jun 2023

Newly Identified Cellular Mechanism Enhances Photosynthesis in Marine Phytoplankton

Take a deep breath. Now take nine more. According to new research, the amount of oxygen in one of those 10 breaths was made possible thanks to a newly identified cellular mechanism that promotes photosynthesis in marine phytoplankton.

1 Jun 2023

Paleontologists Unearth the Largest-Ever Gomphothere in Florida

About five and a half million years ago, several gomphotheres -; extinct relatives of elephants -; died in or near a river in North Florida.

1 Jun 2023

Ex Vivo Expansion of HSCs Using a Novel Culture System

Hematopoietic stem cells (HSCs) are immature blood cells found in the bone marrow that can be stimulated to develop into any type of blood cell.

25 May 2023

African Spiny Mice Produce the Same Structures as Armadillos Beneath Their Tail Skin

Mammals are a bit odd when it comes to bones. Rather than the bony plates and scales of crocodiles, turtles, lizards, dinosaurs and fish, mammals long ago traded in their ancestral suit of armor for a layer of insulating hair.

25 May 2023

Identifying Drugs to Put the Brakes On Accelerated Aging From HIV Infection, Treatment

Antiretroviral cocktails can make human immunodeficiency virus, or HIV, undetectable and untransmittable, but both the virus and its treatment can also accelerate aging of bone and muscle.

24 May 2023

Research Uncovers the Biology Underpinning a Rare Genetic Mutation Linked to Painlessness

The biology underpinning a rare genetic mutation that allows its carrier to live virtually pain-free, heal more rapidly and experience reduced anxiety and fear, has been uncovered by new research from UCL.

24 May 2023

Scientists Engineer the First CRISPR-Based Drug Candidate to Directly Target E. Coli

Many people have experienced infections from E. coli, which are primarily seen as inconvenient and unpleasant.

10 May 2023

STING-seq Discovers Causal Variants and Genetic Mechanisms for Blood Cell Traits

A major challenge in human genetics is understanding which parts of the genome drive specific traits or contribute to disease risk. This challenge is even greater for genetic variants found in the 98% of the genome that does not encode proteins.

5 May 2023

Immune Evasion Mechanism of TNBC Cells Discovered

Freiburg researchers discover a mechanism by which cancer cells escape the immune system.

5 May 2023

New CAR T Strategy Offers a Dual-Targeting Mechanism to Fight Bone Metastatic Prostate Cancer

Prostate cancer frequently metastasizes to the bone and is incurable. Moffitt Cancer Center researchers are working to identify new treatment options for this subset of patients.

4 May 2023

Inhibiting a Tiny RNA Could Help Improve Immune, Bone, and Muscle Health With Age

Inhibiting a tiny RNA whose levels significantly increase with age, along with problems like weaker bones and sagging muscles, may be a way to keep our bodies more youthful and healthy, scientists say.

3 May 2023

New Bio-Inspired Molecules can Enhance Bone Regeneration in Mice

People's ability to regenerate bones declines with age and is further decreased by diseases such as osteoporosis.

2 May 2023

The Pivotal Role of Combinatorial CRISPR Gene Editing in the Elimination of HIV-1 Infection

Recent research from Temple University’s Lewis Katz School of Medicine and the University of Nebraska Medical Center demonstrates that gene-editing therapy aimed at two targets - HIV-1, the virus that causes AIDS, and CCR5, the co-receptor that aids the virus getting into cells—can effectively eliminate HIV infection.

2 May 2023

High-Throughput Screening of Existing Drugs to Fight Multiple Myeloma More Effectively

Multiple myeloma is a rare blood cancer caused by the uncontrolled multiplication of abnormal plasma cells.

28 Apr 2023

Antibacterial Biologic Agent Effective Against Staphylococcus Aureus Infections in Early Tests

Researchers at NYU Grossman School of Medicine and Janssen Biotech, Inc. have shown in early tests that a bioengineered drug candidate can counter infection with Staphylococcus aureus – a bacterial species widely resistant to antibiotics and a major cause of death in hospitalized patients.

25 Apr 2023

CloneTracer Reveals a Differentiation Landscape of Acute Myeloid Leukemia

Researchers have developed a new method to distinguish between cancerous and healthy stem cells and progenitor cells from samples of patients with acute myeloid leukemia (AML), a disease driven by malignant blood stem cells that have historically been difficult to identify.