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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

A fine balance between maintaining immunity and longevity

As we age, the immune system gradually becomes impaired. One aspect of this impairment is chronic inflammation in the elderly, which means that the immune system is constantly active and sends out inflammatory substances.

13 Jul 2020

Study may provide a therapeutically safer strategy for gene editing

The CRISPR gene editing system is a robust tool specifically developed for the targeted editing of genomes. While this tool has considerable therapeutic potential, it is associated with improper editing of “off-target” sites.

13 Jul 2020

Single-nucleus RNA sequencing helps compare transcriptional responses to acute cocaine

The lab of Jeremy Day, Ph.D., at the University of Alabama at Birmingham, has used single-nucleus RNA sequencing approaches to compare transcriptional responses to acute cocaine in 16 unique cell populations from a portion of the brain called the nucleus accumbens, or NAc.

From University of Alabama 10 Jul 2020

Bioinformaticians reveal previously unknown features of genes involved in brain functioning

In a recent study of genes involved in brain functioning, their previously unknown features have been uncovered by bioinformaticians from the Moscow Institute of Physics and Technology and the Institute of Mathematical Problems of Biology, RAS. The findings are reported in PLOS One.

10 Jul 2020

New type of molecular editor can make precise changes in mitochondrial DNA

The genome in mitochondria -- the cell's energy-producing organelles -- is involved in disease and key biological functions, and the ability to precisely alter this DNA would allow scientists to learn more about the effects of these genes and mutations.

9 Jul 2020

Lessons from early embryo could increase the efficiency of cell reprogramming

Cell reprogramming provides an outstanding opportunity for the artificial generation of stem cells for regenerative medicine approaches in the clinic.

7 Jul 2020

Organoids reveal inflammatory processes that play a role in infectious diseases

Research is employing mini-organs to model the digestive tract in the laboratory setting. These supposed organoids shed light on the inflammatory processes.

6 Jul 2020

Novel technology significantly improves the quality of stem cells

For years, stem cells have continued to have excellent potential in regenerative medicine.

6 Jul 2020

Study highlights the role of hematopoietic immune cells in gene regulation

More often, the human body is viewed as a “machine” containing specialized components: immune cells protect against pathogens, organs contribute physiological functions, and soft tissue and bones give structure.

6 Jul 2020

Mineral-coated microparticles are better vehicles for promising mRNA-based therapy

University of Wisconsin-Madison researchers have developed a safer and more efficient way to deliver a promising new method for treating cancer and liver disorders and for vaccination -- including a COVID-19 vaccine from Moderna Therapeutics that has advanced to clinical trials with humans.

3 Jul 2020

Discovery of new step in brain cell mechanism could lead to new treatments for epilepsy

Researchers have identified a critical new step in how brain cells function in people with one of the most common forms of epilepsy.

2 Jul 2020

Scientists develop CRISPR-assisted method to detect RNA-binding proteins in living cells

While scientists still don't fully understand the diverse nature of RNA molecules, it is believed that the proteins binding to them, called RNA-binding proteins, are associated with many disease formation.

2 Jul 2020

Study reveals how and where cells suppress transcription across the whole genome

All life depends on a genome, which acts as an instruction manual for building all the products essential for development and survival. But knowing which of these individual instructions - or genes - need to be read, and when, is key for a properly functioning organism: so how does life get this right?

1 Jul 2020

Singapore researchers discover protein that drives cancer progression

Cancers arise when the genetic code of normal cells is altered, causing excessive growth. Researchers from the Cancer Science Institute of Singapore at the National University of Singapore have discovered a protein that drives the growth of cancers of the esophagus or liver by altering the genetic code in a novel way.

30 Jun 2020

Deep-learning-based computational models predict the activities of SpCas9 variants

Specific sequences of DNA are typically cut using CRISPR-Cas9 that has become one of the most effective and convenient biotechnology tools today.

29 Jun 2020

Genome study opens pathway toward sustainable edible seaweed

Since the 1980s, in seaweed farms dotted along the coastline of the subtropical islands of Okinawa, farmers have cultivated the edible brown alga.

26 Jun 2020

Newly designed vesicles can help deliver drugs

Researchers have produced spherical and hollow sacks called vesicles using RNA and protein.

24 Jun 2020

Antibody and RNA testing can help track SARS-CoV-2 virus

SARS-CoV-2 is usually tracked by two types of tests, reverse transcriptase PCR (rt-PCR) and antibody tests.

23 Jun 2020

Study shows how fish farming affects microbial communities, nitrate levels in pond ecosystems

Small-scale water bodies with areas less than 0.1 km2, such as natural ponds, constitute the quantitative bulk of global inland water bodies, and are very susceptible to human disturbances and environmental change. In agricultural regions of China, water quality in ponds ha

23 Jun 2020

Alzheimer's: New Gene May Drive Earliest Brain Changes

A newly discovered Alzheimer's gene may drive the first appearance of amyloid plaques in the brain, according to a study led by researchers.

23 Jun 2020

RNA News and Research

A fine balance between maintaining immunity and longevity

Study may provide a therapeutically safer strategy for gene editing

Single-nucleus RNA sequencing helps compare transcriptional responses to acute cocaine

Bioinformaticians reveal previously unknown features of genes involved in brain functioning

New type of molecular editor can make precise changes in mitochondrial DNA

Lessons from early embryo could increase the efficiency of cell reprogramming

Organoids reveal inflammatory processes that play a role in infectious diseases

Novel technology significantly improves the quality of stem cells

Study highlights the role of hematopoietic immune cells in gene regulation

Mineral-coated microparticles are better vehicles for promising mRNA-based therapy

Discovery of new step in brain cell mechanism could lead to new treatments for epilepsy

Scientists develop CRISPR-assisted method to detect RNA-binding proteins in living cells

Study reveals how and where cells suppress transcription across the whole genome

Singapore researchers discover protein that drives cancer progression

Deep-learning-based computational models predict the activities of SpCas9 variants

Genome study opens pathway toward sustainable edible seaweed

Newly designed vesicles can help deliver drugs

Antibody and RNA testing can help track SARS-CoV-2 virus

Study shows how fish farming affects microbial communities, nitrate levels in pond ecosystems

Alzheimer's: New Gene May Drive Earliest Brain Changes

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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