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New Advances in DEL Technology Facilitate Synthesis of Large, Complex Molecules

These days, remarkable new medical treatments are all the rage. One such treatment is personalized cancer therapy, which uses antibodies or immune cells that have been altered.

4 Sep 2024

Beta Cells Alone Can Maintain Glycemic Balance Without Other Pancreatic Cells

Our glycemic balance is based on the ability of the pancreatic beta cells to detect glucose and secrete insulin to maintain our blood sugar levels.

4 Sep 2024

Melbourne Researchers Achieve Breakthrough in Creating Human-Like Blood Stem Cells

Melbourne researchers have made a world first breakthrough into creating blood stem cells that closely resemble those in the human body.

3 Sep 2024

Microbiotica Secures Approvals to Begin Clinical Studies in EU and UK for New Microbiome Medicines

Microbiotica, a biopharma company developing a pipeline of oral precision microbiome medicines called live biotherapeutic products (LBPs), is pleased to announce that it has received regulatory approvals to initiate clinical studies for its first two programmes in advanced melanoma (MELODY-1) and ulcerative colitis (COMPOSER-1) in selected EU countries and the UK. Both studies are due to start shortly, with initial data readouts expected by the end of 2025.

30 Aug 2024

European Commission Approves Erdafitinib for Advanced Urothelial Carcinoma

Janssen-Cilag International NV, a Johnson & Johnson company, today announced that the European Commission (EC) has approved BALVERSA®▼(erdafitinib) as a once-daily oral monotherapy for the treatment of adult patients with unresectable or metastatic urothelial carcinoma (mUC), harbouring susceptible fibroblast growth factor receptor 3 (FGFR3) genetic alterations who have previously received at least one line of therapy containing a programmed death receptor-1 (PD-1) or programmed death-ligand 1 (PD-L1) inhibitor in the unresectable or metastatic treatment setting.

30 Aug 2024

RYBREVANT Receives EC Nod for Advanced Lung Cancer Treatment

Janssen-Cilag International NV, a Johnson & Johnson company, today announced that the European Commission (EC) has approved a Type II extension of indication for RYBREVANT®▼ (amivantamab) in combination with chemotherapy (carboplatin and pemetrexed), for the treatment of adults with advanced non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) Exon 19 deletions (ex19del) or Exon 21 L858R substitution (L858R) mutations, after failure of prior therapy including an EGFR tyrosine kinase inhibitor (TKI).

30 Aug 2024

Pan-Pathogen Deep Sequencing: A New Strategy in Combating Nosocomial Antimicrobial Resistant Bacterial Infections

Deep sequencing of bacterial cultures reveals insights into nosocomial infections and antimicrobial resistance, enhancing pathogen surveillance in hospitals.

30 Aug 2024

A Landmark Study Reveals the Widespread Existence of DNA i-Motifs

Innovative study of DNA's hidden structures may open up new approaches for treatment and diagnosis of diseases, including cancer.

30 Aug 2024

Bacterial Protein Utilizes DNA for Target Recognition and Plasmid Elimination

Scientists who have described in a new study the step-by-step details of a bacterial defense strategy see the mechanism as a promising platform for development of a new genome-editing method.

30 Aug 2024

Single-Cell RNA Sequencing Reveals Cellular Changes in Early Alzheimer's Disease

An analysis of more than 1.6 million brain cells from older adults has captured the cellular changes that occur in the early stages of Alzheimer's disease, potentially revealing new routes for preventing the most common cause of dementia in older individuals.

29 Aug 2024

New Study Reveals Antibiotic Mismanagement in Aged Care Facilities

There is an urgent need for more careful antibiotic management to protect older people living in residential aged care from the dangerous spread of antibiotic-resistant bacteria or 'superbugs', researchers from Flinders University and SAHMRI warn.

29 Aug 2024

Nutrient Deprivation Strategy Kills Breast Cancer Cells by Blocking Adaptive Pathways

Cancer cells have voracious appetites. And there are certain nutrients they can't live without. Scientists have long hoped they might stop tumors in their tracks by cutting off an essential part of cancer cells' diet. But these cells are crafty and often find a new way to get what they need. How? By reprogramming their metabolism and switching to backup food supplies.

29 Aug 2024

RNA Interference Drugs Offer Faster, More Effective Alternative to Traditional Drug Discovery

Alnylam's RNA interference platform accelerates drug discovery by targeting RNA transcripts, addressing complex diseases with innovative therapeutic strategies.

28 Aug 2024

Innovative Stem Cell Research Unveils Glial Cell Dynamics in Multiple Sclerosis

Researchers from The New York Stem Cell Foundation (NYSCF) Research Institute and Case Western Reserve University have discovered novel ways in which glia, by using the largest known collection of stem cell models from MS patients, essential brain support cells contribute to the disease.

27 Aug 2024

Clinical News and Research

New Advances in DEL Technology Facilitate Synthesis of Large, Complex Molecules

Beta Cells Alone Can Maintain Glycemic Balance Without Other Pancreatic Cells

Melbourne Researchers Achieve Breakthrough in Creating Human-Like Blood Stem Cells

Microbiotica Secures Approvals to Begin Clinical Studies in EU and UK for New Microbiome Medicines

European Commission Approves Erdafitinib for Advanced Urothelial Carcinoma

RYBREVANT Receives EC Nod for Advanced Lung Cancer Treatment

Pan-Pathogen Deep Sequencing: A New Strategy in Combating Nosocomial Antimicrobial Resistant Bacterial Infections

A Landmark Study Reveals the Widespread Existence of DNA i-Motifs

Bacterial Protein Utilizes DNA for Target Recognition and Plasmid Elimination

Single-Cell RNA Sequencing Reveals Cellular Changes in Early Alzheimer's Disease

New Study Reveals Antibiotic Mismanagement in Aged Care Facilities

Nutrient Deprivation Strategy Kills Breast Cancer Cells by Blocking Adaptive Pathways

RNA Interference Drugs Offer Faster, More Effective Alternative to Traditional Drug Discovery

Innovative Stem Cell Research Unveils Glial Cell Dynamics in Multiple Sclerosis

Nile Grass Rats Become New Model for CRISPR Genome Editing

Clinical Trials Supported by Genetics Show Higher Success Rates

Study Identifies Key Macrophage Subpopulations in MASH Progression and Regression

Mitochondrial DNA 'Jumps' to Chromosomes, Potentially Impacting Lifespan

Efficient and Reproducible BBB Modeling for Drug Development

Study Reveals Dual Role of Skin Proteins in Strength and Cell Signaling

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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