Parkinson's Disease News and Research

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Parkinson's disease is a brain disorder. It occurs when certain nerve cells (neurons) in a part of the brain called the substantia nigra die or become impaired. When approximately 80 percent of neurons are damaged, the symptoms of Parkinson's disease appear. Parkinson's disease affects 1 in 100 people over the age of 60, with the average age of onset being 60 years. The risk of developing Parkinson's disease increases with age. In the United States, it is estimated that 60,000 new cases of Parkinson's disease are diagnosed each year, with 1.5 million Americans currently living with the disease.

Stem cells can repair parkinson's-damaged circuits in mouse brains

The mature brain is infamously bad at repairing itself following damage like that caused by trauma or strokes, or from degenerative diseases like Parkinson's.

28 Sep 2020

Researchers identify new therapeutic target for spinocerebellar ataxia

Scientists have created an animal model that simulates cerebellar neurodegeneration and motor dysfunction.

25 Sep 2020

Biomarker for diagnosis of neurodegenerative diseases identified in the eye

A new study led by Boston Medical Center researchers indicates a well-known biomarker that serves as a marker for earlier diagnosis of neurodegenerative diseases is now detectable in the eye.

24 Sep 2020

Star-shaped brain cells are essential for blood-brain barrier health, shows study

Hard skulls help protect our brains from physical injuries.In addition to a tough outer shell, brains have internal defenses, including a powerful shield called the blood-brain barrier that defends brain cells from substances in the bloodstream that are toxic and dangerous to nerve cells. If the blood-brain barrier is breached, then health problems arise.

22 Sep 2020

Smart drug delivery system may help treat spinal cord injuries and other neurological disorders

A Rutgers-led team has created a smart drug delivery system that reduces inflammation in damaged nervous tissues and may help treat spinal cord injuries and other neurological disorders.

From Rutgers University 18 Sep 2020

Researchers identify the cause for Parkinson's disease and potential treatments

In a seven-year research effort, an international team of scientists has clarified the cause for certain genetic forms of Parkinson's disease, and has identified potential pharmacological treatments.

14 Sep 2020

Researchers explore link between uncontrolled inflammation and brain's immune cells

Inspired by the need for new and better therapies for neurodegenerative diseases, such as Parkinson's disease and Alzheimer's disease, Rutgers University researchers are exploring the link between uncontrolled inflammation within the brain and the brain's immune cells, known as microglia.

9 Sep 2020

Study highlights the role of brain astrocyte cells in Parkinson's disease pathology

A new study using induced pluripotent stem cell (iPSC) technology links astrocyte dysfunction to Parkinson's disease (PD) pathology.

9 Sep 2020

Researchers perform massive and detailed cellular energy audit

TK Adenosine triphosphate, or ATP, is the cellular energy currency that is as valuable to the human body as the dollar is to the US economy. Too high or too low levels of ATP in some cell types have been linked to a variety of diseases.

31 Aug 2020

Findings show new promise for using stem cells to treat enteric nervous system disorders

Scientists have made a breakthrough in understanding how the enteric nervous system forms, which could pave the way for new treatments for neurodegenerative diseases such as Parkinson's.

28 Aug 2020

Protective anti-prion antibodies found in humans

Antibodies targeting the normal PrP version of the prion protein have been found in humans selected at random with no history of any associated transmissible spongiform encephalopathies.

18 Aug 2020

Switching off 'master regulator' may offer neuroprotection from Parkinson's-related damage

Switching off a molecular "master regulator" may protect the brain from inflammatory damage and neurodegeneration in Parkinson's disease, reports a study published today in Nature Neuroscience.

18 Aug 2020

Mathematical model shows how stability inherently arises in the brain

Whether you are playing Go in a park amid chirping birds, a gentle breeze and kids playing catch nearby or you are playing in a den with a ticking clock on a bookcase and a purring cat on the sofa, if the game situation is identical and clear, your next move likely would be, too, regardless of those different conditions.

11 Aug 2020

Rutgers expert highlights the effects of climate change on allergies, autoimmunity and the microbiome

Climate change and disruption of the ecosystem have the potential to profoundly impact the human body. Xue Ming, professor of neurology at Rutgers New Jersey Medical School, who recently published a paper in the International Journal of Environmental Research and Public Health on the effects of climate change on allergies, autoimmunity and the microbiome -- the beneficial microorganisms that live on and inside the human body -- discusses how the delicate balance of the environment affects conditions such as allergies, autism and immune disorders.

6 Aug 2020

Machine learning can increase effectiveness of drug repurposing for psychiatric disorders

Artificial intelligence can increase the effectiveness of drug repositioning or repurposing research, according to a study published in Translational Psychiatry.

4 Aug 2020

Research identifies how the gut communicates with spinal cord and brain

You're faced with a big decision so your second brain provides what's normally referred to as 'gut instinct', but how did this sensation reach you before it was too late?

27 Jul 2020

Study sheds light on the role of white blood cells in the developing brain

Whether white blood cells can be found in the brain has been controversial, and what they might be doing used to be complete mystery.

23 Jul 2020

Study: High levels of iron in the blood can prevent age-related damage

Genes linked to ageing that could help explain why some people age at different rates to others has been identified by scientists.

17 Jul 2020

Study: PINK1 and Parkin work together to induce selective autophagy

Researchers at TMIMS have revealed that PINK1 (a serine/threonine kinase) and Parkin (a ubiquitin ligating enzyme: E3) work together to ubiquitylate the outer membrane proteins of damaged mitochondria to induce selective autophagy called mitophagy.

10 Jul 2020

Salmonella biofilm protein can cause autoimmunity and arthritis in animals

Scientists from the Vaccine and Infectious Disease Organization-International Vaccine Centre at the University of Saskatchewan and Temple University have demonstrated that a Salmonella biofilm protein can cause autoimmune responses and arthritis in animals.