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Study reveals novel mechanism used by infectious bacteria to survive stressful situations

A new study led by researchers at University of Utah Health details a novel mechanism that infectious bacteria use to quickly adjust to environmental stress. The discovery could help explain why certain types of common infections-;such as urinary tract and bloodstream infections like sepsis- are hard to get rid of.

From The University of Utah 24 Mar 2022

Researchers create an atlas of cell types present in the white adipose tissue of humans, mice

Once considered to be inert, white adipose tissue is now recognized to be dynamic and to play an interactive role in a wide array of biological and metabolic processes.

21 Mar 2022

Study shows how the commensal oral microbiome can regulate alveolar bone health

It is becoming increasingly clear that the human microbiome – the collection of bacteria, viruses and fungi that live on and within us – significantly contributes to our health.

17 Feb 2022

Novel method can report specific immune cell types using only DNA from blood

Flow cytometry is a powerful and complex technology used to count, sort or measure characteristics of cells and to detect biomarkers.

10 Feb 2022

CRISPR-Cas9 likely to cause unforeseen genetic variations, researchers warn

Commonly referred to as “genetic scissors,” the CRISPR-Cas9 opens up new avenues for disease treatment—however, treatments must be effective.

4 Feb 2022

An Interview with The Million Veteran Program (MVP)

In this interview, we speak to Dr. Sumitra Muralidhar, the Program Director for VA’s Million Veteran Program (MVP) about the program and its aims for veterans.

28 Jan 2022

Largest nationwide study analyzes the link between food environment and dietary health

An estimated 19 million people in the U.S. live in so-called food deserts, which have lower access to healthy and nutritious food.

19 Jan 2022

Researchers map the cellular landscape in diabetic foot ulcers

Diabetic foot ulcerations – open sores or wounds that refuse to heal – are a devastating complication affecting more than 15 percent of people with diabetes and resulting in more than 70,000 lower extremity amputations per year in the United States alone.

11 Jan 2022

Research explains how E4 peptide exerts antifibrotic effect and what makes it so effective

A research team at the Medical University of South Carolina led by Carol Feghali-Bostwick, Ph.D., reports in the Journal of Clinical Investigation Insight that the E4 peptide reverses fibrosis, or scarring, in human and mouse tissues by activating an antifibrotic pathway that is common to all organ systems.

11 Jan 2022

New high-quality assay can be used in at-home tests for rapid COVID-19 screening

Researchers at the University of Illinois Chicago have designed a high-quality assay that can be used in at-home tests for rapid COVID-19 screening.

4 Jan 2022

Integration of digital and molecular data could enable individualized prevention of disease

Analyzing molecular characteristics and their variation during lifestyle changes, by combining digital tools, classical laboratory tests and new biomolecular measurements, could enable individualised prevention of disease.

3 Dec 2021

Study results facilitate construction of complex nanoscale computing agents

Scientists for the first time developed a nano computing agent that regulates the function of a specific protein involved in cell movement and cancer metastasis.

From Penn State University 19 Nov 2021

Genetic testing underutilized in patients with cardiomyopathies and arrhythmias, study says

Heart failure and arrhythmia conditions are often considered as separate disorders, but genetic testing suggests there is much more overlap of these disorders than previously appreciated.

11 Nov 2021

Study discusses outcomes of disclosing actionable genetic results to research participants

Over 120,000 patients have enrolled in the Mass General Brigham Biobank, offering access to crucial information related to their health history.

10 Nov 2021

Study finds several common genetic loci associated with dilated cardiomyopathy in U.S. veterans

A genome-wide association study has identified several common genetic loci (genetic locations) associated with dilated cardiomyopathy in U.S. veterans of European and African ancestry, according to preliminary research to be presented at the American Heart Association's Scientific Sessions 2021.

9 Nov 2021

Tackling pollution from ammonia emissions could reduce many premature deaths

Tackling pollution from the emission of nitrogen compounds, particularly ammonia, could reduce many of the 23.3 million years of life that were lost prematurely across the world in 2013 due to nitrogen-related air pollution, an international study led by Chinese scientists has discovered using a modeling framework, including the IIASA GAINS model.

5 Nov 2021

Blood metabolite levels altered by coffee consumption and may affect chronic kidney disease risk

Food and beverages may have important effects on kidney health, but the potential biological mechanisms involved are often unclear.

5 Nov 2021

Correction of immune system's faulty timing may offer a new strategy to prevent severe COVID-19

Once an infection is under control, the body normally uses a biochemical messenger known as TGFβ to downgrade its immune response.

27 Oct 2021

Study identifies a novel role for regulatory protein Bach1 in Parkinson's disease

Parkinson's disease (PD) is the most common neurodegenerative movement disorder, afflicting more than 10 million people worldwide and more than one million Americans. While there is no cure for PD, current therapies focus on treating motor symptoms and fail to reverse, or even address, the underlying neurological damage.

26 Oct 2021

Genetic biomarker test could help personalize therapy for men with high-risk prostate cancer

A new meta-analysis finds that a genetic biomarker test accurately predicts how men with high-risk prostate cancer will respond to treatment with radiation and hormone therapy.