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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Study may point to new therapeutic options for COVID-19

Contrary to what has been generally assumed so far, a severe course of COVID-19 does not solely result in a strong immune reaction - rather, the immune response is caught in a continuous loop of activation and inhibition.

7 Aug 2020

Study: Amyloid-beta alters cholesterol biosynthesis in early stages of Alzheimer’s

Korea Brain Research Institute (headed by Suh Pann-ghill) announced on July 24 the discovery that an increase in amyloid-beta in the brain alters cholesterol biosynthesis, which was found by Dr. Cheon Mookyung of KBRI through RNA-seq analysis data (omics) using AI.

7 Aug 2020

Deep Learning On Cell Signaling Networks Establishes AI For Single-Cell Biology

Computer systems that emulate key aspects of human problem solving are commonly referred to as AI. This field has seen massive progress over the last years.

6 Aug 2020

New UK supply contract for COVID-19 sample collection kits

EKF Diagnostics Holdings plc, the AIM listed point-of-care business, announces that it has received an initial order worth £3 m from a partner from the private sector to supply PrimeStore MTM, a novel patented sample collection device, to be used in a COVID-19 testing programme for UK staff.

From EKF Diagnostics 5 Aug 2020

NIH clinical study to evaluate potential new therapeutics for mild, moderate COVID-19

A Phase 2 clinical trial will evaluate the safety and efficacy of potential new therapeutics for COVID-19, including an investigational therapeutic based on synthetic monoclonal antibodies (mAbs) to treat the disease.

5 Aug 2020

Scientists explore the role of epigenetic regulator factors in embryonic development

A research team at the Max Planck Institute for Molecular Genetics in Berlin has explored the role of factors in embryonic development that do not alter the sequence of DNA, but only epigenetically modify its "packaging".

5 Aug 2020

New method reveals the dynamics of cell development and gene activity

Studies on cellular dynamics are vital to interpret the development of cells and the progression of various diseases.

5 Aug 2020

Hudsonalpha researchers help elucidate functional elements of the genome

Although the Human Genome Project sequenced a nearly-complete human genome almost 20 years ago, only about two percent of the genes in the human genome have been extensively studied and identified as protein-coding genes. Proteins form the basis of living tissues and play a central role in biological processes.

3 Aug 2020

Detailed 3D structure provides a roadmap for tweaking CRISPR-Cas9–guided base editors

Within a mere eight years, CRISPR-Cas9 has become the go-to genome editor for both basic research and gene therapy.

31 Jul 2020

Study reveals new strategy to reduce tumor growth

According to a new study, tumors can escape the immune system by instructing immune cells to create immunosuppressive steroids.

31 Jul 2020

Understanding the structure of SARS-CoV-2 proteins may lead to novel drugs

COVID-19 is a disease caused by an RNA virus called SARS coronavirus 2 (SARS-CoV-2), that is, a virus that employs RNA to preserve its genetic data.

31 Jul 2020

New methods to regulate enzymes involved in SARS-CoV-2 virus infection

A research team from the HSE University has designed innovative methods for controlling the expression of TMPRSS2 and ACE2 enzymes.

30 Jul 2020

Multiomics analysis reveals multiple characteristics of HIV-1-producing cells in vivo

For eradication of HIV-1 infection, it is important to elucidate the detailed features and heterogeneity of HIV-1-infected cells in vivo.

29 Jul 2020

Movement of small RNAs underlies mobile RNA interference

Biologists have known for some time that RNA interference can silence genes in far-off cells. They suspected that a messenger substance “transmits” RNA interference.

29 Jul 2020

'Marie Kondo' enzyme helps fruit fly embryos to clean out maternal proteins

Researchers at the University of Colorado School of Medicine have discovered a protein in fruit fly embryos, dubbed Marie Kondo, that destroys maternal proteins.

29 Jul 2020

Study sheds new light on core regulatory networks that govern cell types in vertebrates

The FANTOM Consortium has shed new light into the main regulatory networks that govern the types of cells found in different vertebrate species.

29 Jul 2020

AI algorithm can identify patterns of mutations and prognosis from tumor images

Researchers at EMBL's European Bioinformatics Institute, the Wellcome Sanger Institute, Addenbrooke's Hospital in Cambridge, UK, and collaborators have developed an artificial intelligence algorithm that uses computer vision to analyse tissue samples from cancer patients.

28 Jul 2020