Metabolite News and Research

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Metabolites are the intermediates and products of metabolism. The term ''metabolite'' is usually restricted to small molecules.

New research reveals role of arginine metabolism in plant morphogenesis

Arginine metabolism boosts to make a plant body complex, according to new research by a collaborative team from Exploratory Research Center on Life and Living Systems (ExCELLS), National Institute for Basic Biology, RIKEN, Rikkyo University, Toyohashi University of Technology, Yamagata University, Chiba University, Hokkaido University, and University of Tokyo in Japan.

10 Sep 2020

Study elucidates the active role of glial cells in the nervous system

For the brain to work efficiently, it is important that a nerve impulse arrives at its destination as quickly and as precisely as possible. It has been long been known that the nerve fibres - also known as axons - pass on these impulses.

9 Sep 2020

Study: Bacterial cells from different species can combine into unique hybrid cells

Like humans, bacteria live together in communities, sometimes lending a hand -- or in the case of bacteria, a metabolite or two -- to help their neighbors thrive.

3 Sep 2020

Mice study shows naturally-occurring metabolite improves longevity

According to results from a study, middle-aged mice had a better “old age” when the naturally-occurring metabolite, called AKG, was added to their food.

2 Sep 2020

Flavonoids in sorghum roots may lead to development of frost-resistant crop

Flavonoid compounds -- produced by the roots of some sorghum plants -- positively affect soil microorganisms, according to Penn State researchers, who suggest the discovery is an early step in developing a frost-resistant line of the valuable crop for North American farmers.

14 Aug 2020

Study uncovers molecular mechanism of metabolite-mediated epigenome involved in organismal aging

Scientists have recently demonstrated that acetyl-CoA connects mitochondrial stress to the nuclear epigenome through the NuRD complex.

4 Aug 2020

Rare gene mutation eliminates immune cell population

A study has allowed researchers to identify a rare human gene mutation that removes a population of immune cells, called mucosal-associated invariant T cells.

27 Jul 2020

Study reveals the role of embryonic stem cells in cell repair

Chaperone-mediated autophagy (CMA) is a self-eating process that occurs in embryonic stem cells.

27 Jul 2020

Metabolomics can help understand the impact of calorie-restricted diets on aging

Changes in a few small molecules involved in a cell's metabolism seem to indicate whether a restricted "life extension" diet will actually extend, shorten, or have no effect on lifespan, a study of fruit flies has found.

10 Jul 2020

How upregulation of a single gene by SARs-CoV-2 can trigger cytokine storm

The SARS-CoV-19 virus initially has a limited capability to invade, attacking only one intracellular genetic target, the aryl hydrocarbon receptors (AhRs).

29 Jun 2020

Pseudotargeted metabolomics method can help analyze bile and amino acids

A team of researchers has come up with a procedure through which the pseudotargeted metabolomics technique can be systematically summarized and upgraded.

29 Jun 2020

Researchers discover unknown enzyme activity towards human endogenous substrates

Scientists have identified an enzymatic activity towards common drugs as well as significant human endogenous substrates, that was previously not known.

24 Jun 2020

Five-minute urine test measures quality of people's diets

Scientists have completed large-scale tests on a new type of five-minute urine test that measures the health of a person's diet, and produces an individual's unique urine 'fingerprint'.

23 Jun 2020

High sodium intake affects health of gut microbiome

Particularly in females with untreated hypertension, reducing salt intake to what's considered a healthier level appears to be good for both their gut microbiome and their blood pressure, scientists report.

10 Jun 2020

Environmental Contaminants Alter Gut Microbiome

The microbes that inhabit our bodies are influenced by what we eat, drink, and breathe and most of us are exposed to environmental contaminants.

22 May 2020

Researchers use CRISPR technology to control many genes simultaneously

Researchers from UMD are using CRISPR technology in an effort to develop first-of-their-kind microelectronic devices that link with biological systems.

21 May 2020

Brainhealth Research Advances Understanding Of Differences In Effects Of Cannabis Use

Researchers at the Center for BrainHealth® recently published findings underscoring differences between men and women's craving or desire to consume cannabis.

19 May 2020

Engineers Develop Precision Injection System For Plants

While the human world is reeling from one pandemic, there are several ongoing epidemics that affect crops and put global food production at risk.

28 Apr 2020

Study Reveals Bile Metabolite Of Gut Microbes Boosts Immune Cells

A study has discovered a novel means by which bacterial colonies in the small intestine support the generation of regulatory T cells.

20 Apr 2020