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A gene is a unit of heredity in a living organism. It normally resides on a stretch of DNA that codes for a type of protein or for an RNA chain that has a function in the organism. All living things depend on genes, as they specify all proteins and functional RNA chains.

RNA Modification in Driving Pancreatic Cancer Growth

RNA molecules can undergo chemical changes like m6A, which can have a significant influence on gene expression and affect several aspects of cancer development and progression

7 Aug 2023

New Insights Into How T Cells Become Exhausted in Cancer

Immune system T cells that should be able to kill cancer cells become dysfunctional or "exhausted" within hours of encountering a tumor, according to a study reported Aug. 3 in Nature Immunology.

7 Aug 2023

Elephants may Hold Secrets to Long Life

Indiana University researcher Daniella Chusyd is studying human aging in an unlikely way: through elephants.

7 Aug 2023

Environmental Factors Linked With AD Children Aged Between 15 – 35 Months Living in Rural Areas

Children raised in rural environments who spend a lot of time outdoors with some exposure to animals grow to have better regulated immune systems than children living in urban environments, a new study has found.

4 Aug 2023

Determining a Network of Cellular Programs Controlling Human Cancers

A Ludwig Cancer Research study has identified a pair of genes whose expression by a type of immune cell within tumors is predictive of outcomes for cancer patients and is linked to a vast network of gene expression programs, engaged by multiple cell types in the tumor microenvironment, that control human cancers.

4 Aug 2023

Study Shows How Sensory Neurons Control Gastrointestinal Tracts

Gastrointestinal and digestive issues impact roughly 3 million people across the United States alone, and that number is growing.

4 Aug 2023

Mothers Who Eat Herbs in Early Pregnancy Can Protect Their Grandchildren’s Brains, Finds Study

Mothers who eat apples and herbs in early pregnancy could be protecting the brain health of their children and grandchildren, a Monash University study using genetic models has found.

4 Aug 2023

Discovering Age and Sex-Specific Obesity Genes in the Genome

Right from impacting how the human body stores fat to how the brain regulates appetite, hundreds of genes, together with environmental factors, jointly identify weight and body size.

3 Aug 2023

New Mechanism of Cannibalism Discovered in Bacillus velezensis SQR9

When considering a bacterial population as a multicellular community, it is imperative to understand the inherent roles of maintaining homeostasis and viability in response to environmental factors.

3 Aug 2023

How the Tropical Red Swamp Crayfish Successfully Invaded the Cold Regions of Japan

Researchers from Japan have identified the molecular mechanisms that allow the red swamp crayfish to develop cold tolerance and, thus, colonize cold regions.

3 Aug 2023

Potential Strategies for Slowing Cognitive Deterioration in Age-Associated Neurodegenerative Conditions

As we age, our bodies undergo various changes that can impact our overall health and make us more susceptible to diseases.

3 Aug 2023

Single-Cell Sequencing Finds New Cell Types in the Visual Systems of Flies

Researchers from New York University have created a method that discovers and labels neurons throughout development, which has allowed them to identify novel cell types in the visual system of flies.

1 Aug 2023

Researchers Discover New Way to Attack Fungal Infections

Researchers at the RIKEN Center for Sustainable Research Science (CSRS) and the University of Toronto have discovered a new way to attack fungal infections.

1 Aug 2023

New Insights Into Lactate Transporters and Their Therapeutic Potential

Researchers from the Giulio Superti-Furga Lab at CeMM, the Austrian Academy of Sciences’ Research Center for Molecular Medicine, have developed a new technique for identifying specific inhibitors of a lactate transporter linked to cancer and other diseases.

31 Jul 2023

Study Provides New Insight Into the Evolutionary History of Gorillas

An international research study led by the University of Vienna (Austria) and the Institute of Evolutionary Biology (IBE) in Barcelona (Spain), recently published in the journal Nature Ecology and Evolution, provides a better insight into the evolutionary history of gorillas.

31 Jul 2023

New Gene Editing Technique Reduces Chalkiness in Rice

As global temperatures continue to rise, maintaining the quality and yield of crops adapted to lower temperatures will increasingly become a challenge.

31 Jul 2023

Coral Researchers Warn of Risks Associated with Selective Adaptation

Resilient corals, often referred to as 'super corals', have recently been seen as potential saviors in the face of climate change and its detrimental effects on coral reefs.

31 Jul 2023

Integrating Ultrasound with Genetics to Precisely Modify Neurons in the Brain

Researchers have developed methods to study and manipulate areas of the brain, though many of those methods are restricted by the limited depth that light can reach within the brain. A multidisciplinary team at Washington University in St. Louis plans to overcome that limitation by integrating ultrasound with genetics to precisely modify neurons in the brain.

28 Jul 2023

Analyzing DNA Damage-Induced NF-κB Targeted by Novel Small Molecule Inhibitors

Chemotherapy and radiotherapy aim to destroy cancer cells by inducing DNA double-strand breaks – damage that, once inflicted, usually causes the cells to die. But damage to a cell's genetic material also activates a signaling pathway called IKK/NF-κB that helps prevent cell death, thus limiting the success of these treatments in patients.

28 Jul 2023

New Proof-of-Concept Model for Delivering Gene Editing Tools to Treat Blood Disorders

In a step forward in the development of genetic medicines, researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have developed a proof-of-concept model for delivering gene editing tools to treat blood disorders, allowing for the modification of diseased blood cells directly within the body.

28 Jul 2023