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New Approach Aims to Enhance CRISPR Safety and Precision

CRISPR is a revolutionary tool that allows scientists to precisely modify the genome and gene expression of cells in any organism.

8 Oct 2024

How Comamonas Bacteria Transform Plastic Waste into Food

Researchers have long observed that a common family of environmental bacteria, Comamonadacae, grow on plastics littered throughout urban rivers and wastewater systems.

7 Oct 2024

Microbial Enzyme From Sewage Sludge Offers Hope for Plastic Waste Reduction

Plastic pollution is everywhere, and a good amount of it is composed of polyethylene terephthalate. This polymer is used to make bottles, containers and even clothing.

4 Oct 2024

Hydrogen Sulfide Plays a Crucial Role in Bacterial Survival

Two crucial biological processes that support the growth of bacteria, particularly pathogenic bacteria like Escherichia coli, are antibiotic resistance and the oxidative stress response.

30 Sep 2024

Mosquitoes use Salivary Protein to Aid Malaria Parasite Transmission

The study identifies AgApyrase as a key protein in mosquito saliva, enhancing Plasmodium transmission by regulating blood clot breakdown and immune response.

30 Sep 2024

Macrophage-Specific MAFB Deficiency Leads to Poor Prognosis in Acute Kidney Injury

Acute kidney injury (AKI) is associated with a poor prognosis, and no effective treatment has been established to date. Understanding the mechanisms that prevent the progression of AKI is crucial. In AKI, immune cells known as macrophages produce lipid mediators (LMs), which are lipids with significant physiological activity and play a pivotal role in promoting and suppressing inflammation. Thus, elucidating their function is of paramount importance.

30 Sep 2024

Neutron Scattering Reveals Enzyme Secrets

Scientists have uncovered amazing information about the role of an enzyme that could assist in the development of drugs for aggressive cancers in just two neutron experiments.

25 Sep 2024

New Method Detects Peroxymonocarbonate and Its Role in Cellular Responses

High levels of carbon dioxide (CO2) in the atmosphere can alter not only the climate of our planet but also the functioning of our cells.

24 Sep 2024

AI-Driven Insights into Lasso Peptide Biosynthesis

Lasso peptides are natural products made by bacteria. Their unusual lasso shape endows them with remarkable stability, protecting them from extreme conditions. In a new study, published in Nature Chemical Biology, researchers have constructed and tested models for how these peptides are made and demonstrated how this information might be used to advance lasso peptide-based drugs into the clinic.

23 Sep 2024

Sodium Transport Found to Play a Surprising Role in Mitochondrial Energy Production

The GENOXPHOS (Functional Genetics of the Oxidative Phosphorylation System) group at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has discovered a crucial role of sodium in the generation of cellular energy.

20 Sep 2024

Low Extracellular Sodium Concentrations Can Suppress mRNA Expression in Brain Cells

Brain and mental problems can result from chronic hyponatremia, a disorder marked by low blood salt levels.

19 Sep 2024

PKN Inhibition Reduces Cardiac Fibrosis and Improves Heart Function

The number of people suffering from heart failure is rising quickly as society ages. Heart failure progression is linked to fibrosis, or the overgrowth of fibrotic tissue in the heart.

16 Sep 2024

Potassium Isotope Ratios: A Potential Biomarker for Early Alzheimer's Disease Diagnosis

Potassium isotope ratios in serum show promise as biomarkers for Alzheimer's disease, revealing significant differences between patients and healthy controls.

16 Sep 2024

Automated DNA Separation for Sexual Assault Cases: A Breakthrough in On-Site Forensic Analysis

This study presents a digital microfluidics approach for rapid DNA extraction from sexual assault samples, significantly improving forensic analysis efficiency.

11 Sep 2024

CRISPR/Cas System Revolutionizes Tumor Variant and Biomarker Detection

The CRISPR-Cas system is transforming tumor biomarker detection, enabling ultra-sensitive diagnostics and improving accuracy in cancer detection and monitoring.

4 Sep 2024

The Molecular Process That Causes MS and Autoimmune Diseases

A human immune system suppressor known as “regulatory T cells” was first identified more than 20 years ago by a research team working in the lab of Yale researcher David Hafler, who was at Harvard at the time.

29 Aug 2024

Bifidobacterium in Maternal Gut Found to Alter Fetal Brain Growth

Bifidobacterium breve supplementation in pregnant mice alters fetal brain metabolism, highlighting its role in enhancing gestational health and development.

29 Aug 2024

The Influence of 'Silent' Mutations on Genetic Disorders

Genetic disorders -; like cystic fibrosis and Huntington's disease -; are considered incurable, with gene mutations occurring in essentially every cell of the body.

29 Aug 2024

Cryo-EM Study Sheds Light on HSV Drug Resistance Mechanisms Through Protein Movement

All organisms -; from fungi to mammals -; have the capacity to evolve and adapt to their environments. But viruses are master shapeshifters with an ability to mutate greater than any other organism. As a result, they can evade treatments or acquire resistance to once-effective antiviral medications.

28 Aug 2024

Unraveling the Molecular Mechanism Behind Neocapritermes taracua's Explosive Defense

Researchers from the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, in cooperation with colleagues from the Faculty of Tropical AgriScience of the Czech University of Life Sciences in Prague, are unraveling the mysteries of the life of termites.

28 Aug 2024

Enzyme News and Research

New Approach Aims to Enhance CRISPR Safety and Precision

How Comamonas Bacteria Transform Plastic Waste into Food

Microbial Enzyme From Sewage Sludge Offers Hope for Plastic Waste Reduction

Hydrogen Sulfide Plays a Crucial Role in Bacterial Survival

Mosquitoes use Salivary Protein to Aid Malaria Parasite Transmission

Macrophage-Specific MAFB Deficiency Leads to Poor Prognosis in Acute Kidney Injury

Neutron Scattering Reveals Enzyme Secrets

New Method Detects Peroxymonocarbonate and Its Role in Cellular Responses

AI-Driven Insights into Lasso Peptide Biosynthesis

Sodium Transport Found to Play a Surprising Role in Mitochondrial Energy Production

Low Extracellular Sodium Concentrations Can Suppress mRNA Expression in Brain Cells

PKN Inhibition Reduces Cardiac Fibrosis and Improves Heart Function

Potassium Isotope Ratios: A Potential Biomarker for Early Alzheimer's Disease Diagnosis

Automated DNA Separation for Sexual Assault Cases: A Breakthrough in On-Site Forensic Analysis

CRISPR/Cas System Revolutionizes Tumor Variant and Biomarker Detection

The Molecular Process That Causes MS and Autoimmune Diseases

Bifidobacterium in Maternal Gut Found to Alter Fetal Brain Growth

The Influence of 'Silent' Mutations on Genetic Disorders

Cryo-EM Study Sheds Light on HSV Drug Resistance Mechanisms Through Protein Movement

Unraveling the Molecular Mechanism Behind Neocapritermes taracua's Explosive Defense

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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