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New class of protein materials can influence cell signaling

A new study has revealed that a novel class of protein material that communicates with living cells without being absorbed by them can affect cell signaling. The protein material does this by attaching and sequestering cell surface receptors.

7 Jan 2021

Study may lead to new treatments for autoimmune diseases

According to a research team, headed by Decio L. Eizirik, MD, PhD, a Scientific Director from the Indiana Biosciences Research Institute Diabetes Center, new treatments for autoimmune disorders can be identified by studying both target tissues and the immune system together.

7 Jan 2021

Researchers create molecular ON-OFF switches to regulate CAR T cell activity

CAR T cells are a breakthrough class of effective but often toxic cancer therapies. To prevent overactivation, switchable CAR T cells were engineered that can be turned on and off with an approved, widely used cancer drug.

7 Jan 2021

Scientists resolve long-standing debate over key mechanism involved in gene silencing

Scientists from Massachusetts General Hospital (MGH) have resolved a long-standing debate over how crucial gene-silencing protein detects its targets.

5 Jan 2021

Scientists modify toxic pesticide to treat antibiotic-resistant bacteria

A significant class of heterocyclic compounds, called N-Aryl-C-nitroazoles, is used as fungicides and pesticides. But these substances could be harmful to human beings and cause mutations.

4 Jan 2021

Study identifies the effects of nutritional deficiency on patient survival after cardiac surgery

Nutrients are the structural components of food that the body needs to function properly. They are divided into macronutrients (proteins, fats, carbohydrates) and micronutrients (vitamins, provitamins, various minerals, and so on). Their shortage is called nutritional deficiency.

4 Jan 2021

Twist‐and‐squeeze mechanism of transporter protein confers cancer drug resistance

In 1986, cellular biochemist Kazumitsu Ueda, currently at Kyoto University's Institute for Integrated Cell-Material Sciences, discovered that a protein called ABCB1 could transport multiple chemotherapeutics out of some cancer cells, making them resistant to treatment. How it did this has remained a mystery for the past 35 years.

29 Dec 2020

Chromosomal instability is associated with cancer's aggressiveness

Cancer cells are known for spreading genetic chaos. As cancer cells divide, DNA segments and even whole chromosomes can be duplicated, mutated, or lost altogether.

29 Dec 2020

HKU researchers develop new drug discovery strategy targeting membrane proteins on live cells

A research team led by Dr Xiaoyu LI from the Research Division for Chemistry, Faculty of Science, in collaboration with Professor Yizhou LI from School of Pharmaceutical Sciences, Chongqing University and Professor Yan CAO from School of Pharmacy, Second Military Medical University in Shanghai has developed a new drug discovery method targeting membrane proteins on live cells.

29 Dec 2020

New knowledge on cancer's own intelligence

Dr. J. James Frost and The International Journal of Unconventional Computing will soon be publishing "Cancer's Intelligence" which reports that Cancer can be analyzed as an intelligent system of collaborating and computing cells.

28 Dec 2020

Kobe University and Sysmex conduct joint research on new blood test for identifying COVID-19

Kobe University and Sysmex Corporation have been engaged in joint research on the ELISPOT method, a new blood test for identifying the novel coronavirus disease (COVID-19).

28 Dec 2020

Scientists discover new class of compounds for combating antimicrobial resistance

Wistar Institute scientists have discovered a new class of compounds that uniquely combine direct antibiotic killing of pan drug-resistant bacterial pathogens with a simultaneous rapid immune response for combatting antimicrobial resistance (AMR). These finding were published today in Nature.

24 Dec 2020

Triple drug combination keeps people with metastatic colon cancer disease free for longer time

Researchers from SWOG Cancer Research Network, a cancer clinical trials group funded by the National Cancer Institute (NCI), part of the National Institutes of Health, have shown that a triple drug combination - of irinotecan, cetuximab, and vemurafenib - is a more powerful tumor fighter and keeps people with metastatic colon cancer disease free for a significantly longer period of time compared with patients treated with irinotecan and cetuximab.

24 Dec 2020

Scientists identify new weapon to fight against antibiotic-resistant bacteria

As scientists around the globe wage war against a novel, deadly virus, one University of Colorado Boulder lab is working on new weapons to battle a different microbial threat: a rising tide of antibiotic-resistant bacteria which, if left unchecked, could kill an estimated 10 million people annually by 2050.

24 Dec 2020

Drugs News and Research

New class of protein materials can influence cell signaling

Study may lead to new treatments for autoimmune diseases

Researchers create molecular ON-OFF switches to regulate CAR T cell activity

Scientists resolve long-standing debate over key mechanism involved in gene silencing

Scientists modify toxic pesticide to treat antibiotic-resistant bacteria

Study identifies the effects of nutritional deficiency on patient survival after cardiac surgery

Twist‐and‐squeeze mechanism of transporter protein confers cancer drug resistance

Chromosomal instability is associated with cancer's aggressiveness

HKU researchers develop new drug discovery strategy targeting membrane proteins on live cells

New knowledge on cancer's own intelligence

Kobe University and Sysmex conduct joint research on new blood test for identifying COVID-19

Scientists discover new class of compounds for combating antimicrobial resistance

Triple drug combination keeps people with metastatic colon cancer disease free for longer time

Scientists identify new weapon to fight against antibiotic-resistant bacteria

Study uncovers how shattered chromosomes make cancer cells more aggressive

Researchers report a potential cancer drug that targets mitochondrial function

Researchers demonstrate potential preventive treatment for Crohn's disease

Anti-hypertension drug prolongs lifespan in C. elegans, research shows

Scientists observe detailed images of spike proteins in coronavirus

Novel compounds may lead to potential treatment for rare terminal childhood illness

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