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Preclinical study describes a promising approach to regenerate damaged cartilage

Osteoarthritis – a painful condition that results from the deterioration of the cartilage in our joints – affects millions of people worldwide.

6 Jun 2022

Researchers developed a weapon to combat drug-resistant malaria

As the efficiency of conventional antimalarial medications deteriorates, a novel approach to combating malaria that sees the disease turn against itself could provide a viable treatment for the hundreds of millions of people affected globally every year.

6 Jun 2022

Research findings provide clues on the properties that might have made A. baumannii a successful pathogen

Over 670,000 people in Europe become ill each year as a result of pathogenic bacteria that are resistant to antibiotics, and 33,000 people die as a result of the diseases they cause. Pathogens that are resistant to multiple antibiotics at the same time are particularly dangerous.

6 Jun 2022

Study discovers new antibiotics effective against drug-resistant tuberculosis

Every year, 1.5 million people die from infections caused by Mycobacterium tuberculosis. Antibiotics are available to treat tuberculosis, but the bacteria has evolved multi-drug resistant (MDR), extensively drug-resistant (XDR), and fully drug-resistant (TDR) strains in recent years.

1 Jun 2022

Damaged liver treated in perfusion machine for three days and then implanted into a cancer patient

The multidisciplinary Zurich research team Liver4Life has succeeded in doing something during a treatment attempt that had never been achieved in the history of medicine until now: it treated an originally damaged human liver in a machine for three days outside a body and then implanted the recovered organ into a cancer patient.

1 Jun 2022

Endogenous retroviruses in the human genome are likely to pose a risk in regenerative medicine

Scientists from Kumamoto University used next-generation sequencing to analyze human endogenous retrovirus (HERV) integration sites and found that these primitive retroviruses can retrotranspose (DNA sequence insertion with RNA mediation) into iPS cells.

31 May 2022

Fast-breeding sea urchin species may be a game changer in genetic research

Many people may not realize that the humble sea urchin is a titan when it comes to the study of biology. Now, researchers from Japan have discovered that sea urchins could help biological studies go further than ever before.

30 May 2022

Extinction risk of reptiles is widely underestimated in the IUCN Red List

The iconic Red List of Threatened Species, published by the International Union for Conservation of Nature (IUCN), identifies species at risk of extinction.

30 May 2022

Scientists develop powerful tools using CRISPR-Cas9 to repair genetic diseases

CRISPR has marked the beginning of a new era in genomic medicine. The popular CRISPR-Cas9 has generated plenty of potent methods for curing genetic diseases.

30 May 2022

Drugs used for myelodysplastic syndrome could potentially activate a sleeping oncogene

Hypomethylating agents (HMA) are currently used as a first-line treatment for patients with myelodysplastic syndrome (MDS) - a group of disorders where there is insufficient production of healthy mature blood cells in the bone marrow - and increasingly in other diseases, but their mechanism of action remains unclear.

From National University of Singapore (NUS) 27 May 2022

Genetic testing advances help to uncover primary immune deficiency diseases

Infections caused by primary immunodeficiency diseases (PID) can be persistent and life-threatening. More than 450 PIDs have been identified, yet diagnosing them quickly and accurately remains a difficulty.

27 May 2022

A novel mechanism shared by mutations in varied genes could help treat neurological diseases

Researchers at Tel Aviv University, led by Prof. Illana Gozes from the Department of Human Molecular Genetics and Biochemistry at the Sackler Faculty of Medicine and the Sagol School of Neuroscience, have unraveled a mechanism shared by mutations in the genes ADNP and SHANK3, which cause autism, schizophrenia, and other conditions.

25 May 2022

Study shows polymersome can effectively deliver PARP1 siRNA to treat breast cancer

Small interfering RNAs, or siRNAs, have the potential to cure tumors by targeting knocking down oncogenes that drive tumor development while avoiding the damage associated with chemotherapy.

25 May 2022

Easy-to-find soft corals make the elusive "anti-cancer" compound, scientists report

The bottom of the ocean is full of mysteries but scientists have recently uncovered one of its best-kept secrets. For 25 years, drug hunters have been searching for the source of a natural chemical that had shown promise in initial studies for treating cancer.

From The University of Utah 24 May 2022

Research may lead to new therapies for metabolic disorders and other diseases

Researchers at UT Southwestern have uncovered a molecular path that allows cells to detect when their lipid supplies are running low, triggering a flurry of activity that avoids starvation.

23 May 2022

Type I interferon may activate a potent immune response against harmful viruses

Researchers at McMaster University have discovered not only how specific viral infections potentially cause tissue damage, but also how to prevent it.

23 May 2022

Researchers create open-access atlases of human immune cells in adults

Previously unknown immune cell types throughout development and adulthood have been identified, providing new insights into how the human immune system functions.

18 May 2022

Researchers identify gene mutation to have the potential to induce higher intelligence in humans

When genes mutate, serious diseases of the human nervous system can result. Scientists from Leipzig University and the University of Würzburg have now used fruit flies to show how, in addition to the negative impact, mutation of a neuronal gene can have a beneficial impact—higher IQ in humans.

12 May 2022

Scientist reveals the impact of mitochondria in metastatic prostate cancer

Prostate cancer that has spread to other regions of the body is commonly treated with hormone treatment, but many individuals develop resistance to it, making their disease more aggressive and potentially fatal.

12 May 2022

Scientists detect rare genetic signs of drug-resistant tuberculosis with the aim to stop disease progression

Many people believe tuberculosis (TB) is a disease of the past. Nonetheless, it claims over a million lives each year. Furthermore, the problem is escalating as Mycobacterium tuberculosis—the pathogen that causes tuberculosis develops resistance to the antibiotics used to treat the disease.

12 May 2022

Medicine News and Research

Preclinical study describes a promising approach to regenerate damaged cartilage

Researchers developed a weapon to combat drug-resistant malaria

Research findings provide clues on the properties that might have made A. baumannii a successful pathogen

Study discovers new antibiotics effective against drug-resistant tuberculosis

Damaged liver treated in perfusion machine for three days and then implanted into a cancer patient

Endogenous retroviruses in the human genome are likely to pose a risk in regenerative medicine

Fast-breeding sea urchin species may be a game changer in genetic research

Extinction risk of reptiles is widely underestimated in the IUCN Red List

Scientists develop powerful tools using CRISPR-Cas9 to repair genetic diseases

Drugs used for myelodysplastic syndrome could potentially activate a sleeping oncogene

Genetic testing advances help to uncover primary immune deficiency diseases

A novel mechanism shared by mutations in varied genes could help treat neurological diseases

Study shows polymersome can effectively deliver PARP1 siRNA to treat breast cancer

Easy-to-find soft corals make the elusive "anti-cancer" compound, scientists report

Research may lead to new therapies for metabolic disorders and other diseases

Type I interferon may activate a potent immune response against harmful viruses

Researchers create open-access atlases of human immune cells in adults

Researchers identify gene mutation to have the potential to induce higher intelligence in humans

Scientist reveals the impact of mitochondria in metastatic prostate cancer

Scientists detect rare genetic signs of drug-resistant tuberculosis with the aim to stop disease progression

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