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Study identifies the role of three key molecules in the immune defense against porcine reproductive and respiratory syndrome virus

Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) is one of the most deadly diseases in the swine industry.

4 Mar 2022

Researchers find an epigenetic adaptation showing resistance to targeted therapy in T cell leukemia

Although gene mutations can result in drug resistance, scientists in the Perelman School of Medicine at the University of Pennsylvania have found a vital, non-genetic version that could also boost resistance to targeted treatment in T cell leukemia, which is a kind of blood cell cancer.

3 Mar 2022

UH researcher secures $2 million to develop drugs for formerly undruggable cancer targets

With a $2 million recruitment grant from the Cancer Prevention and Research Institute of Texas, a University of Houston researcher is setting up a lab to develop drugs that will work on traditionally undruggable targets in cancer.

3 Mar 2022

Recent study reveals the code involved in human gene regulation

The logic that handles gene regulation in human cells has been discovered by a team of researchers at the University of Helsinki.

24 Feb 2022

Dresden researchers explain how liquid-like protein droplets read DNA regions

A single cell forms the basis of life. As an organism grows, dividing cells specialize to produce the many tissues and organs that make up the adult body.

From The Max Planck Institute 14 Feb 2022

Study shows how root symbiosis with fungi is driven by the plant’s phosphate status

Phosphorus is one of the most important nutrients for plants. Among other functions, it is needed to create substances for the plant’s immune system, for the healthy development of seeds and for root growth.

9 Feb 2022

Identification of a bivalent histone-mark switch essential for angiogenesis

Defying conventional epigenomic wisdom, the non-conventional polycomb (PRC)1 variant paradoxically overwhelms the conventional PRC-mediated gene silencing in activated endothelial cells.

9 Feb 2022

Researchers make new advances in connecting the evolution of pregnancy and cancer metastasis

Researchers from UConn Heath and Yale University have made new advances connecting the evolution of pregnancy and cancer metastasis.

8 Feb 2022

Cell communication determines the specialization of individual cells during development, study shows

In just a few weeks a completely new organism develops from a fertilized egg cell. The real miracle is that a bunch of identical stem cells turns into completely different, specialized cell types.

From The Max Planck Institute 9 Nov 2021

Researchers reveal the dual function of a zinc finger protein

Human genome mapping was followed by rapid scientific advancements that showed the astonishingly complex world of genetics.

29 Oct 2021

Researchers identify a gene that could help improve flavor and shelf-life of tomatoes

Buying tomatoes and other fruits in the grocery store is always a gamble because, however good they look, they are often firm but lack flavor.

26 Oct 2021

Researchers uncover the ancestral role of key transcription factors in plants

Scientists from Japan have identified a major piece of the puzzle of plant evolution earlier ignored by plant researchers.

1 Oct 2021

Study employs machine learning to predict outcomes in agriculture

Recent research emphasizes that machine learning can identify “genes of importance” that support crops to grow with reduced fertilizer.

From New York University (NYU) 28 Sep 2021

How does the KLF4 transcription factor influence gene expression?

Scientists have led a research group to identify a mechanism using which transcription factor KLF4 can influence gene expression.

24 Sep 2021

Genetic and epigenetic origin of pediatric liver cancer uncovered

Researchers at Hiroshima University have analyzed the molecular findings of almost 160 pediatric liver cancer cases and discovered molecular markers that should help to understand and treat the considerable variation in prognoses.

22 Sep 2021

Researchers seek to point a way toward a unified theory for DNA folding

At more than 2 meters long, the human DNA molecule uses intricate folding patterns to fit into cells while locally unfolding to express genes. Such phenomena, however, are difficult to measure in experiments, and theoretical frameworks explaining them continue to be at odds with one another.

22 Sep 2021

Transcription Factors News and Research

Study identifies the role of three key molecules in the immune defense against porcine reproductive and respiratory syndrome virus

Researchers find an epigenetic adaptation showing resistance to targeted therapy in T cell leukemia

UH researcher secures $2 million to develop drugs for formerly undruggable cancer targets

Recent study reveals the code involved in human gene regulation

Dresden researchers explain how liquid-like protein droplets read DNA regions

Study shows how root symbiosis with fungi is driven by the plant’s phosphate status

Identification of a bivalent histone-mark switch essential for angiogenesis

Researchers make new advances in connecting the evolution of pregnancy and cancer metastasis

Cell communication determines the specialization of individual cells during development, study shows

Researchers reveal the dual function of a zinc finger protein

Researchers identify a gene that could help improve flavor and shelf-life of tomatoes

Researchers uncover the ancestral role of key transcription factors in plants

Study employs machine learning to predict outcomes in agriculture

How does the KLF4 transcription factor influence gene expression?

Genetic and epigenetic origin of pediatric liver cancer uncovered

Researchers seek to point a way toward a unified theory for DNA folding

Study reveals how the tumor suppressor gene plays a vital role in pediatric rhabdomyosarcoma

Researchers develop novel cell reprogramming strategy to slow down glioblastomas

Study uncovers mechanism where two transcription factors stabilize each other’s binding to DNA

Study imparts mechanistic understanding on early stages of human cancer

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