Surgery News and Research

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Oral difelikefalin could reduce the intensity of itch in patients with notalgia paresthetica

Notalgia paresthetica-;a nerve disorder characterized by a persistent itch in the upper back-;is a common and underdiagnosed condition worldwide.

9 Feb 2023

Antibody that blocks VEGF-B could be a potential therapeutic option for fatty liver disease

There is currently no drug for treating non-alcoholic fatty liver disease, which affects many people with type 2 diabetes and which can result in other serious liver diseases.

6 Feb 2023

Losartan prevents immunotherapy-related edema, improves survival in glioblastoma mouse models

Patients with glioblastoma-;the deadliest type of primary brain tumor-;may potentially benefit from immunotherapy medications called immune checkpoint inhibitors that stimulate an immune response against cancer cells.

3 Feb 2023

Newly discovered genetic mutation may be a root cause of severe cases of childhood glaucoma

An international team of scientists led by Mass Eye and Ear, a member of Mass General Brigham, and Boston Children's Hospital, has discovered a new genetic mutation that may be a root cause of severe cases of childhood glaucoma, a devastating condition that runs in families and can rob children of their vision by 3 years of age.

30 Jan 2023

Analysis of pancreatic cancer's microenvironment reveals cause of tumor cell resistance to immunotherapy

A new study that analyzed the tumor microenvironment of pancreatic cancer revealed the cause of tumor cell resistance to immunotherapy and resulted in new treatment strategies.

27 Jan 2023

Predictive classifier identifies patients who can skip radiation therapy

According to the findings of a meta-analysis proposed at the San Antonio Breast Cancer Symposium held on December 6–10th, 2022, patients with invasive breast cancer who had low scores on an investigational gene molecular signature seemed to have similar rates of local recurrence regardless of whether they received adjuvant radiation therapy after breast-conserving surgery.

12 Dec 2022

NIH funds research on mRNA vaccines to stop cancer development

The National Cancer Institute at the National Institutes of Health has awarded a multidisciplinary team of Weill Cornell Medicine researchers a five-year $5.7 million grant to support a center dedicated to creating messenger RNA (mRNA) vaccines to prevent the development of cancer in at-risk groups.

15 Nov 2022

Enhancing outcomes after surgery of breast cancer patients with miR-145

According to research results published online ahead of print in the Journal of the American College of Surgeons (JACS), microRNA (miRNA) can be used as a biomarker to identify which individuals are most likely to experience breast cancer recurrence and mortality.

8 Nov 2022

New bioprinting platform to replicate tumors in 3D spheroids

Bowel cancer patients could in future benefit from a new 3D bioprinting technology which would use their own cells to replicate the complex cellular environment of solid tumors in 3D models.

3 Nov 2022

Molecular responses of Pseudomonas aeruginosa to hydroquinine

Researchers investigating the effects of an organic compound on drug-resistant bacteria found how it can impede and destroy a germ that causes significant illness or even death in some situations.

1 Nov 2022

Combined spacing and retrieval practice helps to better remember information

Whether you're trying to ace a test or pick up a new hobby, Iowa State Psychology Professor Shana Carpenter says combining two strategies – spacing and retrieval practice – is key to success.

21 Oct 2022

New gene linked to the growth of colon cancer discovered

Researchers at Mount Sinai’s Tisch Cancer Institute have discovered a new gene that is crucial to the development of colon cancer and established that inflammation in the region surrounding the tumor can contribute to the development of tumor cells.

20 Oct 2022

New approach to identify cancerous tissue for surgical removal

It is crucial to distinguish between tumors and healthy tissues during cancer surgery. Fluorescent markers can assist in this process by improving tumor contrast during surgery.

13 Oct 2022

Adults with congenital blindness experience striking recoveries of night vision after gene therapy

Adults with a genetic form of childhood-onset blindness experienced striking recoveries of night vision within days of receiving an experimental gene therapy, according to researchers at the Scheie Eye Institute in the Perelman School of Medicine at the University of Pennsylvania.

11 Oct 2022

The strategy used by metastatic cancer cells to invade the liver identified

The alternative pathway for liver metastasis has been revealed by a team of researchers.

5 Oct 2022

Common genetic variants associated with beat synchronization identified

The first large-scale genomic study of musicality revealed 69 genetic variations linked with beat synchronization, which denotes the ability to move in time with the beat of the music.

From Vanderbilt University 20 Sep 2022

A new holographic microscope developed to observe neural networks in brain

Scientists headed by Associate Director Wonshik Choi of the Center for Molecular Spectroscopy and Dynamics in the Institute for Basic Science, Professor Kim Moonseok of The Catholic University of Korea, and Professor Myunghwan Choi of Seoul National University designed a new kind of holographic microscope.

19 Sep 2022

Using human saliva to treat infections that are resistant to antibiotics

Tens of millions of individuals throughout the world suffer from antibiotic resistance every year. The CDC reports that more than 35,000 people die each year as a result of more than 2.8 million antibiotic-resistant infections that take place there each year.

2 Sep 2022

Diseased connective tissue cells alter the physical structure of their genomes

Researchers at Penn Medicine have found that when cells are impacted by the disease, the physical structure of their genome changes.

25 Aug 2022

Mount Sinai and Regeneron Genetics Center launch a large-scale genome sequencing project

Mount Sinai Health System and the Icahn School of Medicine at Mount Sinai have launched a new human genome sequencing research project called the Mount Sinai Million Health Discoveries Program with the Regeneron Genetics Center (RGC), part of the industry-leading, New York-based biotechnology company Regeneron.

12 Aug 2022