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Genetically encoded sensor helps detect hallucinogenic substances

Researchers at the University of California, Davis, have created a genetically encoded sensor for detecting hallucinogenic substances.

From The University of California, Davis 29 Apr 2021

Increased expression of DUSP16 molecule leads to cancer chemoresistance

Chemotherapy is a drug treatment that uses powerful chemicals to kill fast-growing cancer cells in the body. It is a systemic treatment where drugs travel throughout the body and destroy cancer cells that have spread (metastasized) to parts of the body far away from the original (primary) tumour.

28 Apr 2021

Developing a portable tool to detect street drug ‘spice’

AZoLifeSciences speaks to researchers from the University of Bath about their latest research that led to the development of a device that can detect 'spice'.

From University of Bath 28 Apr 2021

New, altered form of prolactin receptor found to drive breast cancer

Prolactin is a hormone that has long been thought to play an important role in breast development and growth, as well as milk production during pregnancy.

27 Apr 2021

Therapy using artificial metalloenzymes helps reduce tumor growth, finds study

A new study has shown that it is viable to reduce tumor growth by a therapy that involves tagging cancer cells with various therapeutic molecules.

26 Apr 2021

Cell membranes can boost the production of protein-based vaccines

Synthetic biologists have cracked open a cellular membrane, identifying a new method to boost the production yields of protein-based vaccines by five times.

26 Apr 2021

New AI model predicts targets for previously unmapped T cells against coronavirus

A research team has created an AI technique that can bind immune cells to their targets and uncouple the types of white blood cells that identify SARS-CoV-2.

26 Apr 2021

Study sheds light on the ability of cannabidiol to reduce pain

It's been hailed as a wonder drug and it's certainly creating wonder profits. By some estimates, the Cannabidiol (or CBD) market could be worth $20 billion dollars by 2024. While users tout its effectiveness in pain relief, up until now there's been limited experimental human research on the actual effectiveness of the drug

26 Apr 2021

Macrophages perform necessary damage-control function following tissue injury

Cardiovascular disease, the most common cause of death, is the result of oxygen deprivation as blood perfusion to affected tissue is prevented. To halt the development of the disease and to promote healing, re-establishment of blood flow is crucial.

26 Apr 2021

National DNA Day 2021: An Interview with Professor George Church

In celebration of National DNA Day, AZoLifeSciences interviews renowned DNA expert Professor George Church about his life-long career in DNA research.

From Harvard Medical School 23 Apr 2021

Study reveals key lipid-binding protein that contributes to cancer

Researchers have discovered how a portion of a protein communicates with a cell’s membrane to control crucial intercellular communications.

21 Apr 2021

Study shows how tau aggregates promote Alzheimer’s disease

If looked deep into the brain of a patient with Alzheimer’s disease or those suffering from the most types of dementia or the concussion-associated syndrome, called chronic traumatic encephalopathy (CTE), there would be hairball-like tangles of a protein known as tau—a common suspected culprit.

20 Apr 2021

Novel method to activate and visualize protein channels that keep bacteria alive

Almost all bacteria rely on the same emergency valves--protein channels that pop open under pressure, releasing a deluge of cell contents.

15 Apr 2021

Novel test detects HIV reservoir in patients more accurately

An innovative test that determines the quality and quantity of inactive HIV viruses in the genes of HIV patients may ultimately give scientists a better idea of effective drugs.

14 Apr 2021

Study shows that neural stem cells age quickly

A research team has revealed that neural stem cells (NSCs)—that is, the stem cells of the nervous system—age quickly.

14 Apr 2021

Scientists engineer probiotic yeast to produce beta-carotene in the guts of mice

Researchers have genetically engineered a probiotic yeast to produce beta-carotene in the guts of laboratory mice. The advance demonstrates the utility of work the researchers have done to detail how a suite of genetic engineering tools can be used to modify the yeast.

13 Apr 2021

Researchers identify and test drug combination that exploits a weakness in small cell lung cancer

Researchers from the National Institutes of Health have identified and tested a drug combination that exploits a weakness in small cell lung cancer (SCLC), an aggressive, dangerous cancer.

13 Apr 2021

Exercise training may slow tumor growth for females with breast cancer

Exercise training may slow tumor growth and improve outcomes for females with breast cancer - especially those treated with immunotherapy drugs - by stimulating naturally occurring immune mechanisms, researchers at Massachusetts General Hospital (MGH) and Harvard Medical School (HMS) have found.

13 Apr 2021

New method can improve the drug testing process

When developing a new drug, the first question is, “does it work?” and the second question is, “is it harmful?”

9 Apr 2021

Study explains molecular mechanisms of drug resistance in Mycobacterium tuberculosis

A group of researchers from France, Germany, Belarus, Japan, and Russia and headed by a scientist from Skolkovo Institute of Science and Technology (Skoltech) has discovered how Mycobacterium tuberculosis survives in iron-deficient environments by using rubredoxin B (RubB)—a protein that belongs to the rubredoxin family and plays a significant role in adapting to varying environmental conditions.

9 Apr 2021