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New links found between CRISPR, p53 and other cancer genes that could prevent accumulation of mutated cells

A protein that protects cells from DNA damage, p53, is activated during gene editing using the CRISPR technique.

18 Nov 2021

Scientists use AI and evolutionary analysis to produce 3D models of eukaryotic protein interactions

UT Southwestern and University of Washington researchers led an international team that used artificial intelligence (AI) and evolutionary analysis to produce 3D models of eukaryotic protein interactions.

17 Nov 2021

Covid-19 vaccine-elicited immune cells persist six months after vaccination, study shows

A recent study by Johns Hopkins Medicine researchers provides evidence that CD4+ T lymphocytes — immune system cells also known as helper T cells — produced by people who received either of the two available messenger RNA (mRNA) vaccines for COVID-19 persist six months after vaccination at only slightly reduced levels from two weeks after vaccination and are at significantly higher levels than for those who are unvaccinated.

17 Nov 2021

Genomic changes in advanced tumors reveal interactions with treatment

A novel way to look at cancer treatment resistance offers the possibility for identifying genetic mechanisms involved and alternative treatment approaches.

17 Nov 2021

Diet has a much stronger impact on the inner workings of cells than drugs

A study comparing the impact of diet versus drugs on the inner workings of our cells has found nutrition has a much stronger impact.

17 Nov 2021

Study identifies new gene that promotes progression to type 1 diabetes

When the pro-inflammatory pair, a receptor called CCR2 and its ligand CCL-2, get together, it increases the risk of developing type 1 diabetes, scientists report.

17 Nov 2021

Novel therapy induces phagocytosis to treat bacterial pneumonia

Scientists from the National Institutes of Health recently found a therapy that targets host cells instead of bacterial cells in treating bacterial pneumonia.

17 Nov 2021

Researchers test a neoantigen-specific transgenic immune cell therapy for malignant gliomas

Doctors and scientists from the German Cancer Research Center (DKFZ) and from Heidelberg University's Medical Faculty Mannheim have successfully tested a neoantigen-specific transgenic immune cell therapy for malignant brain tumors for the first time using an experimental model in mice.

16 Nov 2021

Green tea catechins extend the lifespan of C. elegans

Aging-US published "Green tea catechins EGCG and ECG enhance the fitness and lifespan of Caenorhabditis elegans by complex I inhibition" which reported that green tea catechins are associated with a delay in aging.

15 Nov 2021

Research details how HIV-infected cells evade detection by the immune system

Scientists from the Wistar Institute revealed how major features on the surface of HIV-infected cells help the disease avoid detection by the immune system.

15 Nov 2021

Apoptosis of mesenchymal stromal cells benefits therapeutic function

Scientists recently identified the therapeutic benefits to patients receiving mesenchymal stromal cell (MSC) therapy.

15 Nov 2021

CRISPR screening identifies metabolic enzyme as new target for anti-inflammatory therapeutics

A metabolic enzyme that has been studied in cancer biology and is important for T cell function may offer a new target for anti-inflammatory therapeutics, Vanderbilt researchers have discovered.

12 Nov 2021

Using a new genetic technology to decipher intratumoral heterogeneity

Even within a single patient with cancer, there is a vast diversity of individual tumor cells, which display distinct behaviors related to growth, metastasis, and responses to chemotherapy.

12 Nov 2021

Genetic testing underutilized in patients with cardiomyopathies and arrhythmias, study says

Heart failure and arrhythmia conditions are often considered as separate disorders, but genetic testing suggests there is much more overlap of these disorders than previously appreciated.

11 Nov 2021

Grape consumption has a beneficial effect on gut bacteria and cholesterol metabolism

A new clinical study published in the scientific journal Nutrients found that consuming grapes significantly increased the diversity of bacteria in the gut which is considered essential to good health overall.

11 Nov 2021

Seasoning foods with herbs and spices may help improve heart health

Seasoning your food generously with herbs and spices isn't just a great way to make your meals tastier -; new research found it may have benefits for your heart's health, as well.

From Penn State University 11 Nov 2021

Avoiding the formation of false positive results during SARS-CoV-2 antigen testing

In light of frequent false positives, a team of Canadian researchers has shown that rapid antigen tests for SARS-CoV-2 work only when manufacturer instructions are followed.

11 Nov 2021

Gold nanoclusters could be the new weapon in the fight against bacterial antibiotic resistance

Tiny particles of gold could be the new weapon in the fight against bacterial antibiotic resistance, according to research just published.

10 Nov 2021

New model for early prediction of cancer patients' response to immunotherapy

Researchers have developed a model that could predict early on in treatment whether cancer patients will respond to immunotherapy, according to a report published today in eLife.

10 Nov 2021

Study discusses outcomes of disclosing actionable genetic results to research participants

Over 120,000 patients have enrolled in the Mass General Brigham Biobank, offering access to crucial information related to their health history.

10 Nov 2021

Clinical News and Research

New links found between CRISPR, p53 and other cancer genes that could prevent accumulation of mutated cells

Scientists use AI and evolutionary analysis to produce 3D models of eukaryotic protein interactions

Covid-19 vaccine-elicited immune cells persist six months after vaccination, study shows

Genomic changes in advanced tumors reveal interactions with treatment

Diet has a much stronger impact on the inner workings of cells than drugs

Study identifies new gene that promotes progression to type 1 diabetes

Novel therapy induces phagocytosis to treat bacterial pneumonia

Researchers test a neoantigen-specific transgenic immune cell therapy for malignant gliomas

Green tea catechins extend the lifespan of C. elegans

Research details how HIV-infected cells evade detection by the immune system

Apoptosis of mesenchymal stromal cells benefits therapeutic function

CRISPR screening identifies metabolic enzyme as new target for anti-inflammatory therapeutics

Using a new genetic technology to decipher intratumoral heterogeneity

Genetic testing underutilized in patients with cardiomyopathies and arrhythmias, study says

Grape consumption has a beneficial effect on gut bacteria and cholesterol metabolism

Seasoning foods with herbs and spices may help improve heart health

Avoiding the formation of false positive results during SARS-CoV-2 antigen testing

Gold nanoclusters could be the new weapon in the fight against bacterial antibiotic resistance

New model for early prediction of cancer patients' response to immunotherapy

Study discusses outcomes of disclosing actionable genetic results to research participants

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