Inflammation News and Research

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Study Reveals STAP-1 Protein's Role in Immune Disorders

A new study highlights a potential therapeutic target for immune-related disorders, such as multiple sclerosis and asthma.

12 Mar 2024

Reducing Iron May Reverse Stem Cell Aging

It is fascinating to learn how researchers at the Albert Einstein College of Medicine and the National Cancer Institute-designated Montefiore Einstein Comprehensive Cancer Center (MECCC) have discovered a way to prevent or even reverse the function of hematopoietic (blood-forming) stem cells (HSCs) as they age.

11 Mar 2024

Astrocyte-Rich Brain Organoid Model Unveils Insights into Neuroinflammation

The brain is typically depicted as a complex web of neurons sending and receiving messages. But neurons only make up half of the human brain.

1 Mar 2024

Mutation in E. coli's Cellulose Machinery Unveiled as Cause of Severe Infections

Queensland researchers have discovered that a mutation allows some E. coli bacteria to cause severe disease in people while other bacteria are harmless, a finding that could help to combat antibiotic resistance.

22 Feb 2024

Study Reveals Gut Microbiome's Influence on Premature Aging in Chronic HIV Patients

The Wistar Institute's associate professor Mohamed Abdel-Mohsen, Ph.D., has demonstrated, with his lab and collaborators, a connection between viral damage to the gut and premature biological aging.

22 Feb 2024

Mayo Clinic Researchers Analyze Zombie Cells to Explain Aging

With age, cells can experience senescence, a state where they stop growing but continue releasing inflammatory and tissue-degrading molecules.

16 Feb 2024

Relation Between Faulty DNA Disposal System and Inflammation

The path from mitochondrial stress to leaking endosomes to immune system initiation in mouse cells is outlined by Salk scientists, providing new therapeutic targets to potentially reduce inflammation in aging and disease.

12 Feb 2024

Study Unveils Dual Role of 7-DHC in Ferroptosis and Cancer Cell Survival

Cell death is fundamental to life and, thus, healthy aging. In the realm of cellular biology, ferroptosis (a form of programmed cell death) has emerged not only as a focal point of research for its potential in eliminating cancer cells, but also its role in a plethora of other diseases, including neurodegenerative diseases such as Alzheimer's disease, eye diseases such as Retinitis pigmentosa and age-related macular degeneration, as well as ischemia, cardiovascular disease, liver disease, acute kidney injury and inflammation.

2 Feb 2024

New Research Finds Placenta Cells May Lower Blood Pressure

Scientists from La Trobe University and the Hudson Institute have demonstrated that cells from placentas could have therapeutic benefits for patients suffering from high blood pressure.

1 Feb 2024

RNAs on the Cell Surface Regulate Neutrophil Recruitment

In recent times, scientists have encountered RNAs venturing beyond their traditional cellular domains. A study conducted at Yale provides valuable insights into their activities in these unconventional locations.

23 Jan 2024

LJI Researchers Identify Late-Rising T Cells Crucial for CMV Control

Cytomegalovirus (CMV) is a pathogen that likes to lurk. Most adults already carry CMV, and they show no symptoms at all.

22 Jan 2024

Stem Cell-Derived Brain Organoids on Ax-3 Mission Seek to Improve Modeling for Neurodegenerative Diseases

More than 5 million people worldwide are living with neurodegenerative disorders like Parkinson’s disease and primary progressive multiple sclerosis (PPMS).

19 Jan 2024

Breakthrough 3D Vascular Sheet Mimics Atherosclerosis for High-Throughput Drug Screening

A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease, University of Alabama at Birmingham researchers report in the journal Biomaterials.

16 Jan 2024

Live-Cell Imaging Reveals How STING Activates Innate Immunity

When pathogens attack the body, the innate immune system goes to work protecting against the invading disease.

12 Jan 2024

Key Cytokine Pairs Driving Sepsis Damage Identified

One of the main causes of death in the ICU is sepsis, which is the result of an infection that causes the immune system to mistakenly target the body.

9 Jan 2024

Study Reveals Tissue-Specific Effects of JAK1 Signaling in Inflammation

Researchers at the Icahn School of Medicine at Mount Sinai have gained a deeper understanding of the nuanced roles of JAK inhibitors, or modulators, in inflammation across various cell types and tissues.

26 Dec 2023

Researchers Uncover Previously Unknown Inactive Form of p38a Protein

p38a protein, a key enzyme in the regulation of various cellular functions, plays a crucial role in some diseases, including cancer, chronic inflammation, and neurodegenerative conditions.

20 Dec 2023

Omicron's Cellular Senescence May Explain Cytokine Storms and Long-COVID

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 23, entitled, "Uncovering a unique pathogenic mechanism of SARS-CoV-2 omicron variant: selective induction of cellular senescence."

18 Dec 2023

Tailored Nanoparticles Deliver siRNA to Reduce Neuroinflammation in Alzheimer's Disease Models

Some Covid-19 vaccines safely and effectively used lipid nanoparticles (LNPs) to deliver messenger RNA to cells.

11 Dec 2023

Unveiling the Role of EVs in Bacterial Communication and Immune Surveillance

Messenger bubbles produced by human cells can pick up bacterial products and deliver them to other cells, University of Connecticut researchers report in the Nov. 16 issue of Nature Cell Biology.

28 Nov 2023