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Fungal Pathogen Behind Banana Wipeout Identified

The fungal pathogen Fusarium oxysporum f.sp. cubense (Foc) tropical race 4 (TR4) is the source of the disease Fusarium wilt of banana (FWB), which is threatening to functionally wipe out the bananas in the supermarket and consumed as breakfast.

19 Aug 2024

Advancing Cardiovascular Drug Discovery: Translational Framework Leverages Genetic and Proteomic Insights

A validated framework to translate these recent advances in genoproteomics into clinical applications in cardiovascular drug development.

19 Aug 2024

Two Genes Control Explosive Taste Bud Growth in Cavefish

Over thousands of years, cavefish evolved and lost their vision, earning the moniker "the blind cavefish," but some cavefish also developed an inordinate number of taste buds on the head and chin.

16 Aug 2024

New Approach for Targeted Genome Editing in Wild Populations

Researchers from Macquarie University and the California Institute of Technology have discovered a novel method that, when published in Nature Communications on August 13th, 2024, might make it easier and more controllable for scientists to modify the genetic composition of wild populations than when using gene drives.

14 Aug 2024

Study Reveals Mechanisms Behind Lineage Restriction in Cell Development

A team of researchers from multiple institutions including the University of Chicago and VectorBuilder, has made a significant breakthrough in the understanding of lineage restriction, a biological phenomenon foundational to multicellular lifeforms as it secures the functional identities of the myriad cell types in the body.

14 Aug 2024

New Breast Cell Atlas Enhances Understanding of Cancer Origins

Scientists at the Melvin and Bren Simon Comprehensive Cancer Center at Indiana University have finished the largest mapping of healthy breast cells to date.

13 Aug 2024

Novel Technique to Study Ubiquitination

Once human proteins are synthesized, they go through some chemical changes. These adjustments control their stability, functionality, and structure.

13 Aug 2024

Advancing Genome Visualization with CRISPR/Cas9 Technology in Live Cells

Understanding the spatiotemporal organization of the genome in the nucleus is crucial for advancing our knowledge of chromatin structure and its functional dynamics in both normal and diseased states.

13 Aug 2024

New AI Model Predicts Protein-DNA Binding Specificity with High Accuracy

A new artificial intelligence model developed by USC researchers and published in Nature Methods can predict how different proteins may bind to DNA with accuracy across different types of protein, a technological advance that promises to reduce the time required to develop new drugs and other medical treatments.

12 Aug 2024

Utah Scientists Begin New Project to Map Epigenetic Changes Across the Human Genome

The Human Genome Project changed everything. A map of the entire human sequence of DNA was the starting point for an enormous number of discoveries, from disease genes to how humans evolved.

12 Aug 2024

Discovery of Largest Protein Sheds Light on Toxin Production in Marine Algae

While seeking to unravel how marine algae create their chemically complex toxins, scientists at UC San Diego's Scripps Institution of Oceanography have discovered the largest protein yet identified in biology.

12 Aug 2024

Discovery of Free-Floating Genes in Bacteria Challenges Genetic Code Assumptions

Since the genetic code was first deciphered in the 1960s, our genes seemed like an open book. By reading and decoding our chromosomes as linear strings of letters, like sentences in a novel, we can identify the genes in our genome and learn why changes in a gene's code affect health.

12 Aug 2024

CRISPR-Cas: A Promising Tool For Combatting Antibiotic-Resistant Staphylococcus aureus

Using CRISPR-Cas systems in various studies to detect and treat Staphylococcus aureus.

12 Aug 2024

From CRISPR-Cas to Fanzor system: New frontiers in gene editing

The features of various CRISPR-Cas systems, including CRISPR-associated transposons (CASTs) and the eukaryotic equivalent of CRISPR-Cas systems, Fanzor systems.

9 Aug 2024

New Findings Shed Light on ATM Activation in DNA Repair

New research from a team of genome scientists and DNA damage response experts breaks new ground in understanding the function of a protein currently limited in clinical trials for cancer treatments.

9 Aug 2024

Scientists Create Disease-Resistant Potatoes Using CRISPR

The global food system is under increasing pressure due to the compounding effects of climate change, which exacerbates the prevalence of pests and diseases in crops. Potatoes, being the third most important food crop worldwide, are particularly at risk. The quest for sustainable agricultural practices necessitates the development of crops that can withstand these adversities, prompting an urgent need for research into enhancing the inherent resilience of our staple foods.

9 Aug 2024

LINE-1 RNA from Ancient Viruses Promotes Bone Repair

Around half of the human genome is composed of DNA fragments originating from ancient viruses. These "transposable elements" (TEs) are now known to play various roles in modulating gene expression and disease development.

8 Aug 2024

Advancements in Grape Genomics Promise Enhanced Breeding Strategies

Grapes are economically and culturally significant worldwide, but climate change has posed substantial challenges to grape production in recent decades.

8 Aug 2024

Detailed Analysis of Cucumber Centromeres Uncovers Key DNA Sequences and Retrotransposons

Centromeres are crucial for chromosome segregation during cell division and consist of repetitive DNA sequences.

8 Aug 2024

Genetic Analysis of Potato and Phytophthora infestans During and After the Irish Potato Famine

In an examination of the genetic material found in historic potato leaves, North Carolina State University researchers reveal more about the tit-for-tat evolutionary changes occurring in both potato plants and the pathogen that caused the 1840s Irish potato famine.

6 Aug 2024