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New analysis technique could pave way for major breakthroughs in immunotherapy

In a new study, researchers at Uppsala University have been able to show differences in how Rituximab, a monoclonal antibody drug, interacts with the blood of healthy individuals compared to patients with chronic lymphatic leukaemia.

14 Dec 2020

Study elucidates genes responsible for Glioblastoma invasiveness

One of the hallmarks of Glioblastoma (GBM), the most aggressive type of brain cancer, is its high invasive capacity, which leads to its expansion into the normal brain tissue.

14 Dec 2020

Olefins formed by light-driven catalyst can help produce drugs, agrochemicals

Taking a cue from light-sensing bacteria that live close to hot oceanic vents, synthetic chemists from Rice University have identified a mild process to produce useful hydrocarbons, called alkenes, or olefins.

11 Dec 2020

New antibiotic can help treat drug-resistant pathogens

Researchers from Johns Hopkins University and Medicine have designed a potential new antibiotic for a pathogen that is highly resistant to drugs and is often lethal to individuals suffering from lung diseases, including cystic fibrosis.

11 Dec 2020

Revolutionary CRISPR-based genome editing system treatment destroys cancer cells

Researchers at Tel Aviv University have demonstrated that the CRISPR/Cas9 system is very effective in treating metastatic cancers.

11 Dec 2020

Scientists aim to treat and prevent disease by understanding exercise benefits

A top exercise researcher and colleagues at the University of Virginia School of Medicine have launched an ambitious effort to understand the whole-body benefits of exercise so that doctors can use that information to prevent and treat disease.

11 Dec 2020

A genetic shortcut to help visualize proteins at work

A group at Gladstone Institutes and UC San Francisco (UCSF) has demonstrated that a large-scale and systematic genetic approach can indeed yield reliable and detailed information on the structure of protein complexes.

11 Dec 2020

Research shows how microbubbles can be used to administer potent cancer drugs

New research has shown how microbubbles carrying powerful cancer drugs can be guided to the site of a tumour using antibodies.

11 Dec 2020

Novel amplification-free rapid SARS-CoV-2 nucleic acid detection platform based on HC-FIA

The COVID-19 pandemic has highlighted the need for rapid and accurate nucleic acid detection at the point of care.

11 Dec 2020

Study shed light on how genes affect the risk for coronary artery disease

Researchers at the University of Virginia have shed light on how our genes affect our risk for coronary artery disease, the most common form of heart disease.

11 Dec 2020

Scientists use honey bee peptide to design RBC carriers that deliver therapeutic proteins

Most often, protein therapies are more selective and potent toward their biochemical targets when compared to other types of medicines, specifically small molecules.

10 Dec 2020

Genetically modified tomato can provide a new source of Parkinson’s disease drug

L-DOPA is a drug used for treating Parkinson’s disease, and now researchers have created a tomato that is enriched with this drug. This innovation could lead to a new, inexpensive source of one of the most essential medicines in the world.

10 Dec 2020

Appendiceal cancer among young patients harbors a distinct biology, shows study

The first study to compare molecular landscapes of early-onset and late-onset appendiceal cancer has revealed distinct non-silent mutations in the tumors of younger patients, setting the stage for the development of potential therapeutic advances for this rare disease.

From Vanderbilt University 10 Dec 2020

New microrobots show promise for future medical applications

Cancer drugs have side effects, so for many years, scientists have been exploring ways to transport the active substances to a tumour in the body as precisely as possible. That is the only place that drugs should take effect.

9 Dec 2020

Researchers identify key molecular processes used by coronaviruses to survive

When a coronavirus--including SARS-CoV-2, which causes COVID-19--infects someone, it hijacks the person's cells, co-opting their molecular machinery for its own survival and spread.

9 Dec 2020

Gene therapy and medication can provide certain beneficial effects of physical exercise

Jose Bianco Moreira from NTNU is now convinced that gene therapy can be used to achieve the positive health benefits of physical exercise.

7 Dec 2020

CAR T-cell therapy reduced cancer cells in patients with advanced non-Hodgkin lymphoma

A CAR T-cell therapy known as axicabtagene ciloleucel (axi-cel) drove cancer cells to undetectable levels in nearly 80% of patients with advanced non-Hodgkin lymphoma (NHL) in a phase 2 clinical trial, Dana-Farber Cancer Institute investigators report at the virtual 62nd American Society of Hematology (ASH) Annual Meeting.

7 Dec 2020

Subcutaneous injection of teclistamab drug shows promise in treating aggressive multiple myeloma

A subcutaneous injection of the immune-boosting drug teclistamab was found to be safe and elicit responses in a majority of patients with relapsed or refractory multiple myeloma, according to findings from a multi-institutional phase I study being presented by Alfred L. Garfall, MD, an assistant professor of Medicine in the division of Hematology-Oncology in the Perelman School of Medicine at the University of Pennsylvania, at the annual American Society of Hematology & Exposition Meeting on Dec. 5 (abstract #180).

7 Dec 2020

Researchers determine 3D structures of RNA hybridization with artificial nucleic acids

As medical research progresses, traditional treatment protocols are being rapidly exhausted. New approaches to treat diseases that do not respond to conventional drugs are the need of the hour.

4 Dec 2020

Drug meant for bacterial infections can combat weight gain

A drug originally developed to treat bacterial infections has proved capable of boosting the metabolism and attenuating the weight gain induced by a fatty diet in tests with mice. The study was conducted at the University of Campinas (UNICAMP) with FAPESP's support, and the findings have just been published in the journal Science Advances.

3 Dec 2020

Drugs News and Research

New analysis technique could pave way for major breakthroughs in immunotherapy

Study elucidates genes responsible for Glioblastoma invasiveness

Olefins formed by light-driven catalyst can help produce drugs, agrochemicals

New antibiotic can help treat drug-resistant pathogens

Revolutionary CRISPR-based genome editing system treatment destroys cancer cells

Scientists aim to treat and prevent disease by understanding exercise benefits

A genetic shortcut to help visualize proteins at work

Research shows how microbubbles can be used to administer potent cancer drugs

Novel amplification-free rapid SARS-CoV-2 nucleic acid detection platform based on HC-FIA

Study shed light on how genes affect the risk for coronary artery disease

Scientists use honey bee peptide to design RBC carriers that deliver therapeutic proteins

Genetically modified tomato can provide a new source of Parkinson’s disease drug

Appendiceal cancer among young patients harbors a distinct biology, shows study

New microrobots show promise for future medical applications

Researchers identify key molecular processes used by coronaviruses to survive

Gene therapy and medication can provide certain beneficial effects of physical exercise

CAR T-cell therapy reduced cancer cells in patients with advanced non-Hodgkin lymphoma

Subcutaneous injection of teclistamab drug shows promise in treating aggressive multiple myeloma

Researchers determine 3D structures of RNA hybridization with artificial nucleic acids

Drug meant for bacterial infections can combat weight gain

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