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80-year-old antibiotic redesigned for new medical uses

Physicians and scientists have long searched the natural world for chemicals that can improve human health.

5 Oct 2020

Millimetre-Precision Drug Delivery To The Brain

Researchers have developed a method for concentrating and releasing drugs in the brain with pinpoint accuracy.

5 Oct 2020

Study shows patients can benefit from personalized cancer therapy

Scientists have shown that patients, who are receiving care for cancer, have a greater chance of surviving if they received personalized cancer treatment.

From UC San Diego 5 Oct 2020

Study offers explanation to why people respond differently to the same drug

Scientists at Scripps Research have comprehensively mapped how a key class of proteins within cells regulates signals coming in from cell surface receptors.

5 Oct 2020

Study unravels how immunotherapy is 'uniquely suppressed' by liver cancers

Though cancer immunotherapy has become a promising standard-of-care treatment--and in some cases, perhaps a cure--for a wide variety of different cancers, it doesn't work for everyone, and researchers have increasingly turned their attention to understanding why.

5 Oct 2020

Researchers gain insight into potentiating effect of selective drugs

Some highly selective drugs cause unexpected effects in nerve cells: they not only reduce the activation of certain receptors, but also their inactivation.

5 Oct 2020

Gut bacteria may play a role in the treatment of prostate cancer

New research shows how the gut microbiome communicates with an oral drug in prostate cancer patients.

30 Sep 2020

New platform can enhance the efficiency of cancer immunotherapy

Antibody-based immunotherapy is one of treatment options for cancer immunotherapy by modulating our immune system with therapeutic antibodies.

30 Sep 2020

Epigenetic alterations drive late-onset Alzheimer's disease

New findings suggest that late-onset Alzheimer's Disease is driven by epigenetic changes -- how and when certain genes are turned on and off -- in the brain. Results were published today in Nature Genetics.

29 Sep 2020

New precision drug targeting cancer's ability to repair DNA shows promise

A new precision drug which stops cancer from repairing its DNA has shown promise in an early-stage clinical trial - highlighting the potential of a new class of drugs known as ATR inhibitors.

29 Sep 2020

Cocaine addiction: Impact of genetic mutations elucidated

Cocaine addiction is a chronic disorder with a high rate of relapse for which no effective treatment is currently available.

28 Sep 2020

Stem cells can repair parkinson's-damaged circuits in mouse brains

The mature brain is infamously bad at repairing itself following damage like that caused by trauma or strokes, or from degenerative diseases like Parkinson's.

28 Sep 2020

Computational model effectively identifies genetic mutations in breast tumors

Researchers at Lund University in Sweden have developed a computational model which is effective in detecting and identifying genetic mutations in breast tumors. The study, the largest of its kind in the world, includes results from over 3 200 patients with breast cancer.

25 Sep 2020

New antibodies could form the basis of a broad-spectrum flu drug

Researchers have identified two antibodies that protect mice against lethal infections of influenza B virus, report scientists at Washington University School of Medicine in St. Louis and Icahn School of Medicine at Mount Sinai.

25 Sep 2020

Researchers identify a driver of drug resistance in some cancers

Patients with BRCA1/2 mutations are at higher risk for breast, ovarian and prostate cancers that can be aggressive when they develop - and, in many cases, resistant to lifesaving drugs.

24 Sep 2020

Druggable pocket in SARS-CoV-2 Spike protein can help eliminate COVID-19

Researchers have identified a druggable pocket in the SARS-CoV-2 Spike protein that could be utilized to prevent the virus from infecting human cells.

24 Sep 2020

Nanoparticle SARS-CoV-2 tool could accelerate the search for drugs

A team of scientists from the National Center for Advancing Translational Sciences and Naval Research Laboratory in Washington, D.C., has developed a new tool that mimics how SARS-CoV-2 -- the virus that causes COVID-19 -- infects a cell, information that could potentially speed the search for treatments against the disease.

22 Sep 2020