Heart Disease News and Research

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In vivo generation of engineered CAR T cells to treat heart injury

A novel immunotherapy strategy using in vivo generation of transient engineered chimeric antigen receptor (CAR) T cells, through the delivery of modified mRNA, can reduce fibrosis and restore cardiac function in a mouse model of heart failure, researchers report.

7 Jan 2022

300 million grant enables the establishment of new international stem cell research center

A grant from the Novo Nordisk Foundation of up to 300 million euro now enables the establishment of a major international research center focused on stem cell medicine.

20 Dec 2021

Study paves the way for more accurate prenatal genetic testing for congenital heart disease

One in every 100 babies is born with a congenital heart disease (CHD), and CHD is the major cause of death in newborns – however the genetic cause of these developmental disorders is not fully understood, hindering the development of accurate pre-natal genetic testing.

15 Dec 2021

Each person has their own unique “fingerprint” of protein activity, says study

A group of international scientists recently generated a new approach to identify the proteins in human cells that are crucial for increasing sugar absorption after exercise.

14 Dec 2021

Study of people from diverse ancestries provides a powerful tool for predicting heart disease risk

In a large-scale study of people from diverse ancestries, researchers narrowed down the number of genomic variants that are strongly associated with blood lipid levels and generated a polygenic risk score to predict elevated low-density lipoprotein cholesterol levels, a major risk factor for heart disease.

From National Human Genome Research Institute (NHGRI) 9 Dec 2021

Study shows why disruption of the body clock leads to inflammatory diseases

New research from RCSI has demonstrated the significant role that an irregular body clock plays in driving inflammation in the body's immune cells, with implications for the most serious and prevalent diseases in humans.

25 Nov 2021

Diet has a much stronger impact on the inner workings of cells than drugs

A study comparing the impact of diet versus drugs on the inner workings of our cells has found nutrition has a much stronger impact.

17 Nov 2021

Genetic testing underutilized in patients with cardiomyopathies and arrhythmias, study says

Heart failure and arrhythmia conditions are often considered as separate disorders, but genetic testing suggests there is much more overlap of these disorders than previously appreciated.

11 Nov 2021

Seasoning foods with herbs and spices may help improve heart health

Seasoning your food generously with herbs and spices isn't just a great way to make your meals tastier -; new research found it may have benefits for your heart's health, as well.

From Penn State University 11 Nov 2021

Study discusses outcomes of disclosing actionable genetic results to research participants

Over 120,000 patients have enrolled in the Mass General Brigham Biobank, offering access to crucial information related to their health history.

10 Nov 2021

Study finds several common genetic loci associated with dilated cardiomyopathy in U.S. veterans

A genome-wide association study has identified several common genetic loci (genetic locations) associated with dilated cardiomyopathy in U.S. veterans of European and African ancestry, according to preliminary research to be presented at the American Heart Association's Scientific Sessions 2021.

9 Nov 2021

Novel algorithm pinpoints genes associated with related genetic diseases

Scientists recently discovered almost two dozen genes that contribute to heart defects while analyzing genetic data from individuals.

8 Nov 2021

The 5:2 diet may provide a less overwhelming option for women with gestational diabetes

Weight loss after gestational diabetes can prevent the onset of type 2 diabetes. Yet finding the most effective way to lose weight and keep it off can be a challenge, especially for mothers with a new baby.

2 Nov 2021

Immune cell patterns can help predict kidney cancer patients' response to immunotherapy

Researchers at the Francis Crick Institute, The Royal Marsden NHS Foundation Trust and UCL have found immune cell patterns within tumors that can help predict if patients with kidney cancer will respond to immunotherapy.

29 Oct 2021

Diet-associated molecules in the gut are linked with aggressive prostate cancer

Cleveland Clinic researchers have shown for the first time that diet-associated molecules in the gut are associated with aggressive prostate cancer, suggesting dietary interventions may help reduce risk. Findings from the study were published in Cancer Epidemiology, Biomarkers & Prevention.

29 Oct 2021

Mice study shows how air pollution reduces sperm count by causing brain inflammation

Researchers have long known that air pollution can increase the risk of disorders such as obesity, diabetes, and fertility, but they did not know the exact mechanism for how it can lead to these health conditions.

26 Oct 2021

Stem cell therapy for heart disease enhanced with protein from fetal heart

The human heart, upon aging, slowly loses its capability to repair itself after injury. Damage caused by injuries like heart attack and cardiac ischemia—linked to decreased oxygen levels in the heart—can result in below normal capacity of heart functioning, making it tough for the patients to carry out daily activities.

25 Oct 2021