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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Researchers develop a reliable technique for assessing the role of lncRNAs

The discovery of a huge number of long non-protein coding RNAs, aka lncRNAs, in the mammalian genome was a major surprise of the recent large-scale genomics projects.

18 May 2020

Aging neurons build up DNA damage, study finds

MIT neuroscientists have discovered that an enzyme called HDAC1 is critical for repairing age-related DNA damage to genes involved in memory and other cognitive functions.

18 May 2020

Researchers discover group of genes with altered expression in autism

Autism has long been associated only with behavioral and environmental factors, but the role of genetics in its development is now increasingly evident. Some 100 genes have been found to play a role in autism spectrum disorder, and another thousand are being studied to the same end.

15 May 2020

Mouse model helps track organism’s development, cell by cell

Scientists at the Stem Cell Research program at Boston Children's Hospital and Dana-Farber Cancer Institute/Harvard Medical School have devised a mouse model that lets researchers track every cell in the body, from the embryonic stage until adulthood.

15 May 2020

Coronavirus attacking microRNA numbers reduce with age

A group of tiny RNA that should attack the virus causing COVID-19 when it tries to infect the body are diminished with age and chronic health problems, a decrease that likely helps explain why older individuals and those with preexisting medical conditions are vulnerable populations, investigators report.

14 May 2020

Study reveals proteins that sustain cancer cells

Scientists from the University of Copenhagen have identified two major functions of the protein known as RTEL1 during cell division, in a recently performed study.

14 May 2020

Single-cell gene expression studies can shed more light on disrupted genes

Scientists can gain a better understanding of the cellular roles of the disrupted gene by disturbing the expression of a specific gene and tracking how this change has an impact on the expression of other types of genes.

13 May 2020

The microbiome regulates our immune system's fitness

Working alongside colleagues in Mainz, Bern, Hannover and Bonn, researchers from Charité - Universitätsmedizin Berlin, the Berlin Institute of Health and the German Rheumatism Research Center Berlin were able to show how the microbiome helps to render the immune system capable of responding to pathogens.

13 May 2020

Study could help design better methods to create muscle cells from stem cells

A research team has created the world’s first roadmap of the development mechanism of human skeletal muscles, including the development of muscle stem cells.

12 May 2020

Determining effect of drugs in pancreatic islets through single-cell RNA-seq approach

Scientists have developed a technique to assess the impact of particular drugs in pancreatic tissues by using an advanced single-cell RNA sequencing approach.

12 May 2020

mTOR gene in GvHD patients regulates cell growth and cell survival

Mutations that occur in white blood cells can play a major role in abnormal immune profile following hematopoietic stem cell transplantation.

11 May 2020

Research provides new insight into how molecular machines are built in living cells

New findings about critical cellular structures have upended common assumptions about their formation and composition and provided new insight how molecular machines are built in living cells.

8 May 2020

Researchers discover new therapeutic targets for cancer, male infertility

Researchers analyzed 13,000 tumors, highlighting two formerly overlooked genes as promising new therapeutic targets for treating cancer.

7 May 2020

Geneticists Revealed New Potential Causes Of Female Infertility

Over the last six years, a group of geneticists has studied genes associated primarily with female hormone synthesis and ovarian follicle development.

7 May 2020

Geneticists can induce "stress memory" in plants

By manipulating the expression of one gene, geneticists can induce a form of "stress memory" in plants giving them the potential for more productive growth.

6 May 2020

Virus-specific antibodies are generated by many newly discharged COVID-19 patients

A majority of the recently discharged patients who have currently recovered from the COVID-19 infection create virus-specific T cells and antibodies.

6 May 2020

Different Kinds Of White Fat Are Important In Disease

Excess white fat causes obesity, which in turn can drive metabolic diseases that are growing at epidemic rates around the world.

5 May 2020

Faulty mRNA in gene expression may contribute to neurodegenerative disorders

Complex organisms experience growth, followed by the transcription of these genes into RNA, and subsequently the translation of that transcript into proteins.

4 May 2020