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Defined regulatory framework needed for developing live biotherapeutic products

The Pharmabiotic Research Institute (PRI), Europe's only regulatory expertise centre for the development of microbiome-based drug products, has announced the publication of a review titled "Live biotherapeutic products: the importance of a defined regulatory framework".

18 Sep 2020

Mathematical model can determine the impact of immune system on tumor evolution

Researchers at Queen Mary University of London, The Institute of Cancer Research, London, and the Moffitt Cancer Centre have created a mathematical model that can determine the impact of the immune system on tumor evolution.

17 Sep 2020

Study pinpoints specific genes that cause ovarian cancer

High-grade serious ovarian carcinoma is the fifth major cause of cancer-associated deaths in women in the United States.

14 Sep 2020

Researchers identify the cause for Parkinson's disease and potential treatments

In a seven-year research effort, an international team of scientists has clarified the cause for certain genetic forms of Parkinson's disease, and has identified potential pharmacological treatments.

14 Sep 2020

New study can help develop effective COVID-19 vaccine

According to a new study, a detailed analysis of antibody responses in patients affected by COVID-19 could help develop an effective vaccine.

14 Sep 2020

Study sheds new light on the structure and function of ‘immortality protein’

The nuclear magnetic resonance spectrometer of Kazan Federal University played a crucial role in analyzing the telomerase of Hansenula polymorpha.

14 Sep 2020

Developing a Trace Vapor Generator for Explosives and Narcotics

In this interview, Dr Braden Giordano speaks to AZoLifeSciences about their new trace vapor generator that detects narcotics and explosives.

From United States Naval Research Laboratory 11 Sep 2020

New study unravels genetic vulnerability in breast cancer tumors

A new study has unraveled a genetic vulnerability that exists in almost 10% of all breast cancer tumors.

11 Sep 2020

Protein aggregation reduces elasticity of blood vessels during aging

Deposits of a protein called "Medin", which manifest in virtually all older adults, reduce the elasticity of blood vessels during aging and hence may be a risk factor for vascular dementia.

10 Sep 2020

Researchers review the role of macrophage activation syndrome in COVID-19

A major percentage of COVID-19 cases have become so severe that hospital admissions have become mandatory for both monitoring and treatment.

10 Sep 2020

Novel method produces anti-inflammatory substances with controlled quality

Anti-inflammatory substances based on components of human cells could one day improve treatment in patients. Researchers at the Institute of Pharmacy at Martin Luther University Halle-Wittenberg (MLU) have developed a method for producing those substances with controlled quality.

10 Sep 2020

Computer-designed proteins protect lab-grown human cells from SARS-CoV-2

Computer-designed small proteins have now been shown to protect lab-grown human cells from SARS-CoV-2, the coronavirus that causes COVID-19.

10 Sep 2020

Human evolution shaped by pathogens and cell-autonomous immunity

Every human cell harbors its own defenses against microbial invaders, relying on strategies that date back to some of the earliest events in the history of life, researchers report.

10 Sep 2020

In-depth study of kidney tumors reveals novel markers of response to immunotherapy

Treatments for kidney cancer have improved considerably over the past few decades. In 1988, when Memorial Sloan Kettering oncologist Robert Motzer started researching the disease, the average survival was less than one year.

9 Sep 2020

Researchers explore link between uncontrolled inflammation and brain's immune cells

Inspired by the need for new and better therapies for neurodegenerative diseases, such as Parkinson's disease and Alzheimer's disease, Rutgers University researchers are exploring the link between uncontrolled inflammation within the brain and the brain's immune cells, known as microglia.

9 Sep 2020

New study can help reduce the failure rate of drug development for various diseases

A novel genetic analysis of blood protein concentrations has shown how genetic information can be applied to support the prioritization of drug targets.

9 Sep 2020

New gene test predicts risk of drug-induced liver injury

Researchers who were exploring ways to establish the feasibility of batches of small liver organoids have now identified a new testing approach.

9 Sep 2020

Researchers develop cellular roadmaps to predict the body’s susceptibility to coronavirus

A new study has created promising roadmaps to predict how the novel coronavirus infects organs and detects the factors that could limit the infection.

7 Sep 2020

New technology reveals experimental drugs that help suppress the growth and spread of tumor

A new technology that allows researchers to peer inside malignant tumors shows that two experimental drugs can normalize aberrant blood vessels, oxygenation, and other aspects of the tumor microenvironment in non-small cell lung cancer (NSCLC), helping to suppress the tumor's growth and spread, UT Southwestern researchers report.

4 Sep 2020

Study highlights the effects of antibiotics on breast milk microbiota milk

A team led by researchers at the University of Toronto and The Hospital for Sick Children has found that mothers of preterm babies have highly individual breast milk microbiomes, and that even short courses of antibiotics have prolonged effects on the diversity and abundance of microbes in their milk

From University of Toronto 4 Sep 2020